P Cresswell,J S Blum,D N Kelner et al.
P Cresswell et al.
The class II major histocompatibility antigens at the cell surface exist as heterodimers of alpha and beta subunits. During biosynthesis, these subunits are associated with a third chain, the invariant (I) or I chain. Association with the I...
Cardiac transplantation: immune mechanisms and alloantigens involved in graft rejection [0.03%]
心脏移植：与移植物排斥反应相关的免疫机制及抗原
D V Cramer
D V Cramer
Recent advances in surgical and chemotherapeutic approaches to cardiac transplantation have resulted in substantial improvements in patient survival. Rejection of the cardiac allograft by the recipient's immune system and complications asso...
J Klein,F Figueroa
J Klein
The major histocompatibility complex is a group of closely linked loci that code for molecules used by T-lymphocytes as context for the recognition of antigens. The loci fall into two classes: I, coding for molecules used as context by cyto...
Placental immunoregulation [0.03%]
胎盘免疫调节作用
R D Hunziker,T G Wegmann
R D Hunziker
Mammalian gestation is complex and varies widely among species, but the embryonic contribution to the maternal-fetal interface, the trophoblast, remains constant. Alloantigen and stage/tissue specific antigens are present on the trophoblast...
G A Bishop,L W Arnold,G Haughton
G A Bishop
The topics covered in this review include: the origin and availability of murine B cell lymphomas bearing immunoglobulins of known antigen reactivity; their etiology and the role of antigen in lymphomagenesis; the extent to which such tumor...
R B Corley,C M Dexter,M Ovnic
R B Corley
T lymphocytes comprise a major class of lymphocytes and are themselves functionally heterogeneous. Some T lymphocyte functions are mediated by soluble products called lymphokines. Different lymphokines promote the activation, growth and dif...
Factors and events in the activation, proliferation, and differentiation of B cells [0.03%]
B细胞活化、增殖和分化的影响因素及事件
W O Weigle
W O Weigle
The cellular and biochemical pathways of B-cell activation and the role of antigen presentation by B cells are reviewed. It appears that B cells may be activated by two cellular pathways, one of which is MHC restricted, involving cognate re...
Regulation of H-2 class I gene expression in virally transformed and infected cells [0.03%]
病毒感染和转化的细胞中H-2类I基因表达的调控
G D Brown,Y Choi,C Pampeno et al.
G D Brown et al.
Early studies of the resistance and susceptibility of mouse strains to radiation-induced leukemia virus have demonstrated the important role of altered histocompatibility (H-2) antigen expression in the effectiveness of the immune response ...
Autoantibodies to DNA [0.03%]
抗DNA自身抗体
C Mackworth-Young,R S Schwartz
C Mackworth-Young
Naturally occurring antibodies directed against the principal component of the gene are conceptually remarkable as well as of great interest to both basic and applied immunologists. In this article, some of the important literature concerni...
H S Warren,L A Chedid
H S Warren
Since the landmark experiments of Ramon 60 years ago, attempts have been made to augment the humoral and cellular responses to administered antigens in order to develop more potent and less toxic vaccines. The need for an acceptable adjuvan...