Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro [0.03%]
自然杀伤细胞在口腔肿瘤根除和分化中的作用：一种基于细胞的免疫疗法，在体内和体外的作用
Kawaljit Kaur,Anahid Jewett
Kawaljit Kaur
Despite advancements in the field of cancer therapeutics, the five-year survival rate remains low in oral cancer patients. Therefore, the effective therapeutics are needed against oral cancer. Also, several studies including ours, have show...
Current and Future States of Natural Killer Cell-Based Immunotherapy in Hepatocellular Carcinoma [0.03%]
肝细胞癌的自然杀伤细胞免疫疗法的现状与未来状态
Tu Nguyen,Po-Chun Chen,Janet Pham et al.
Tu Nguyen et al.
Natural killer (NK) cells are innate lymphoid cells that exhibit high levels of cytotoxicity against NK-specific targets. NK cells also produce various cytokines, and interact with T cells, B cells, and dendritic cells to effectively serve ...
Phillygenin Alleviates Arthritis through the Inhibition of the NLRP3 Inflammasome and Ferroptosis by AMPK [0.03%]
Phillygenin通过AMPK介导的抑制NLRP3炎性小体和铁死亡来缓解关节炎
Jianghui Wang,Shufang Ni,Kai Zheng et al.
Jianghui Wang et al.
We investigated the potential arthritis-inducing effects of Phillygenin and its underlying mechanisms. RAW264.7 cells were stimulated with lipopolysaccharide to induce inflammation. Phillygenin was found to reduce arthritis score, histopath...
The Protective Effect and Mechanism of Mild Hypothermia on Lung Injury after Cardiopulmonary Resuscitation in Pigs [0.03%]
轻度低温对猪心肺复苏后肺损伤的保护效应及机制研究
Jinlin Ren,Fangfang Zhu,Dongdong Sang et al.
Jinlin Ren et al.
To explore the protective effect and mechanism of mild hypothermia on lung tissue damage after cardiopulmonary resuscitation in pigs. In this experiment, we electrically stimulated 16 pigs (30 ± 2 kg) for 10 min to cause ventricular fibril...
Efficacy and Nuances of Precision Molecular Engineering for Hodgkin's Disease to a Gene Therapeutic Approach [0.03%]
霍奇金病的精准分子工程疗效及基因治疗方法的细微差别
Muhammad Imran Qadir,Bilal Ahmed,Nadir Hussain
Muhammad Imran Qadir
Gene therapy is a particularly useful treatment for nervous system genetic diseases, including those induced especially by infectious organisms and antigens, and is being utilized to treat Hodgkin's disease (HD). Due to the possible clonal ...
Exploring the Mechanism of Zilongjin in Treating Lung Adenocarcinoma Based on Network Pharmacology Combined with Experimental Verification [0.03%]
基于网络药理学结合实验验证探究支龙金治疗肺腺癌的机制
Kang Zhang,Xiaoqun Chen
Kang Zhang
Zilongjin (ZLJ) is a common traditional Chinese medicine for lung adenocarcinoma (LUAD) treatment. However, its mechanisms of action remain to be elucidated. Network pharmacology was used to explore the underlying mechanisms of ZLJ on LUAD ...
Exploration of Diagnostic Markers Associated with Inflammation in Chronic Kidney Disease Based on WGCNA and Machine Learning [0.03%]
基于WGCNA和机器学习的慢性肾脏病相关炎症诊断标志物的研究探索
Qianjia Wu,Yang Yang,Chongze Lin
Qianjia Wu
Chronic kidney disease (CKD) is a common disorder related to inflammatory pathways; its effective management remains limited. This study aimed to use bioinformatics analysis to find diagnostic markers that might be therapeutic targets for C...
Gastric Cancer Immune Subtypes and Prognostic Modeling: Insights from Aging-Related Gene Analysis [0.03%]
胃癌免疫分型及预后模型构建：基于衰老相关基因分析的启示
Jian Shen,Minzhe Li
Jian Shen
Gastric cancer (GC) is highly heterogeneous and influenced by aging-related factors. This study aimed to improve individualized prognostic assessment of GC by identifying aging-related genes and subtypes. Immune scores of GC samples from GE...
Identification of Key Ubiquitination-Related Genes and Their Association with Immune Infiltration in Osteoarthritis Based on the mRNA-miRNA Network [0.03%]
基于mRNA-miRNA网络的骨关节炎关键泛素化相关基因鉴定及其与免疫浸润的关系分析
Dalu Yuan,Hailiang Shen,Lina Bai et al.
Dalu Yuan et al.
Osteoarthritis (OA) is a prevalent degenerative joint disease that is closely associated with functions of ubiquitination and immune cells, yet the mechanism remains ambiguous. This study aimed to find core ubiquitination-related genes and ...
Diagnostic and Prognostic Value of Peripheral Neutrophil CD64 Index in Elderly Patients with Community-Acquired Pneumonia [0.03%]
老年社区获得性肺炎患者外周中性粒细胞CD64指数的诊断及预后价值分析
Yan Li,Jing Zhang,Suhang Wang et al.
Yan Li et al.
Community-acquired pneumonia (CAP) is a leading cause of hospitalization and mortality in the elderly. The peripheral blood neutrophil CD64 (nCD64) index is increasingly recognized for its association with poor pneumonia prognosis. A compre...