A R Brown
A R Brown
The spleen is a key lymphoid organ for generating B-lymphocyte (B cell)-mediated humoral immunity. This review examines the key features and functions of splenic B cells. Splenic B cell subsets, including virgin, memory, and CD5+ B cells, a...
Immunological functions and in vivo cell-cell interactions of T cells in the spleen [0.03%]
脾脏T细胞的免疫功能及其体内细胞间相互作用
A J Van den Eertwegh,W J Boersma,E Claassen
A J Van den Eertwegh
The spleen is an important lymphoid organ, involved in immune responses against all types of antigen that appear in the circulation. Its complex anatomical organization, with distinct compartments containing specialized cell types, provides...
Observations, legends, and conjectures concerning restricted T-cell receptor usage and autoimmune disease [0.03%]
有关T细胞受体限制性使用及自身免疫病的观察、传说和假说
T Esch,L Clark,X M Zhang et al.
T Esch et al.
It has become clear over the past few years that a variety of experimental autoimmune conditions are mediated by T cells bearing a highly restricted subset of antigen receptors. This restricted TcR usage raises important questions concernin...
J Choppin,J G Guillet,J P Lévy
J Choppin
To identify HIV peptides containing HLA class I binding regions, different studies have been performed. These include the detection of interactions between HIV peptides and purified HLA molecules in solid-phase assays, the measurement of HL...
T-cell receptors: germline polymorphism and patterns of usage in demyelinating diseases [0.03%]
T细胞受体：基因型多态性和在脱髓鞘病中的使用模式
K Usuku,N Joshi,S L Hauser
K Usuku
The genomic organization of the T-cell receptor (TCR) gene complexes accounts for many central aspects of T-cell immunobiology, including specificity and diversity. Recent data indicate that polymorphism of TCR genes is present within a spe...
Structural analysis of class II major histocompatibility complex proteins [0.03%]
Ⅱ类主要组织相容性复合体蛋白质的结构分析
J C Gorga
J C Gorga
Numerous studies have contributed much data that, taken together, provide considerable insight into the structural features of class II molecules. The putative peptide-binding region has been modeled from the crystal structure of the class ...
D Kabelitz
D Kabelitz
gamma/delta+ T-cells are a recently identified subpopulation of T-lymphocytes expressing an "alternative" T-cell receptor (TCR) molecule consisting of disulfate-linked or nonlinked gamma and delta chains. Despite a limited number of V gamma...
J Plachy,J R Pink,K Hála
J Plachy
The major histocompatibility complex (MHC) of chicken is the B complex, originally described as a blood group system. Its three classes of cell membrane antigens have been clearly defined by serological, histogenetic, biochemical, and molec...