Phenotype gradation of human saphenous vein endothelial cells from cardiovascular disease subjects [0.03%]
来自心血管疾病供者的下肢隐静脉内皮细胞表型分级研究
C Krishna Prasad,K Jayakumar,Lissy K Krishnan
C Krishna Prasad
The highly organized histological architecture of the vascular wall and the specialized cellular phenotypes are perturbed in conditions such as atherosclerosis, restenosis, and hypertension. Alterations of endothelial cell (EC) phenotype in...
Evidence of vascular damage in dengue disease: demonstration of high levels of soluble cell adhesion molecules and circulating endothelial cells [0.03%]
登革热发病时血管损伤的证据：粘附分子和循环内皮细胞水平升高表明血管受损
José E Cardier,Betty Rivas,Egidio Romano et al.
José E Cardier et al.
Clinical evidence suggests that vascular damage plays a key role in the pathophysiology of dengue hemorrhagic fever (DHF). In this study, the authors tested this hypothesis by examining the levels of soluble intercellular adhesion molecule ...
Elevation of intracellular cAMP up-regulated thrombomodulin mRNA in cultured vascular endothelial cells derived from spontaneous type-II diabetes mellitus model rat [0.03%]
细胞内cAMP浓度升高上调自发型2型糖尿病模型大鼠来源血管内皮细胞株TMmRNA表达
Masanori Sunagawa,Seiji Shimada,Kazuhiko Hanashiro et al.
Masanori Sunagawa et al.
To investigate whether antihemostatic function of vascular endothelial cells (VECs) is changed in type-II diabetic model rats, the mRNA expressions of tissue-type and urokinase-type plasminogen activator (t-PA and u-PA), thrombomodulin (TM)...
Asymmetric subcellular distribution of glucose transporters in the endothelium of small contractile arteries [0.03%]
小收缩动脉内皮中葡萄糖转运蛋白的不对称亚细胞分布
N Gaudreault,D R L Scriven,E D W Moore
N Gaudreault
The authors have recently reported the presence and asymmetric distribution of the glucose transporters GLUT-1 to -5 and SGLT-1 in the endothelium of rat coronary artery (Gaudreault et al. 2004, Diabetologica, 47, 2081-2092). In the present...
Alkaline pH-induced extracellular regulated protein kinase activation in brain microvascular endothelial cells: differential effects of Tris and lowered CO2 [0.03%]
碱性pH值诱导脑微血管内皮细胞的细胞外调节蛋白激酶活化：Tris和降低二氧化碳的不同影响
Gregory T Motz,Mario Zuccarello,Robert M Rapoport
Gregory T Motz
As it was previously reported that Tris-elevated pH acutely activated extracellular regulated protein kinase (ERK) in rat aorta smooth muscle cells, this study tested whether this finding could be extended to endothelial cells and, moreover...
Role of CD7 expressed in lung microvascular endothelial cells as Fc receptor for immunoglobulin M [0.03%]
CD7在肺微血管内皮细胞上作为免疫球蛋白M的Fc受体的作用
Motoko Nishimura,Minoko Takanashi,Hitoshi Okazaki et al.
Motoko Nishimura et al.
Immunoglobulins (Igs) against anti-human white blood cells are putative contributors to the development of transfusion-related adverse effects, particularly transfusion-related acute lung injury (TRALI). Studies of Igs that are considered t...
High efficiency and long-term foreign gene expression in cultured liver sinusoidal endothelial cells by retroviral transduction [0.03%]
高效的长期肝窦状内皮细胞培养及外源基因表达
Jesus Paez,Ramon Montaño,Lorenzo Benatuil et al.
Jesus Paez et al.
The liver sinusoidal endothelial cells (LSECs) constitute a very specialized endothelium. Due to their multiple functions and privileged location in the liver, these cells constitute an excellent target for gene therapy. In this work, the a...
Activation of protein kinase A improves vascular endothelial dysfunction [0.03%]
蛋白激酶A的激活可改善血管内皮细胞功能障碍
Dhvanit I Shah,Manjeet Singh
Dhvanit I Shah
The study has been designed to investigate the effect of 8-Br-cAMP, an activator of protein kinase A (PKA), in diabetes mellitus- and hyperhomocysteinemia-induced vascular endothelial dysfunction. Streptozotocin (55 mg kg-1, i.v.) and methi...
Inhibition of endothelial cell proliferation, in vitro angiogenesis, and the down-regulation of cell adhesion-related genes by genistein. Combined with a cDNA microarray analysis [0.03%]
染料木素抑制血管内皮细胞增殖、体外形成血管及降低与细胞黏附相关基因的表达：结合cDNA微阵列分析
Meihua Piao,Daisuke Mori,Tosimi Satoh et al.
Meihua Piao et al.
Antiangiogenesis is presently one of the powerful strategies for treating cancer, and endothelial cells play a pivotal role in the process of angiogenesis. Genistein, a tyrosine kinase inhibitor, a major isoflavone plentiful in soybeans, is...
Concanavalin A, but not glycated albumin, increases subendothelial deposition of von Willebrand factor in vitro [0.03%]
构巢酵母凝集素而非糖化白蛋白可增加体外内皮下von Willebrand因子沉积
Konstantin Nizheradze
Konstantin Nizheradze
Diabetes is associated with augmentation of prothrombogenic von Willebrand factor (vWF) content in plasma. Earlier, the author and colleagues have shown that high glucose and insulin do not appreciably influence deposition of vWF into the s...