Potential targetability of multi-walled carbon nanotube loaded with silver nanoparticles photosynthesized from Ocimum tenuiflorum (tulsi extract) in fertility diagnosis [0.03%]
用圣 Basilace 提取物光合成的银纳米颗粒负载型多壁碳纳米管在生育诊断中的潜在靶向性研究
Pradeep K Jha,Rakhi K Jha,Dilip Rout et al.
Pradeep K Jha et al.
Nanocarrier mediated targeted delivery and biosensing in reproductive health care is a major exploratory domain. This work demonstrates the loading of silver nanoparticle (AgNP) inside the multiwalled carbon nanotube (MWCNT) and their targe...
Curcumin inhibits urothelial tumor development by suppressing IGF2 and IGF2-mediated PI3K/AKT/mTOR signaling pathway [0.03%]
姜黄素通过抑制IGF2和IGF2介导的PI3K / AKT / mTOR信号传导途径抑制尿路上皮肿瘤的发展
Binqiang Tian,Yingmei Zhao,Tao Liang et al.
Binqiang Tian et al.
We have previously reported that curcumin inhibits urothelial tumor development in a rat bladder carcinogenesis model. In this study, we report that curcumin inhibits urothelial tumor development by suppressing IGF2 and IGF2-mediated PI3K/A...
The efficacy of WGA modified daunorubicin anti-resistant liposomes in treatment of drug-resistant MCF-7 breast cancer [0.03%]
WGA修饰的柔红霉素抗药脂质体对耐药MCF-7乳腺癌的疗效研究
Shuang Liu,Xiao-Li Song,Yan-Hong Wang et al.
Shuang Liu et al.
Background: Breast cancer is the most common malignancy and remains a leading cause of cancer-related deaths in female. Chemotherapy failure of breast cancer is mainly associated with multidrug resistance of cancer cells....
Polymer-based drug delivery: the quest for local targeting of inflamed intestinal mucosa [0.03%]
基于聚合物的药物输送：靶向炎症肠粘膜的探索
M Junaid Dar,Hussain Ali,Amjad Khan et al.
M Junaid Dar et al.
Colon-specific drug delivery has found important applications in the wide array of diseases affecting the lower intestinal tract. Recent developments and advancements in the polymer-based colonic delivery ensure targeted therapeutics with r...
α-Tocopherol as functional excipient for resveratrol and coenzyme Q10-loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer [0.03%]
作为白藜芦醇和辅酶Q10负载型SNEDDS功能辅料的α-生育酚改善生物利用度及乳腺癌预防作用的研究
Sanyog Jain,Tanya Garg,Varun Kushwah et al.
Sanyog Jain et al.
The present study evaluates the prophylactic efficacy of α-tocopherol (α-TOH), resveratrol (RES), and coenzyme Q10 (CoQ10) co-loaded self-nanoemulsifying drug delivery system (α-TOH-RES-CoQ10 SNEDDS) in 7,12-Dimethylbenz[a]anthracene (DM...
Comparative Study
Journal of drug targeting. 2017 Jul;25(6):554-565. DOI:10.1080/1061186X.2017.1298603 2017
Amrita Banerjee,Jessica Wong,Rohan Gogoi et al.
Amrita Banerjee et al.
Diabetes mellitus has become a major public health issue that has almost reached epidemic proportions worldwide. Injectable insulin has been typically utilized for the management of this chronic disease. However, lack of patient compliance ...
Uday Krishna Baruah,Kuppusamy Gowthamarajan,Ravisankar Vanka et al.
Uday Krishna Baruah et al.
We reside in an era of technological innovation and advancement despite which infectious diseases like malaria remain to be one of the greatest threats to the humans. Mortality rate caused by malaria disease is a huge concern in the twenty-...
Enhanced blood-brain barrier transport of vinpocetine by oral delivery of mixed micelles in combination with a message guider [0.03%]
一种口服混合微胶粒传递系统结合信息引导技术增强贯叶金丝桃向脑内转运的研究
Jiaojiao Ding,Yujiao Sun,Jinfeng Li et al.
Jiaojiao Ding et al.
The blood-brain barrier represents an insurmountable obstacle for the therapy of central nervous system related diseases. Polymeric micelles have many desirable properties for brain targeting by oral delivery, but the stability and targetin...
Novel nanoparticulate systems for lung cancer therapy: an updated review [0.03%]
用于肺癌治疗的新颖型纳米粒子系统：综述更新
Asadullah Madni,Amna Batool,Sobia Noreen et al.
Asadullah Madni et al.
Lung cancer is the leading cause of cancer-related deaths in the world. Conventional therapy for lung cancer is associated with lack of specificity and access to the normal cells resulting in cytotoxicity, reduced cellular uptake, drug resi...
Recent developments in trans-sialidase inhibitors of Trypanosoma cruzi [0.03%]
近期克氏锥虫trans-唾液酸酶抑制剂的研究进展
Muhammad Kashif,Antonio Moreno-Herrera,Edgar E Lara-Ramirez et al.
Muhammad Kashif et al.
Chagas is a lethal chronic disease that currently affects 8-10 million people worldwide, primarily in South and Central America. Trypanosoma cruzi trans-sialidase is an enzyme that is of vital importance for the survival of the parasite due...