Exosomal circ_001860 Promotes Colorectal Cancer Progression through the miR-582-5p/ZEB1 Axis [0.03%]
外泌体circ_001860通过miR-582-5p/ZEB1轴促进结直肠癌进展
Weizhen Huang,Jun Li,Siwei Zhou et al.
Weizhen Huang et al.
Extensive research has recently been conducted to investigate the regulating impact of exosomal circular RNAs (circRNAs) in throughout the development of multiple malignancies. Nevertheless, there is still much to learn about the biological...
Glycosaminoglycan Adenogenesis Factors: Immunohistochemical Expression in Endometriosis Tissues Compared with the Endometrium [0.03%]
糖胺聚糖卵巢生成因子在子宫内膜异位症组织中的免疫组化表达与子宫内膜的对比研究
Pietro Giulio Signorile,Alfonso Baldi,Rosa Viceconte et al.
Pietro Giulio Signorile et al.
Endometriosis is a chronic inflammatory pathology estrogen-dependent. It is a condition affecting 5%-10% of women of reproductive age worldwide. Recent evidence indicating an embryological origin of endometriosis has provided new insights i...
Identification of a Risk Signature and Immune Cell Infiltration Based on Extracellular Matrix-Related lncRNAs in Lung Adenocarcinoma [0.03%]
基于细胞外基质相关长链非编码RNA的肺腺癌风险标志物鉴定及免疫细胞浸润分析
Moyuan Zhang,Tianqi Cen,Shaohui Huang Huang et al.
Moyuan Zhang et al.
Lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths globally, with late diagnoses often resulting in poor prognoses. The extracellular matrix (ECM) plays a crucial role in cancer cell processes. Using big data from RNA-...
Review of the Bioactivities and Mechanisms of Fungus Extracts and Compounds in Colon Cancer [0.03%]
真菌提取物及化合物抗结肠癌活性及机制研究进展
Xinze Liu,Kaijing Sun,Lin Feng et al.
Xinze Liu et al.
Colon cancer, a malignant tumor caused by a malignant lesion of the colonic mucosal epithelium, has seen a high incidence in recent years. Fungi contain polysaccharides, terpenes, flavonoids, and other chemical components, and the diversity...
Curcumin-carbon dots suppress periodontitis via regulating METTL3/IRE1α signaling [0.03%]
姜黄素-碳点通过调节METTL3/IRE1α信号抑制牙周炎
Ling Li,Yueyan Wang,Lang Gao et al.
Ling Li et al.
This study aimed to investigate the effects of curcumin-carbon dot conjugates (CUR-CD) on periodontitis. Porphyromonas gingivalis lipopolysaccharide (LPS) was used to establish periodontitis mode in vivo and in vitro. Histological analysis ...
ATF4 Exacerbates Cerebral Infarction-Induced Sensory Dysfunction via HDAC1/DNMT1/GPX4 Signaling [0.03%]
ATF4通过HDAC1/DNMT1/GPX4信号通路加剧脑梗死引起的的感觉功能障碍
Bingtuan Lu,Ninghui Mu,Pu Li et al.
Bingtuan Lu et al.
Cerebral infarction is the main cause of death and long-term disability worldwide. Neuronal degeneration and limp sensory dysfunction are the secondary damages induced by cerebral infarction. This study aimed to investigate the roles of act...
DNMT1-Dependent DNA Methylation of lncRNA FTX Inhibits the Ferroptosis of Hepatocellular Carcinoma [0.03%]
DNMT1介导的长链非编码RNAFTX甲基化抑制肝细胞癌铁死亡
Sunfu Fan,Chaodan Shao,Shengnan Jia et al.
Sunfu Fan et al.
Hepatocellular carcinoma (HCC) is one of the most malignant solid tumors worldwide. Long non-coding RNAs (lncRNAs) are the key factor in the pathogenesis of HCC. This study aimed to investigate the roles of lncRNA FTX transcript, XIST regul...
Distribution of Antibiotic-Resistant Genes in Intestines of Infants and Influencing Factors [0.03%]
婴儿肠道抗生素抗性基因分布及影响因素分析
Yu-Chun Wang,Tie-Min Jiang,Lei Mo et al.
Yu-Chun Wang et al.
The objective of this study is to assess the prevalence of antibiotic-resistant genes (ARGs) in the intestines of infants and the factors affecting their distribution. Breast milk and infant stool samples were collected from nine full-term,...
FTO-Mediated m6A Modification of FTH1 Inhibits Ferroptosis of Neurons in Neonatal Cerebral Hypoxic Ischemia [0.03%]
FTO介导的FTH1m6A修饰抑制新生儿脑缺氧缺血神经元铁死亡
Yanhong Chen,Jia Huang
Yanhong Chen
FTO alpha-ketoglutarate dependent dioxygenase (FTO) is aberrantly expressed in brain disorders. However, the roles of FTO in neonatal hypoxic-ischemic brain injury (HIE) are still unclear. This study aims to investigate the potential of FTO...
Foxm1-Mediated Transcriptional Inactivation of NLRP3 Inflammasome Promotes Immunosuppression in Cervical Cancer [0.03%]
FoxM1介导的NLRP3炎症小体转录抑制促进宫颈癌免疫抑制
Weipeng Ji,Yang Jin,Wen Jiang
Weipeng Ji
Foxm1 functions as an oncogene in multiple human malignancies, including cervical cancer. However, the potential of Foxm1 in the tumor microenvironment (TME) is still unknown. The purpose of the present study is to investigate the role of F...