Surface markers, antigens, and receptors on murine T and B cells: part 2 [0.03%]
小鼠T和B细胞表面标志物、抗原和受体(第二部分)
A Ahmed,A H Smith
A Ahmed
One of the greatest challenges that has confronted the cellular biologist for the past decade has been the understanding of the basic mechanisms that underlie the interaction of antigen with the cell surface and the subsequent cell-to-cell ...
C J Krco,C S David
C J Krco
The mouse has served as an invaluable model for investigations of immune response (Ir) genes. Of most importance has been major histocompatibility complex (MHC) linked Ir genes. The MHC genes have been demonstrated to be the prime factor in...
R M Welsh
R M Welsh
Natural killer cells are cytotoxic lymphocytes found in all examined vertebrates and implicated as mediators of tumor surveillance in experimental animal models. Normally cytotoxic for a selective group of tumor target cells, NK cells can b...
Discovery and implications of the immunogenicity of free small synthetic peptides: powerful tools for manipulating the immune system and for production of antibodies and T cells of preselected submolecular specificities [0.03%]
自由状态下的小合成肽具有免疫原性及其意义:一种强有力的工具,可操纵免疫系统并产生预先选定的亚分子特异性的抗体和T细胞
M Z Atassi,C R Young
M Z Atassi
Recent studies from this laboratory have found, contrary to a long-held belief, that synthetic peptides of a protein, as small as six residues, when immunized in their free form (i.e., without coupling to any carrier), elicit the formation ...
Human monocytes and macrophages: establishment and analysis of cloned populations and functional cell lines [0.03%]
人单核细胞和巨噬细胞的建系及功能分析
A J Treves
A J Treves
Human monocytes and macrophages are heterogeneous cell populations, with numerous functions and activities. In the present work we review some new in vitro studies which made possible the development and research of cloned populations of ma...
C M Baum,J M Davie,J P McKearn
C M Baum
The review will examine B-cell differentiation with an emphasis on B-cell subpopulations. We will begin with an analysis of current evidence concerning B-cell ontogeny. The development of the B-cell repertoire will be traced from stem cell ...
I H Al-Abdullah,J Greally
I H Al-Abdullah
C1-inhibitor (C1-INH) is an alpha-2-neuraminoglycoprotein with a molecular weight of 105,000 daltons. It has a broad spectrum control of the many blood cascades including the complement system. Inherited deficiency of this molecule has been...
R W Chesnut,H M Grey
R W Chesnut
In this review we will examine the characteristics of the various cell types which have been shown to present antigens to helper and proliferating T cells and explore what is known about the requirements for antigen presentation by these ce...
Immunity and pregnancy [0.03%]
免疫系统与妊娠
T J Gill rd
T J Gill rd
The existence of the maternal immune response to various paternally derived antigens on the fetus and placenta is apparently paradoxical, since the immune response is generally associated with host defense. In this context, the immune respo...
Histamine modulation of lymphocyte biology: membrane receptors, signal transduction, and functions [0.03%]
组胺对淋巴细胞生物学的调节:膜受体、信号转导和功能
D J Beer,R E Rocklin
D J Beer
Until recently, histamine has been considered only in the context of its being the major mediator of immediate-type hypersensitivity responses. However, subsequent investigations have demonstrated an additional role for histamine as a regul...