Sacituzumab Govitecan in HER2-Negative Breast Cancer: Redefining Treatment Paradigms [0.03%]
治疗HER2阴性乳腺癌： Sacituzumab Govitecan重新定义了治疗模式
Avinash Khadela,Kashvy R Morakhia,Nishra H Shah et al.
Avinash Khadela et al.
Human epidermal growth factor 2-negative breast cancer (HER2-BC) is characterized by the lack of HER2 amplification and encompasses triple-negative breast cancer and hormone receptor-positive HER2-negative breast cancer. Triple-negative bre...
Emerging Polymeric Mucoadhesive Nanocarriers: A Promising Option for Intravaginal HIV Preexposure Prophylaxis [0.03%]
用于阴道给药的聚合物粘膜粘附纳米载体有望成为暴露前预防艾滋病感染的新选择
Avichal Kumar,Dhruti Avlani,S Narasimha Murthy et al.
Avichal Kumar et al.
The emergence of novel long-acting and antiretroviral (ARV) drug delivery systems has reshaped the landscape of HIV pre-exposure prophylaxis (PrEP). Intravaginal delivery platforms are increasingly recognized for their ability to deliver AR...
Correction [0.03%]
改正
Published Erratum
Journal of drug targeting. 2025 Jun 23:1. DOI:10.1080/1061186X.2025.2522505 2025
Exogenous GABA as a natural epigenetic modifier for managing glycemic memory and diabetic nephropathy by modifying the epigenetic axis [0.03%]
外源GABA通过调节表观遗传轴用于管理糖基记忆和糖尿病肾病的自然表观遗传修饰剂
Kriti Kushwaha,Debojyoti Mandal,Sourbh Suren Garg et al.
Kriti Kushwaha et al.
Background: Glycemic memory plays a crucial role in the progression of diabetic nephropathy (DN), even after glycemic control is achieved. This study aimed to evaluate γ-aminobutyric acid (GABA), a natural compound ident...
Protective Efficacy of pDNA Vaccine Candidate Against SARS-CoV-2 in Syrian Golden Hamsters [0.03%]
候选pDNA疫苗对叙利亚金仓鼠预防新冠肺炎的效力研究
Iman Almansour Alzamil,Serguei Golovan,Jennifer Pickens et al.
Iman Almansour Alzamil et al.
Seasonal SARS-CoV-2 vaccination is known as an efficient way to control the COVID-19 pandemic. However, the currently approved mRNA and protein vaccines are thermally unstable and require further encapsulation and ultra-cold chain transport...
Emerging Role of Gene Therapy in Immune Modulation and Beta-Cell Preservation in Type 1 Diabetes [0.03%]
基因治疗在免疫调节和1型糖尿病胰岛β细胞保存中的新兴作用
Rahul Mittal,Vedaant Mutha,Eavin A Valerio et al.
Rahul Mittal et al.
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β cells, which leads to chronic hyperglycemia and lifelong insulin dependence. Despite advances in diabetes care, achieving optimal glucos...
Correction [0.03%]
改正通知
Published Erratum
Journal of drug targeting. 2025 Jun 19:1. DOI:10.1080/1061186X.2025.2522497 2025
A Novel Mucoadhesive Phytic Acid Grafted Chitosan Nanocarrier Encapsulated with Cisplatin for Site-Specific Cervical Cancer Therapy: In-Vitro and In-Vivo Assessments [0.03%]
一种新型粘附植酸接枝壳聚糖纳米载体，用于位点特异性宫颈癌治疗的顺铂包载：体外及体内评估
Ivy Saha,Jitu Halder,Tushar Kanti Rajwar et al.
Ivy Saha et al.
A mucoadhesive vaginal drug delivery system offers a promising strategy to mitigate chemotherapy-associated systemic toxicity in cervical cancer. Metalloenzymes like superoxide dismutase 2 (SOD2) and catalase are responsible for maintaining...
The hybrid nano-platform based on ZIF-8 realizes the synergistic therapy of tumor chemo-immunotherapy [0.03%]
基于ZIF-8的杂化纳米平台实现肿瘤化疗免疫治疗协同效应
Haolong Qi,Yingjie Geng,Yuan Li et al.
Haolong Qi et al.
Immunotherapy has attracted widespread attention as a new tumor treatment method. Because of the low response rate, immunotherapy is only effective for some patients. With the continuous exploration of tumor immunity, the concept of immunog...
Advances in targeted therapy for triple-negative breast cancer: a review of key antigens and recent advances [0.03%]
三阴性乳腺癌靶向治疗进展：关键抗原与近期研究动态的综述
Bahman Akbari,Md Mehedi Hasan,Shahidul M Islam
Bahman Akbari
The most aggressive subtype of breast cancer is triple-negative breast cancer (TNBC), which affects about 10-15% of all breast cancer cases. TNBC is associated with a poor prognosis and drug resistance due to the lack of oestrogen, progeste...