EPR and electrochemical quantification of oxygen using newly synthesized para-silylated triarylmethyl radicals [0.03%]
新型对硅基三芳甲基自由基的EPR和电化学氧测定法研究
A Boutier-Pischon,F Auger,J-M Noël et al.
A Boutier-Pischon et al.
Novel silylated triarylmethyl (TAM) radicals based on TAM core CT-03 and their electron paramagnetic resonance (EPR) spectra are evaluated as a function of oxygen concentration. Combination of peak-to-peak linewidth of the EPR signal and el...
Characterization of recombinant human gastrointestinal glutathione peroxidase mutant produced in Escherichia coli [0.03%]
重组人胃肠道谷胱甘肽过氧化物酶突变体的性质分析
X Guo,J Song,T Guan et al.
X Guo et al.
Gastrointestinal glutathione peroxidase (GI-GPx, GPx2) is a selenium-dependent enzyme and regarded as the first line of defense against oxidative stress caused by ingested pro-oxidants or gut microbes. As the essential part of the catalytic...
Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide [0.03%]
过氧化氢诱导的胃损害及自噬抑制的硫氰酸吡咯烷.restore gastric damages和suppressive autophagy翻译时调整语序为“由过氧化氢引起的胃损害及其自噬抑制”更加符合中文表达习惯。
J L Duan,J Yin,W K Ren et al.
J L Duan et al.
It is well known that gastric barrier is very important for protecting host from various insults. Simultaneously, autophagy serving as a prominent cytoprotective and survival pathway under oxidative stress conditions is being increasingly r...
Reduction of prohibitin expression contributes to left ventricular hypertrophy via enhancement of mitochondrial reactive oxygen species formation in spontaneous hypertensive rats [0.03%]
prohibin表达下调通过增强 SHR心肌线粒体ROS生成参与 LVH 发生
H Zheng,G M Lu
H Zheng
Left ventricular hypertrophy (LVH) in hypertension is characterized by thickening of myocardium and decrease in heart chamber volume in response to mechanical or pathological stress, but the underlying molecular mechanisms remain to be defi...
Arterial tissue and plasma concentration of enzymatic-driven oxysterols are associated with severe peripheral atherosclerotic disease and systemic inflammatory activity [0.03%]
动脉组织和血浆中酶源性氧化固醇浓度与下肢严重外周动脉疾病及全身炎症活动之间的关系研究
V W M Virginio,V S Nunes,F A Moura et al.
V W M Virginio et al.
Introduction: Cholesterol undergoes oxidation via both enzymatic stress- and free radical-mediated mechanisms, generating a wide range of oxysterols. In contrast to oxidative stress-driven metabolites, enzymatic stress-de...
Late-intervention study with ebselen in an experimental model of type 1 diabetic nephropathy [0.03%]
硫辛在1型糖尿病肾病实验模型中的晚期干预研究
S M Tan,A Sharma,N Stefanovic et al.
S M Tan et al.
Background and aim: Previous studies have shown that preventive treatment with the antioxidant, ebselen, in experimental models of type 1 diabetic nephropathy resulted in an attenuation of structural and functional damage...
Ankyrin is the major oxidised protein in erythrocyte membranes from end-stage renal disease patients on chronic haemodialysis and oxidation is decreased by dialysis and vitamin C supplementation [0.03%]
ANKRY是终末期肾病维持性血液透析患者红细胞膜上主要的氧化蛋白，透析和维生素C可降低其氧化水平
T Ruskovska,S J Bennett,C R Brown et al.
T Ruskovska et al.
Chronically haemodialysed end-stage renal disease patients are at high risk of morbidity arising from complications of dialysis, the underlying pathology that has led to renal disease and the complex pathology of chronic kidney disease. Ana...
Oxidation of glycosaminoglycans by free radicals and reactive oxidative species: A review of investigative methods [0.03%]
糖胺聚糖的自由基和反应性氧化物质氧化：研究方法综述
B J Parsons
B J Parsons
Glycosaminoglycans, in particular hyaluronan (HA), and proteoglycans are components of the extracellular matrix (ECM). The ECM plays a key role in the regulation of cellular behaviour and alterations to it can modulate both the development ...
Lycopene protects pancreatic acinar cells against severe acute pancreatitis by abating the oxidative stress through JNK pathway [0.03%]
番茄红素通过JNK途径减轻氧化应激来保护急性重症胰腺炎患者的胰腺外分泌细胞
J C Lv,G Wang,S H Pan et al.
J C Lv et al.
This study investigated the anti-oxidative and anti-inflammatory effects of lycopene on severe acute pancreatitis (SAP) in both in vivo and in vitro models. Utilizing a rat model, we found that lycopene administration protected against SAP,...
The neuroprotective effects of β-hydroxybutyrate on Aβ-injected rat hippocampus in vivo and in Aβ-treated PC-12 cells in vitro [0.03%]
β-羟基丁酸对Aβ海马注射及PC-12细胞Aβ处理的神经保护作用研究
G Xie,W Tian,T Wei et al.
G Xie et al.
Alzheimer's disease is a neurodegenerative disorder associated with the deposition of the peptide amyloid-beta (Aβ) in senile plaques and cerebral vasculature. The neurotoxic mechanisms of this condition have been linked to oxidative-stres...