Multispectral Imaging of Intrinsic Metabolic Fluorophores: Detection of Human Breast Cancer in Fresh Ex Vivo Specimens [0.03%]
内源代谢荧光素的多光谱成像技术：检测新鲜离体样本中的人乳腺癌
Gary E Carver,Mark D Entwistle,Prachi N Ghule et al.
Gary E Carver et al.
A growing number of women develop breast cancer and require surgery. Many lumpectomies lead to follow-up procedures after the initial surgery. Advanced scanning technologies have reduced the number of second and third surgeries, but only by...
TRIP13 Is a Potential Prognostic Marker and Therapeutic Target for Endometrial Cancer [0.03%]
TRIP13是子宫癌的潜在预后标志物和治疗靶点
Zengzhen Lai,Chaolin Li
Zengzhen Lai
Uterine corpus endometrial carcinoma (UCEC) is a prevalent malignancy within the female reproductive system, with a rising global incidence. Although thyroid hormone receptor interacting protein 13 (TRIP13) has been implicated in various tu...
Identification and Validation of a Novel Prognostic Signature of Gastric Cancer Based on Seven Complement System-Related Genes: An Integrated Analysis [0.03%]
基于七种补体系统相关基因的胃癌新型预后特征识别与验证：整合分析
Jiaxing Zhang,Weijing Zhu,Shengrui Yang et al.
Jiaxing Zhang et al.
The complement system (CS) is linked to the progression of gastric cancer (GC), which has a high mortality rate, though its mechanisms in GC remain unclear. This study aims to identify CS-related prognostic genes with causal links to GC, an...
METTL17-Mediated Inhibition of M1 Macrophage Polarization Alleviates the Progression of Ankylosing Spondylitis [0.03%]
METTL17介导的M1巨噬细胞极化抑制缓解强直性脊柱炎进程
Jiang-Tao Lv,Ying-Ying Zhang,Shao-Qi Tian et al.
Jiang-Tao Lv et al.
RNA methylation is involved in the pathogenesis of ankylosing spondylitis (AS). This study aimed to investigate the potentials of METTL17 in AS. mRNA expression was detected using RT-qPCR. RNA methylation was detected using MeRIP assay. Pro...
Propofol Protects against Pyroptosis of Photoreceptors in Subretinal Hemorrhage via Regulating SIRT6/NLRP3 Signaling [0.03%]
丙泊酚通过调节SIRT6/NLRP3信号传导保护视网膜下出血中的光感受器免受焦亡的伤害
Huihui Wang,Limei Zhang,Xiaoli Bai et al.
Huihui Wang et al.
Subretinal hemorrhage-induced neurotoxicity is a key cause of vision loss in age-related macular degeneration (AMD). The purpose of this study is to investigate the effects of Propofol on neurotoxicity. Oxygen glucose deprivation (OGD) was ...
Prognostic Values of Homocysteine and Potassium Levels in Acute Ischemic Stroke Patients after Intravenous Thrombolysis with Recombinant Tissue-Type Plasminogen Activator [0.03%]
静脉注射重组组织型纤溶酶原激活剂治疗急性缺血性卒中患者同型半胱氨酸和钾水平的预后价值
Keliang Li,Min Xu,Yun Zhang et al.
Keliang Li et al.
Abnormal levels of homocysteine (Hcy) and potassium are associated with poor prognosis of patients with ischemic stroke. Nonetheless, the roles Hcy and potassium in the prognosis of patients with acute ischemic stroke (AIS) receiving intrav...
CircCNKSR2 Facilitates NSCLC Tumorigenesis and Warburg Effect via miRNA-138-5p/PLEK2 Axis [0.03%]
环状RNACNKSR2通过miRNA-138-5p/PLEK2轴促进NSCLC肿瘤发生和Warburg效应
Dongxiao Ding,Ke Shi,Junjie Ying et al.
Dongxiao Ding et al.
Non-small cell lung cancer (NSCLC) has a high global incidence and mortality rate. Although circRNAs have significant attention in tumor research, it's role in NSCLC is uncertain. QRT-PCR and Western blotting were utilized to quantify the e...
Epigenetic Signatures and Prognostic Biomarkers Analysis of Methylation-Driven Genes in Uterine Endometrial Carcinosarcoma [0.03%]
子宫内膜癌肉瘤中甲基化驱动基因的表观遗传标记和预后生物标志物分析
Na Zhang,Wangshu Li,Fang Wang et al.
Na Zhang et al.
Uterine corpus endometrial carcinoma (UCEC) is one of the most common gynecological malignancies, and understanding the molecular mechanisms underlying its development is essential for improving diagnosis and treatment. However, the role of...
Plumbagin Induces Apoptosis in Diffuse Large B-Cell Lymphoma by Modulating the ROS-PI3K-Akt-mTOR Signaling Pathway [0.03%]
黄芩素通过调节ROS-PI3K-Akt-mTOR信号通路诱导弥漫性大B细胞淋巴瘤发生凋亡
Jingfang Du,Tao Ye,Pian Li et al.
Jingfang Du et al.
This study aimed to investigate the potential effects and underlying mechanism of plumbagin (PL) on the proliferation and apoptosis of SU-DHL-4 cells, a type of diffuse large B-cell lymphoma (DLBCL), through in vitro and in vivo experiments...
Structure Analysis and Site-Directed Mutagenesis of the Glycosyltransferase UGT71B8 Leads to Increased Stability and Substrate Activity in Arabidopsis thaliana [0.03%]
UGT71B8的糖基转移酶结构分析和定点突变可提高阿拉伯芥中的稳定性和底物活性
Humara Naz Majeed,Sumera Shaheen,Sadaf Saleem et al.
Humara Naz Majeed et al.
The uridine diphosphate-glycosyltransferase (UGT) family catalyses the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (substrate), it serves as controlling reaction for bioactivity, storage and decrease ...