c-myb and growth control [0.03%]
c-myb与生长调控
B Calabretta,N C Nicolaides
B Calabretta
The available evidence indicates that c-myb plays an important role in the proliferation of hematopoietic cells and in those nonhematopoietic cell types in which c-myb is expressed. A critical aspect in the regulation of c-myb expression re...
J S Zlatanova,K E van Holde
J S Zlatanova
The existence of a supermolecular structure in the eukaryotic nucleus, involving loops of chromatin attached at irregularly spaced points to the nuclear matrix, is now well established. Quite a bit is known concerning the DNA sequences invo...
J L Hamlin
J L Hamlin
Mammalian origins of replication are scattered at about 100-kb intervals along each chromosomal DNA fiber. It is not known whether origins are genetically defined sequences analogous to those that control initiation of replication in microo...
D Castanotto,J J Rossi,J O Deshler
D Castanotto
Several naturally occurring ribozymes have now been well characterized with respect to their in vivo and in vitro activities. Through detailed biochemical and genetic analyses, it has become possible to alter the substrate specificity of ea...
C W Anderson,S P Lees-Miller
C W Anderson
The DNA-activated protein kinase (DNA-PK) is a nuclear serine/threonine protein kinase that phosphorylates DNA-binding proteins, including several transcription factors. DNA-PK is one of a very few enzymes known to be regulated through inte...
Gene expression, signal transduction and tissue-specific biomineralization during mammalian tooth development [0.03%]
哺乳动物牙齿发育过程中的基因表达、信号转导和组织特异性生物矿化现象
H C Slavkin,C C Hu,Y Sakakura et al.
H C Slavkin et al.
Tooth development provides a paradigm for intrinsic molecular controls for cell- and extracellular matrix (ECM)-mediated biomineralization. The intent of this review is to evaluate the sequential timing and positional information prerequisi...
DUBR/miR-17-3p/TFRC/HO-1 Axis Promotes the Chemosensitivity of Multiple Myeloma [0.03%]
DUBR/miR-17-3p/TFRC/HO-1轴促进多发性骨髓瘤的化疗敏感性
Long non-coding RNAs (lncRNAs) are intensively involved in the pathogenesis of multiple myeloma (MM). The purpose of this study was to investigate the potentials of DUBR in MM. Gene expression was determined using RT-qPCR and western blot. ...