KDM6A Promotes Angiogenesis, Migration, and Invasion of Pancreatic Cancer by Activating LAMP3 [0.03%]
KDM6A通过激活LAMP3促进胰腺癌血管生成、迁移和侵袭
Sunfu Fan,Liang Xu,Dafei Xie et al.
Sunfu Fan et al.
Lysine demethylase 6A (KDM6A) is abnormally expressed in various cancer. This study aimed to investigate the potential of KDM6A in pancreatic cancer (PC). mRNA expression was calculated by reverse transcription quantitative real-time polyme...
Palmdelphin Inhibits Ovarian Cancer Cell Stem Specification via Downregulating Ring Finger Protein 145 [0.03%]
棕榈德尔菲宁通过下调环指蛋白145抑制卵巢癌干细胞特性分化
Nanzi Xie,Sisi Mei,Changlan Dai et al.
Nanzi Xie et al.
This study aimed to investigate the roles of PALMD in ovarian cancer. mRNA expression was detected using RT-qPCR. The aldehyde dehydrogenase (ALDH) activity and biomarkers of ovarian cancer stem cells were determined using flow cytometry. T...
MS4A3 Promotes the Chemosensitivity of Lung Cancer via THAP1/EGFR Pathways [0.03%]
MS4A3通过THAP1/EGFR通路促进肺癌的化疗敏感性
Zhihui Duan
Zhihui Duan
MS4A3 functions as a tumor suppressor in multiple cancer types. However, the roles of MS4A3 in lung cancer are still unknown. Therefore, this study aims to investigate the potentials of MS4A3 in lung cancer. Reverse transcription quantitati...
J Toner,Johnathan A R Gordon,H Greenyer et al.
J Toner et al.
The RUNX2 transcription factor was discovered as an essential transcriptional regulator for commitment to osteoblast lineage cells and bone formation. Expression of RUNX2 in other tissues, such as breast, prostate, and lung, has been linked...
Cancer Cell-Type-Dependent Modifications of Metastatic Parameters by SLIT2-ROBO1 and RHOA cAMP Signaling in Response to TGFβ1 and FGF2 [0.03%]
SLIT2-ROBO1和RHOAcAMP信号传导途径通过响应TGFβ1和FGF2对转移参数进行癌细胞类型依赖性调节
Quratulain Amjad,Gary S Stein,Andre J van Wijnen et al.
Quratulain Amjad et al.
The epithelial to mesenchymal transition (EMT) is a multistep process involving structural and functional alterations that are required for cancer metastasis, as well as loss of epithelial markers (e.g., E-cadherin/CDH1) and gain of mesench...
Alterations in the Relationship between Cells and Their Context Is the Basis of a Pathological Condition [0.03%]
细胞及其所处环境间关系的改变是病理状态的基础
Domenico Ribatti
Domenico Ribatti
Pathological conditions can be considered as alterations in the relationships between the cells of different tissues and organs and the microenvironment that surrounds them, primarily the different constituents of the extracellular matrix. ...
Electroacupuncture Alleviates Parkinson's Disease by Promoting METTL9-Catalyzed Histidine Methylation of Nuclear Factor-κВ [0.03%]
电针通过促进METTL9介导的核因子-кВ组蛋白精氨酸甲基化缓解帕金森病
Xiang Zhou,Liang Zhou,Jiayi Sun et al.
Xiang Zhou et al.
This study aimed to investigate the effects of electroacupuncture (EA) treatment on Parkinson's disease (PD). 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration was used establish PD mice model. The number of neurons is dete...
Transplantation of miR-193b-3p-Transfected BMSCs Improves Neurological Impairment after Traumatic Brain Injury through S1PR3-Mediated Regulation of the PI3K/AKT/mTOR Signaling Pathway [0.03%]
miR-193b-3p基因修饰的骨髓间充质干细胞移植通过S1PR3介导调节PI3K/AKT/mTOR信号通路改善颅脑损伤后神经功能缺陷
Yinghong He,Yuanmou Li,Yan Zhang et al.
Yinghong He et al.
The aim of the present study was to explore the molecular mechanisms by which miR-193b-3p-trans-fected bone marrow mesenchymal stem cells (BMSCs) transplantation improves neurological impairment after traumatic brain injury (TBI) through sp...
Expression and Clinicopathological Significance of Extracellular Matrix Remodeling Markers in Esophageal Squamous Carcinoma [0.03%]
食管鳞癌的基质重塑标志物表达及其临床病理意义分析
Zhiqin Fan,Fei Chen,Yingmin Liu et al.
Zhiqin Fan et al.
Esophageal squamous cell carcinoma (ESCC) is a common malignancy of the gastrointestinal tract with a single therapeutic option and a lack of effective clinical therapeutic biomarkers. Extracellular matrix (ECM) remodeling plays a pro-carci...
A MicroRNA Approach to Evaluating Elevated Prostate Cancer Risk in Cancer-Free Men [0.03%]
用于评估无癌症男性前列腺癌高风险的微小核糖核酸方法
Scott D Perrapato,Nicholas H Farina,Adrian N Berg et al.
Scott D Perrapato et al.
Objective criteria are required for prostate cancer (PCa) risk assessment, treatment decisions, evaluation of therapy, and initial indications of recurrence. Circulating microRNAs were utilized as biomarkers to distinguish PCa patients from...