HDAC1-Mediated Downregulation of NEU1 Exacerbates the Aggressiveness of Cervical Cancer [0.03%]
组蛋白去乙酰化酶1介导的神经氨酸苷酶1低表达促进宫颈癌恶性进展
Nanzi Xie,Sisi Mei,Changlan Dai et al.
Nanzi Xie et al.
HDAC1 functions as an oncogene in multi-type cancers. This study aimed to investigate the roles of histone deacetylase 1 (HDAC1) in cervical cancer (CC). mRNA expression was determined using reverse transcription quantitative polymerase cha...
miR-26b-5p Affects the Progression of Acute Myeloid Leukemia by Regulating the USP48-Mediated Wnt/β-Catenin Pathway [0.03%]
微RNA-26b-5p通过调节泛素特异性肽酶48介导的Wnt/β-连环蛋白信号通路影响急性髓系白血病的发展
Yu Xie,Lin Tan,Kun Wu et al.
Yu Xie et al.
Acute myeloid leukemia (AML) is a highly heterogeneous disease. Exploring the pathogenesis of AML is still an important topic in the treatment of AML. The expression levels of miR-26b-5p and USP48 were measured by qRT-PCR. The expression le...
Prototype Salivary Assay for Quantification of Two Biomarkers for In Vitro Diagnosis of Endometriosis [0.03%]
用于体外诊断子宫内膜异位症的两种生物标志物的唾液原型测定法
Pietro Giulio Signorile,Sabrina Dominici,Rosa Viceconte et al.
Pietro Giulio Signorile et al.
Endometriosis, a very common disease in women, is characterized by endometrial structures outside the uterine cavity. The lack of a reliable noninvasive diagnostic test and the often nonspecific symptoms of this pathology are responsible fo...
microRNA-486-5p Regulates DNA Damage Inhibition and Cisplatin Resistance in Lung Adenocarcinoma by Targeting AURKB [0.03%]
靶向AURKB的microRNA-486-5p通过调节DNA损伤抑制和顺铂耐药性影响肺腺癌的发展
Gaozhong Sun,Kewei Ni,Jian Shen et al.
Gaozhong Sun et al.
Lung adenocarcinoma (LUAD) severely affects human health, and cisplatin (DDP) resistance is the main obstacle in LUAD treatment, the mechanism of which is unknown. Bioinformatics methods were utilized to predict expression and related pathw...
KRT6A Inhibits IL-1β-Mediated Pyroptosis of Keratinocytes via Blocking IL-17 Signaling [0.03%]
KRT6A通过阻断IL-17信号抑制角质形成细胞中的炎性半胱天冬酶介导的细胞焦亡
Yuan Li,Qi Wu
Yuan Li
Keratin 6A (KRT6A) is involved in the pathogenesis of various skin diseases. However, the reports on the roles of KRT6A in atopic dermatitis (AD) are limited. This study aimed to investigate the potentials of KRT6A in AD. mRNA levels were d...
Pathogens in Crohn's Disease: The Role of Adherent Invasive Escherichia coli [0.03%]
克罗恩病中的病原体：黏附侵袭大肠杆菌的作用
Gaetano Iaquinto,Vera Rotondi Aufiero,Giuseppe Mazzarella et al.
Gaetano Iaquinto et al.
In Crohn's disease (CD), gut dysbiosis is marked by the prevalence of pathogenic bacterial species. Although several microbes have been reported as risk factors or causative agents of CD, it is not yet clear which is the real trigger of the...
Down-Regulation of CPEB4 Alleviates Preeclampsia through the Inhibition of Ferroptosis by PFKFB3 [0.03%]
CPEB4的下调通过PFKFB3抑制铁死亡从而缓解子痫前期
Jiao Song,Hailan Yang
Jiao Song
Gestational diabetes mellitus (GDM) complicated with preeclampsia can lead to polyhydramnios, ketosis. Herein, we explored that CPEB4 in cancer progression of preeclampsia and its underlying mechanism. All the serum samples were collected f...
DLEU2/EZH2/GFI1 Axis Regulates the Proliferation and Apoptosis of Human Bone Marrow Mesenchymal Stem Cells [0.03%]
DLEU2/EZH2/GFI1轴调节人骨髓间充质干细胞的增殖和凋亡
Qing Yao,Xuezhi He,Jing Wang et al.
Qing Yao et al.
Long non-coding RNAs (lncRNAs) has become a vital regulator in the pathogenesis of osteoporosis (OP). This study aimed to investigate the role of lncRNA DLEU2 in the development of proliferation and apoptosis of human bone marrow mesenchyma...
KIF20B Correlates with LUAD Progression and Is an Independent Risk Factor [0.03%]
KIF20B与LUAD进展相关，并是一个独立的风险因素
Jianye Yang,Liang Xu,Xiaoliang Han
Jianye Yang
Objective: Kinesin family proteins (KIFs) play crucial roles in human tumorigenesis and progression. This study aimed to investigate the expression and association of Kinesin family member 20B (KIF20B) with lung adenocarc...
Differential Expression of KIF18B in Gastric Cancer and Its Role in Chemotherapy Sensitivity [0.03%]
KIF18B在胃癌中的差异表达及其在化疗敏感性中的作用
Li-Hong Gan,Ling Yao,Jin-Hua Yan et al.
Li-Hong Gan et al.
Gastric cancer (GC) is a main cause of cancer death in the world, and improving the chemotherapy sensitivity can enhance the chemotherapy efficacy of GC. The study objective is to explore the differential KIF18B expression in GC and its eff...