HECW1 Gene's Role in Gastric Cancer Prognosis and Its Suppressive Effect on Cell Progression after Knockdown [0.03%]
HECW1基因在胃癌预后中的作用及其敲低后的抑瘤作用机制研究
Jinchuan Wang,Baozhen Wang,Yichen Yin et al.
Jinchuan Wang et al.
Background: The HECT, C2, and WW domain-containing E3 ubiquitin protein ligase 1 (HECW1) gene is a member of the HECT family of E3 ubiquitin ligases. While HECW1 has been implicated in various cancers, its role in gastric...
Identification and Validation of T Cell-Related Hub Biomarkers for Early Diagnosis of Diabetic Kidney Disease Using Single-Cell and Bulk Dataset Analysis [0.03%]
利用单细胞和批量数据分析鉴定和验证T细胞相关枢纽生物标志物以实现糖尿病肾脏疾病的早期诊断
Zhenhua Wu,Meifang Ren,Miao Tan et al.
Zhenhua Wu et al.
Diabetic kidney disease (DKD) is the most common complication of diabetes and a leading cause of chronic kidney disease that frequently leads to end-stage renal disease (ESRD). The pathogenesis of DKD is complex and is not fully understood....
Clinical characteristics and gene analysis in 7 Chinese children with cystic fibrosis [0.03%]
中国7例囊性纤维化患儿的临床特征和基因分析
Chunyan Guo,Xing Chen,Fengqin Liu et al.
Chunyan Guo et al.
Background: Cystic fibrosis (CF) is common genetic disorder in Europe and North America but rarer in Asian populations. Objective: To e...
Discovery of Target Genes for Fibromyalgia through Bioinformatics Analysis [0.03%]
通过生物信息学分析发现纤维肌痛的目标基因
Mao Guo,Botao Zhang
Mao Guo
Fibromyalgia (FM) is a chronic condition marked by widespread pain, fatigue, and other debilitating symptoms, affecting 2-4% of the population, predominantly women. Diagnosing FM is challenging due to its complex symptoms and lack of specif...
Changes in the Levels of the Serum Markers Serum Amyloid A and Immunoglobulin M in Children with Mycoplasma pneumoniae Infection Complicated with Asthma and Their Clinical Significance [0.03%]
支原体肺炎合并哮喘患儿血清血管性血浆蛋白A和免疫球蛋白M水平变化及临床意义
Shanshan Xiao,Xuejing Hou
Shanshan Xiao
Asthma represents a chronic disorder with aberrant immunological and inflammatory responses. We analyzed the levels and clinical significance of serum markers serum amyloid A (SAA) and immunoglobulin M (IgM) in Mycoplasma pneumoniae (MP)-in...
Identification of Ferroptosis-Associated Genes in Primary Open-Angle Glaucoma through Bioinformatics Analysis [0.03%]
基于生物信息学分析的原发性开角型青光眼铁死亡相关基因的鉴定
Dongmei Hong
Dongmei Hong
This study aims to examine ferroptosis-associated genes in primary open-angle glaucoma (POAG) and offer new insights into the underlying disease mechanisms and potential therapeutic approaches. Differentially expressed genes (DEGs) between ...
NEK6 Accelerates Hepatocellular Carcinoma Progression and Glycolysis through Ubiquitination of TCP10L [0.03%]
NEK6通过TCP10L泛素化促进肝细胞癌进展和糖酵解
Ling Su,Dehong Zhao,Cheng Zhou et al.
Ling Su et al.
Never in mitosis a related kinases 6 (NEK6) is a serine/threonine kinase, and dysregulation of NEK6 is associated with malignant progression of human cancers. Nonetheless, the biological function and molecular mechanism of NEK6 in hepatocel...
Role of the Transcription Factor FoxO in Type 2 Diabetes and Its Complications [0.03%]
转录因子FoxO在二型糖尿病及其并发症中的作用
Jing Hui Shi,Yi Biao Shi,Si Tian Qiu et al.
Jing Hui Shi et al.
FoxO proteins represent a subfamily of the forkhead box family (Fox) superfamily of proteins. It is involved in cell proliferation, differentiation, oxidative stress, apoptosis as well as tumors and metabolic disorders by regulating cellula...
Cancer Network Macromolecules [0.03%]
癌症网络大分子
George L Eliceiri
George L Eliceiri
The members of the network (interactome) that controls cancer needs to be known. This network consists of proteins and non-coding, single-stranded RNAs, such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), a...
Specific Non-Coding RNAs Involve in and Regulate the Transcriptional Network during Keloid Formation [0.03%]
特定的非编码RNA参与并调控瘢痕疙瘩形成过程中的转录网络
Xun Zhang,Linlin Song,Yong Ma et al.
Xun Zhang et al.
Keloid formation is an undesirable outcome of wound healing and is detrimental to patients' physical and mental health, while the molecular regulators of its pathogenesis, especially non-coding RNAs (ncRNAs), are largely unknown. In this st...