Ectopic Expression of TIGIT in Lung Adenocarcinoma and Its Clinical Significance [0.03%]
肺腺癌中TIGIT的异位表达及其临床意义
Shuyan He,Ning Qian,Shujuan Ren et al.
Shuyan He et al.
This study aimed to investigate the T cell immunoreceptor with ITIM and Ig domains (TIGIT) expression in lung adenocarcinoma (LUAD). TIGIT expression was measured by western blot, reverse transcription quantitative polymerase chain reaction...
MIR222HG/LIN28B/ATG5 Axis Drives M2 Macrophage Polarization and Proliferation of Hepatocellular Carcinoma Cells [0.03%]
MIR222HG/LIN28B/ATG5轴驱动M2巨噬细胞极化及肝癌细胞增殖
Xiao Zuo,Yan Shao,Yuhang Liang et al.
Xiao Zuo et al.
Long non-coding RNAs (lncRNAs) are involved in the pathogenesis of hepatocellular carcinoma (HCC). This study aimed to investigate the potential of MIR222HG in HCC. HCC cells were co-cultured with U937 cells. Gene expression was determined ...
UTP23 Is a Promising Prognostic Biomarker and Is Associated with Immune Infiltration in Breast Cancer [0.03%]
UTP23是乳腺癌预后生物标志物，并与免疫浸润相关
Jindong Li,Siman Xie,Benteng Zhang et al.
Jindong Li et al.
Breast cancer is one of the malignant tumors with a high incidence and mortality rate among women worldwide, and its prevalence is increasing year by year, posing a serious health risk to women. UTP23 (UTP23 Small Subunit Processome Compone...
Pan-Cancer Analysis of the LOX Family Reveals that LOX Affects Tumor Prognosis by Affecting Immune Infiltration [0.03%]
泛癌分析LOX家族揭示LOX通过影响免疫浸润影响肿瘤预后
Chunlong Zheng,Yan Chu,Nian Zhang et al.
Chunlong Zheng et al.
The lysyl oxidase (LOX) gene family encodes for a group of copper-dependent enzymes that play a crucial role in the cross-linking of collagen and elastin fibers in the extracellular matrix (ECM). Dysregulation of LOX gene expression has bee...
Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis [0.03%]
LPCAT3的甲基化调控通过调节ACSL4抑制软骨细胞铁死亡从而改善骨关节炎
Kaken Habaxi,Wei Wang,Maimaitiaili Taximaimaiti et al.
Kaken Habaxi et al.
With the increasing aging population in China, the incidence rate of knee osteoarthritis is expected to rise annually. Therefore, we conducted a study to investigate the crucial role of LPCAT3 in osteoarthritis and its underlying mechanisms...
Novel Pathways between Invasiveness Modulators in Breast Cancer Single Cells [0.03%]
调控乳腺癌单细胞侵袭性的新型途径研究
George L Eliceiri
George L Eliceiri
Individual cells are known to behave differently than their whole populations of cells. The present work focused on proteins that control cancer invasiveness. Individual Dicer siRNA knockdown of HER4, CDC42, and E-cadherin decreased MMP1 mR...
Bromodomain Proteins Epigenetically Regulate the Mitotically Associated lncRNA MANCR in Triple Negative Breast Cancer Cells [0.03%]
溴结构域蛋白通过表观遗传调控三阴性乳腺癌细胞中与有丝分裂相关长链非编码RNA MANCR的表达
Kirsten M Tracy,Shannon Prior,Willem T Trowbridge et al.
Kirsten M Tracy et al.
Long non-coding RNA (lncRNA)-mediated control of gene expression contributes to regulation of biological processes that include proliferation and phenotype, as well as compromised expression of genes that are functionally linked to cancer i...
Molecular Expression and Prognostic Implications of Krüppel-Like Factor 3 (KLF3) in Clear Cell Renal Cell Carcinoma [0.03%]
Krüppel样因子3(KLF3)在透明细胞肾细胞癌中的分子表达及其预后意义
Bin Wan,Wensheng Zhang,Xinxi Deng et al.
Bin Wan et al.
A major subtype of renal cancer is clear cell renal cell carcinoma (ccRCC). Krüppel-like factor 3 (KLF3) dysfunction is also revealed leading to poor prognosis in multiple cancer types. However, dysregulation and molecular dynamics of KLF3...
lncRNA799/TBL1XR1/ZEB1 Axis Forms a Feedback Loop to Promote the Epithelial-Mesenchymal Transition of Cervical Cancer Cells [0.03%]
长链非编码RNA799/TBL1XR1/ZEB1轴形成正反馈回路以促进宫颈癌细胞的上皮间质转化
Lingmin Liao,Peng Huang,Jiali Zhao et al.
Lingmin Liao et al.
Cervical cancer is a common malignancy among women worldwide. Long non-coding RNAs (lncRNAs) are frequently involved in the pathogenesis of cervical cancer. Therefore, the present study aimed to investigate the potentials of lncRNA799 in ce...
Sidra Anwar,Bilal Ahmed,Muhammad Imran Qadir
Sidra Anwar
In this review, there is a complete description of the classes of arboviruses, their evolutionary process, virus characterization, disease transmission methods; it also describes about the vectors involved in transmission and their mood of ...