cDNA cloning and some additional peptide characterization of a single-chain vascular apoptosis-inducing protein, VAP2 [0.03%]
血管凋亡诱导蛋白VAP2的cDNA克隆及部分肽段分析
Shinako Masuda,Hiroki Maeda,Jun Ying Miao et al.
Shinako Masuda et al.
Vascular apoptosis-inducing proteins (VAPs) from hemorrhagic snake venom are apoptosis-inducing toxins targeting vascular endothelial cells. Well-characterized VAPs consist of disulfide-bridged double chains (ddVAPs). The authors previously...
Improved identification of endothelial erosion by simultaneous detection of endothelial cells (CD31/CD34) and platelets (CD42b) [0.03%]
同时检测内皮细胞(CD31/CD34)和血小板(CD42b)以改进对内皮损伤的识别
Mikko I Mäyränpää,Julio C Reséndiz,Hanna M Heikkilä et al.
Mikko I Mäyränpää et al.
Loss of endothelial cells (ECs) with ensuing exposure of thrombogenic subendothelial surface is a common cause of thromboembolic complications in atherosclerotic arteries. Thus, endothelial denudation has emerged as a major contributor to t...
Associations between systemic and cerebral endothelial impairment determined by cerebrovascular reactivity to L-arginine [0.03%]
L-精氨酸脑血管反应性决定的系统性和脑内皮功能障碍的关系
Janja Pretnar-Oblak,Miso Sabovic,Marjan Zaletel
Janja Pretnar-Oblak
The relationships between cerebral and systemic endothelial (dys)function and between cerebral (dys)function and intima-media thickness (IMT) of carotid arteries in patients and healthy volunteers have not yet been clarified. In order to ex...
Effects of beta-endorphin on endothelial/monocytic endothelin-1 and nitric oxide release mediated by mu1-opioid receptors: a potential link between stress and endothelial dysfunction? [0.03%]
β-内啡肽通过μ1型阿片受体介导的单核细胞/内皮素-1和一氧化氮释放对内皮功能影响的作用机制：应激与血管内皮功能障碍之间的潜在联系？
U Wilbert-Lampen,A Trapp,S Barth et al.
U Wilbert-Lampen et al.
Observations have been made linking the presence of psychosocial factors associated with elevated beta-endorphin concentrations with atherosclerosis. In this study, the authors assume an important role of the stress hormone beta-endorphin i...
Mesenchymal stem cells induce endothelial activation via paracine mechanisms [0.03%]
内皮细胞通过旁分泌机制活化间质干细胞
Dennis Ladage,Klara Brixius,Caroline Steingen et al.
Dennis Ladage et al.
Mesenchymal stem cells (MSCs) are bone marrow-derived, pluripotent cells that possess the ability to transdifferentiate into various mesenchymal tissues such as bone, endothelium, and (heart) muscle. Therefore, these cells may provide a the...
Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromes [0.03%]
糖尿病患者和非糖尿病患者的急性冠脉综合征期间金属蛋白酶-2和-9的变化
Giuseppe Derosa,Arrigo F G Cicero,Filippo Scalise et al.
Giuseppe Derosa et al.
The authors hypothesized that matrix metalloproteinase (MMP)-2, -9, and tissue inhibitor metalloproteinase (TIMP)-1, -2 would be abnormal in acute coronary syndromes (ACSs). MMP-2, -9, and TIMP-1, -2 plasma levels were measured in diabetic ...
Immortalization and characterization of porcine ventricular endocardial endothelial cells [0.03%]
猪心室内皮细胞的传代培养及其鉴定
Leena Kuruvilla,Santhoshkumar T R,Chandrasekharan Cheranellore Kartha
Leena Kuruvilla
Endocardial endothelial cells (EECs), which form the inner lining of the cavities of the heart, are a distinct cell population whose dysfunction can be critical in pathological conditions of heart. Insights into the role and organization of...
A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration [0.03%]
脑内皮细胞中的一种新型溶血磷脂和pH敏感受体GPR4调节单核细胞的迁移现象
Fei Huang,Dolly Mehta,Sanda Predescu et al.
Fei Huang et al.
Abundant evidence documents the highly proinflammatory actions of lysophosphatidylcholine (LPC). Further, LPC, found in high amounts in oxidized low-density lipoprotein (LDL), is implicated as an atherogenic factor. In endothelial cells, LP...
Elevated glucose attenuates agonist- and flow-stimulated endothelial nitric oxide synthase activity in microvascular retinal endothelial cells [0.03%]
高糖通过抑制内皮型一氧化氮合酶活性削弱微血管视网膜内皮细胞功能
Paul Connell,Tony Walshe,Gail Ferguson et al.
Paul Connell et al.
Impaired vasoactive release of opposing vasodilator and vasoconstrictor mediators due to endothelial dysfunction is integral to the pathogenesis of diabetic retinopathy. The aim of this study was to determine the effect of hyperglycemia on ...
Elodie Mordelet,Heather A Davies,Philippa Hillyer et al.
Elodie Mordelet et al.
Leukocyte migration across vascular endothelium is mediated by chemokines that are either synthesized by the endothelium or transferred across the endothelium from the tissue. The mechanism of transfer of two chemokines, CXCL10 (interferon ...