Current status of the development of an AIDS vaccine [0.03%]
艾滋病疫苗的研究进展及存在问题分析综述论文摘要数据库统计词典词族簇集群原型 lstm transformer BERT口罩新冠疫情新冠病毒肺炎呼吸道传染病呼吸道疫情呼吸道病毒呼吸道防控
L A Lasky
L A Lasky
It is commonly agreed that the development of a vaccine that would prove effective against infection by the Human Immunodeficiency Virus, HIV, would be an important measure toward eliminating the Acquired Immunodeficiency Syndrome, AIDS. Th...
Mechanisms that regulate the production and effects of tumor necrosis factor-alpha [0.03%]
调节肿瘤坏死因子α产生的机制及其效应
S L Kunkel,D G Remick,R M Strieter et al.
S L Kunkel et al.
Macrophage-derived tumor necrosis factor (TNF) is increasingly being recognized as an important monokine possessing multifunctional activities. Current evidence has demonstrated that TNF can induce a number of pleomorphic effects in both ph...
A J Demetris,B H Markus
A J Demetris
Liver transplantation has become an accepted therapeutic modality for many patients with end-stage liver diseases. Compared to other solid organ allografts, the immunopathological mechanisms involved in the original disease, rejection react...
T Sminia,G J van der Brugge-Gamelkoorn,S H Jeurissen
T Sminia
This article deals with the ontogeny, morphology, and function of bronchus-associated lymphoid tissue (BALT). The surface epithelium of the respiratory tract, including the lymphoepithelium of BALT, is described, with emphasis on infiltrate...
N A Parfrey,G J Prudhomme,E Colle et al.
N A Parfrey et al.
The spontaneous development of diabetes in the Bio-Breeding (BB) rat is an excellent model of human insulin-dependent diabetes mellitus (IDDM). Disease expression is dependent on several genetically determined abnormalities, including speci...
M Trucco,J S Dorman
M Trucco
Diabetes mellitus is the second most prevalent chronic disease in children in the U.S. It is associated with severe manifestations which include blindness and circulation deficiencies as well as markedly increased risk of death. The etiolog...
M G Rosenblum,N J Donato
M G Rosenblum
Homeostasis at the cellular level appears to be a complex state of equilibrium derived, in part, from multiple interactions among lymphokines, cytokines, growth factors, and hormones. Tumor necrosis factor (TNF-alpha) secreted by mitogen-st...
C A Dinarello,N Savage
C A Dinarello
Interleukin-1 (IL-1) is a polypeptide that is produced during infection, injury, or immunologic challenge. There are two molecular forms, IL-1-beta and IL-1-alpha, and despite only a 26% amino acid homology, both forms induce a wide variety...
C A Gritzmacher
C A Gritzmacher
Ig heavy chain class switching results from recombination that specifically joins together tandemly repeated sequences called S-regions. S-regions are located 5' of every CH gene except C delta. Recombination between S mu and a downstream S...
Monoclonal antibodies to human major histocompatibility complex class II antigens [0.03%]
人类主要组织相容性复合物第二类抗原的单克隆抗体
S F Radka
S F Radka
The production and characterization of monoclonal antibodies to major histocompatibility complex (MHC) class II molecules have contributed significantly to delineating the number and structure of gene products of the D region of HLA. The "f...