Maria A Troyanova-Wood,Vladislav V Yakovlev
Maria A Troyanova-Wood
We propose and demonstrate, first on simulated spectra and then experimentally, a novel approach to correct the undesired background distortions in the Brillouin spectra caused by molecular filter's absorption, fluorescent emission, ambient...
Ren A Odion,Yang Liu,Tuan Vo-Dinh
Ren A Odion
Cancer is among the leading cause of death around the world, causing close to 10 million deaths each year. Significant efforts have been devoted to developing novel technologies that can detect and treat cancer early and effectively to redu...
Greatly Enhanced Single Particle Fluorescence Detection Using High Refractive Index Liquid-Core Waveguides [0.03%]
利用高折射率液体芯波导增强单粒子荧光检测技术
Gopikrishnan Gopalakrishnan Meena,Joel G Wright Jr,Aaron R Hawkins et al.
Gopikrishnan Gopalakrishnan Meena et al.
High sensitivity and easy integration with microfabrication techniques has made silicon photonics one of the leading technologies used to build biosensors for diagnostic applications. Here we introduce a new silicon dioxide based optofluidi...
Micro Air-Pulse Spatial Deformation Spreading Characterizes Degree of Anisotropy in Tissues [0.03%]
微空气脉冲空间变形传播表征组织各向异性程度
Fernando Zvietcovich,Manmohan Singh,Yogeshwari S Ambekar et al.
Fernando Zvietcovich et al.
In optical coherence elastography (OCE), air-pulse stimulation has been widely used to produce propagation of mechanical waves for elastic characterization of tissues. In this paper, we propose the use of spatial deformation spreading (SDS)...
In Vivo Detection of Gold Nanoshells in Tumors Using Diffuse Optical Spectroscopy [0.03%]
利用扩散光学光谱法检测肿瘤中的金纳米壳
Raiyan T Zaman,Parmeswaran Diagaradjane,James C Wang et al.
Raiyan T Zaman et al.
This study demonstrates the use of diffuse optical spectroscopy (DOS) for the noninvasive measurement of gold nanoshell concentrations in tumors of live mice. We measured the diffuse optical spectra (500-800 nm) using an optical fiber probe...
Computational Simulations for Infrared Laser Sealing and Cutting of Blood Vessels [0.03%]
红外激光血管封合和切割的计算模拟研究
Nicholas C Giglio,Nathaniel M Fried
Nicholas C Giglio
Blood vessel burst pressures were simulated and predicted for sealing and cutting of vessels in a two-step process, using low (
Intraoperative Label-Free Multimodal Nonlinear Optical Imaging for Point-of-Procedure Cancer Diagnostics [0.03%]
术中无标记多模非线性光学成像用于即时程序癌症诊断
Lingxiao Yang,Jaena Park,Marina Marjanovic et al.
Lingxiao Yang et al.
Intraoperative imaging in surgical oncology can provide information about the tumor microenvironment as well as information about the tumor margin. Visualizing microstructural features and molecular and functional dynamics may provide impor...
Precision-Microfabricated Fiber-Optic Probe for Intravascular Pressure and Temperature Sensing [0.03%]
用于血管压力和温度检测的精密微加工光纤探针
Radhika K Poduval,Joanna M Coote,Charles A Mosse et al.
Radhika K Poduval et al.
Small form-factor sensors are widely used in minimally invasive intravascular diagnostic procedures. Manufacturing complexities associated with miniaturizing current fiber-optic probes, particularly for multi-parameter sensing, severely con...
A hyperspectral imaging system for mapping haemoglobin and cytochrome-c-oxidase concentration changes in the exposed cerebral cortex [0.03%]
一种用于绘制暴露大脑皮层中血红蛋白和细胞色素氧化酶浓度变化的超光谱成像系统
Luca Giannoni,Frédéric Lange,Marija Sajic et al.
Luca Giannoni et al.
We present a novel hyperspectral imaging (HSI) system using visible and near-infrared (NIR) light on the exposed cerebral cortex of animals, to monitor and quantify in vivo changes in the oxygenation of haemoglobin and in cellular metabolis...
Photodynamic Priming Modulates Endothelial Cell-Cell Junction Phenotype for Light-activated Remote Control of Drug Delivery [0.03%]
光动力预处理可调节内皮细胞间连接表型以实现药物的光控释放
Collin T Inglut,Kelsey M Gray,Shruti Vig et al.
Collin T Inglut et al.
The blood-brain barrier (BBB) remains a major obstacle for drug delivery to the central nervous system. In particular, the tight and adherens junctions that join the brain capillary endothelial cells limit the diffusion of various molecules...