P L Pabst
P L Pabst
Functional reconstruction of the jaw bones using poly(l-lactide) mesh and autogenic particulate cancellous bone and marrow [0.03%]
使用聚左旋乳酸片和自体松质骨及骨髓粒植骨下颌骨功能重建
Y Kinoshita,M Kobayashi,S Fukuoka et al.
Y Kinoshita et al.
The goal of the reconstruction of jaw bone defects should be not only to recover deformities, but also to reconstruct the jaw with which the patient can perform normal functions. To achieve this purpose, it is essential that a method of pro...
Effect of the structure of bone morphogenetic protein carriers on ectopic bone regeneration [0.03%]
载骨形态发生蛋白载体的结构对其异位促骨再生的影响研究
M Yamamoto,K Kato,Y Ikada
M Yamamoto
To study the effect of the shape of carriers on bone regeneration, two biodegradable polymeric materials, a polyglycolide (PGA) nonwoven fabric and a gelatin hydrogel, were used as carriers of recombinant human bone morphogenetic protein-2 ...
K Tomihata,Y Ikada
K Tomihata
Carbodiimides were employed for cross-linking of gelatin through amide bond formation to avoid any foreign bond incorporation into the cross-linked gelatin molecules. Cross-linking of gelatin was performed not in aqueous solution but in the...
Early treatment of diabetes with porcine islets in a bioartificial pancreas [0.03%]
生物人工胰腺用于早期治疗糖尿病的猪胰岛细胞移植研究
T Maki,A P Monaco,C J Mullon et al.
T Maki et al.
Successful pancreas transplantation is an effective therapy for insulin-dependent diabetes mellitus (IDDM) but subjects patients to morbidity and mortality associated with chronic immunosuppression. Bioartificial pancreas devices containing...
H Iwata,N Morikawa,Y Ikada
H Iwata
Immunoisolation of islets of Langerhans (islets) by their enclosure in a filter to isolate them from the host immune system following implantation is a particularly attractive method for bioartificial pancreas. The filter should have excell...
The biologic action of parathyroid hormone-related Peptide on bone and cartilage cells [0.03%]
甲状旁腺激素相关肽对骨和软骨细胞的生物作用
N Amizuka,D Goltzman,H Ozawa
N Amizuka
Parathyroid hormone-related peptide (PTHrP) was originally identified as a factor inducing malignancy-associated hypercalcemia by activating a common receptor (PTH/PTHrP receptor) with PTH. Recently, PTHrP gene "knock-out" mice showed a for...
S Suzuki,K Matsuda,Y Nishimura et al.
S Suzuki et al.
Following the development of a bilayer acellular artificial skin by Yannas et al. which seemed unique with respect to spontaneous conversion of the inner collagen sponge into a dermis-like connective tissue layer, we started to develop an a...
S T Boyce
S T Boyce
Skin substitutes composed of cultured cells and biopolymers provide alternative materials for study of skin biology and pathology, treatment of skin wounds, safety testing of consumer products, and therapeutic delivery of gene products. Mos...
Surface roughness, porosity, and texture as modifiers of cellular adhesion [0.03%]
表面粗糙度、孔隙率和纹理对细胞黏附的调控作用
A F Recum,C E Shannon,C E Cannon et al.
A F Recum et al.
Substrate topography in the micrometer range is reviewed as a modifier of the response of cultured cells and of biocompatibility when implanted into tissues. Characterization methods for substrate topography are discussed, including scannin...