Muhammad Imran Qadir,Bilal Ahmed,Sumaira Noreen
Muhammad Imran Qadir
Neuroblastoma is a malignant tumor of neuroblasts, immature nerve cells found in several areas of the body. It usually affects children under age of 5. As usual, the tumor has ability to grow rapidly and to expand vastly which ultimately le...
Analysis of Transgenic Cotton Plants Containing Universal Stress Protein (GaUSP-1, GaUSP-2) and Zinc Finger Transcriptional Factor (GaZnF) Genes under Drought Stress [0.03%]
干旱胁迫下通用应激蛋白(GaUSP-1，GaUSP-2)和锌指转录因子(GaZnF)基因转基因棉株分析
Muhammad Hamza Basit,Bushra Rasheed,Kausar Malik et al.
Muhammad Hamza Basit et al.
Water is the most limiting factor for plant growth and crop productivity. Drought stress adversely affects crop yield throughout the world. Up to 50% of crop yield in Pakistan is severely affected by the shortage of water. Cotton is an impo...
K-Homology Type Splicing Regulatory Protein: Mechanism of Action in Cancer and Immune Disorders [0.03%]
K-同源型拼接调控蛋白：其在癌症和免疫性疾病中的作用机制
Jonathan D Leavenworth,Nabiha Yusuf,Quamarul Hassan
Jonathan D Leavenworth
K homology-type splicing regulatory protein (KSRP) is emerging as a key player in cancer biology, and immunology. As a single-strand nucleic acid binding protein it functions in both transcriptional and post-transcriptional regulation, whil...
Multispectral Imaging of Metabolic Fluorophores: Comparing In Vivo and Fresh Ex Vivo Tissue [0.03%]
代谢荧光物质的多光谱成像：体内与新鲜离体组织的比较
Gary E Carver,Sarah A Locknar,Prachi N Ghule et al.
Gary E Carver et al.
The enhanced uptake of glucose by cancer cells via aerobic glycolysis occurs when the lactic acid pathway is favored over the citric acid cycle. The lactic acid cycle in cancer cells influences the cytosolic concentration of metabolic fluor...
The ceRNA Mechanism of lncRNA MEG3/miR-21-5p/SPRY2 in Cell Proliferation and Apoptosis in Bladder Cancer [0.03%]
长链非编码RNA MEG3通过ceRNA机制调控miR-21-5p/SPRY2轴影响膀胱癌细胞增殖及凋亡的功能研究
Yangchun Hong,Zhen Li,Yixin Su et al.
Yangchun Hong et al.
Bladder cancer (BC) is the second most common genitourinary malignancy. Long noncoding RNA (lncRNA) is implicated in BC progression. This study delved into the underlying mechanism of lncRNA MEG3 in BC. Bioinformatics analysis predicted the...
Comprehensive Characterization of HATs and HDACs in Human Cancers Reveals Their Role in Immune Checkpoint Blockade [0.03%]
组蛋白修饰酶在人类癌症中的全面特征分析揭示了它们在免疫检查点阻断中的作用
Rong Sun,Zike Chen,Xuanhao Qu et al.
Rong Sun et al.
Histone acetylation that controlled by two mutually antagonistic enzyme families, histone acetyl transferases (HATs) and histone deacetylases (HDACs), as one of major epigenetic mechanisms controls transcription and its abnormal regulation ...
miRNA-27b-3p/TPX2 Axis Regulates Clear Cell Renal Cell Carcinoma Cell Proliferation, Invasion and Migration [0.03%]
微RNA-27b-3p/TPX2轴调节透明细胞肾细胞癌增殖、侵袭和迁移
Nana Liu,Yicheng Jiang,Shiyuan Chen et al.
Nana Liu et al.
There is a wide variety of cancer cells that can be linked to the presence of TPX2. However, there is not a lot of evidence regarding its role in the development and maintenance of clear cell renal cell carcinoma (ccRCC). In our study, bioi...
Long Noncoding RNA lnc-TCEA1-3 Affects Osteoclastic Function by Regulating ATP6V1H [0.03%]
长非编码RNA lnc-TCEA1-3通过调节ATP6V1H影响破骨细胞功能
Yuzhuan Hou,Shaoqing Yang,Zanyan Zhao et al.
Yuzhuan Hou et al.
H subunit of V-ATPase (ATP6V1H) is specifically expressed in osteoclasts and its deficiency lead to osteoporosis. Our group previously found four intronic SNPs of ATP6V1H related to reduced bone mineral density, but the mechanisms was not c...
Oncolytic Virotherapy: An Advanced Microbial Approach for the Management of Cancer [0.03%]
溶瘤病毒疗法：一种先进的微生物抗癌方法
Muhammad Farhan Siddiq Rao,Bilal Ahmed,Muhammad Imran Qadir
Muhammad Farhan Siddiq Rao
Destruction of the tumor (cancerous) cells may be caused by live viruses, which have replicative ability and replicate selectively in tumor cells, known as oncolytic virotherapy. In comparison of conservative cancer therapy, tumor-selective...
TPP1 Inhibits DNA Damage Response and Chemosensitivity in Esophageal Cancer [0.03%]
TPP1抑制食管癌的DNA损伤反应和化学敏感性
Jilin Wen,Xiaowu Zhong,Chuanli Gao et al.
Jilin Wen et al.
TPP1, as one of the telomere-protective protein complex, functions to maintain telomere stability. In this study, we found that TPP1 was significantly upregulated in esophageal cancer (EC). We found that the proliferation and migration abil...