Molecular recognition properties of water-soluble Prism[5]arene towards drugs of abuse [0.03%]
水溶性Prism[5]arene对滥用药物分子识别性质的研究
Gurpreet Kaur,Emmanuel A Bazan-Bergamino,Canjia Zhai et al.
Gurpreet Kaur et al.
We report our study of the binding of a water soluble prism[5]arene (WPr[5]) toward a panel of 11 drugs of abuse by a combination of 1H NMR spectroscopy, isothermal titration calorimetry (ITC), and molecular modelling. 1H NMR spectroscopy s...
Tetrachloroanthracene Walled Glycoluril Dimer Undergoes Self-Association and 1:1, 2:2, and 1:3 Host•Guest Binding [0.03%]
四氯苊大环的甘油尿二聚物guest分子的自缔合及1:1、2:2和1:3主客体包合作用研究
Noah Hornstein,Suvenika Perera,Alok Shaurya et al.
Noah Hornstein et al.
We report the design, synthesis and characterization of a tetrachloroanthracene walled methylene bridged glycoluril dimer (H1). According to 1H NMR spectroscopy and symmetry considerations we formulate H1 as a C 2v -symmetric monomer in DMS...
Synthesis of tyramine bis(dipicolylamine), a versatile synthetic receptor scaffold for oxyanion recognition [0.03%]
用于氧阴离子识别的高效价多吡唑胺钛胲受体合成
Jon Chiaramonte,Hunter B D Cheney,Bradley D Smith
Jon Chiaramonte
Zinc-coordinated bis(dipicolylamine) (ZnBDPA) and its phenoxy derivative (ZnPhenoxyBDPA) are well-known as synthetic receptors with strong affinity for oxyanions, especially phosphorylated biomolecules. Over the last two decades, these synt...
Fluorescent cyclopropyl ester probes are efficiently cleaved by endogenous carboxylesterase in mouse blood: implications for preclinical fluorescence imaging [0.03%]
荧光环丙基酯探针可被小鼠血液中的内源性羧酸酯酶有效裂解：对临床前荧光成像的意义
Hailey S Sanders,Kirk M Atkinson,Bradley D Smith
Hailey S Sanders
Prior studies have shown that fluorescent molecular probes based on cyclopropyl esters are good substrates for butyrylcholinesterase (BChE) which is a biomarker of several human diseases. We tested two fluorescent cyclopropyl ester derivati...
Corinne L D Gibb,André J Hebert,Yahya A Ismaiel et al.
Corinne L D Gibb et al.
Octa-acid 1 is a water-soluble deep-cavity cavitand devised in our labs that has found utility in a number of research groups. The host has been used to investigate hydrophobic solvation and Hofmeister effects, control photophysical and phy...
NASC 2023: Showcasing Diversity in North American Supramolecular Chemistry [0.03%]
2023年北美超分子化学的多样性：NASC会议展示
Nathalie Busschaert,Clifton J Stephenson,Kristin Bowman-James et al.
Nathalie Busschaert et al.
Diversity in supramolecular chemistry can showcase itself in many ways. This includes the diversity of thought and topics covered in research (from fundamental science to applications in biology and materials), as well as the diversity of p...
Dynamic Light Scattering - an all-purpose guide for the supramolecular chemist [0.03%]
动态光散射-超分子化学家的全方位指南
Anthony Wishard,Bruce C Gibb
Anthony Wishard
Dynamic light scattering (DLS) is a useful tool for the study of the solution-based behavior of colloids and molecular assemblies. The aim of this methods paper is to provide perspective on how this technique can be used by supramolecular c...
Kimberly G Brady,Bingqing Liu,Xiaopeng Li et al.
Kimberly G Brady et al.
We report preparation of (bis)aniline ligand 4 which contains a central viologen binding domain and its subcomponent self-assembly with aldehyde 5 and Fe(OTf)2 in CH3CN to yield tetrahedral assembly 6. Complexation of ligand 4 with CB[7] in...
Ming Cheng,Lyle Isaacs
Ming Cheng
We report the design and synthesis of the acyclic cucurbit[n]uril-β-cyclodextrin chimeric host H1. The goal of the study is to deepen the cavity of the receptor to allow β-CD complexation of moieties on the guest (especially fentanyl) tha...
Eman A Akam,Ritika Gautam,Elisa Tomat
Eman A Akam
Sirtinol, a Schiff base derived from 2-hydroxy-1-naphthaldehyde, is an inhibitor of sirtuin proteins, a family of deacetylases active in gene regulation and relevant to the study of cancer growth. The formation of copper(II) and zinc(II) co...