Production of active human FGF21 using tobacco mosaic virus-based transient expression system [0.03%]
基于烟草花叶病毒的瞬时表达系统生产活性人FGF21蛋白质
Jieying Fan,Yunpeng Wang,Shuang Huang et al.
Jieying Fan et al.
Fibroblast growth factor (FGF) family has a wide range of metabolic processes. FGF21 exerts critical physiological functions in clinical application. This study aimed to explore a convenient and highly efficient approach for rhFGF21 express...
Myokine-mediated exercise effects: the role of myokine meteorin-like hormone (Metrnl) [0.03%]
肌细胞因子介导的运动作用：肌细胞因子meteorin-like激素(Metrnl)的作用
Hamid Alizadeh
Hamid Alizadeh
Meterorin-like hormone (Metrnl), as a novel secreted factor, has been shown to be involved in physiological and pathophysiological processes. The behaviour of Metrnl in metabolic conditions like type 2 diabetes is conflicting. Metrnl-mediat...
Vasomotor tone-associated factors and pregnancy outcomes of women who undergo in vitro fertilization [0.03%]
与血管张力相关的因素和体外受精妇女的妊娠结局
Yonglian Lan,Xiaokui Yang,Yu Liang et al.
Yonglian Lan et al.
Vasomotor tone-associated factors play important roles in normal pregnancy, but their roles in the pregnancy outcome of women who undergo in vitro fertilization and embryo transfer (IVF-ET) remain unclear. A total of 82 infertile women who ...
Seyed Kazem Shakouri,Sanam Dolati,Jessica Santhakumar et al.
Seyed Kazem Shakouri et al.
Autologous conditioned serum (ACS) is a blood-derived product that is prepared by the incubation of whole blood with medical-grade glass beads, resulting in serum enrichment in interleukin-1 receptor antagonist (IL-1Ra), anti-inflammatory c...
Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114 [0.03%]
纤维细胞生长因子1衍生物TTHX1001和TTHX1114对兔角膜内皮细胞的再生反应研究
Jessica Weant,David D Eveleth,Amuthakannan Subramaniam et al.
Jessica Weant et al.
Utilising rabbit corneal endothelial cells (CEC) in three different paradigms, two human FGF1 derivatives (TTHX1001 and TTHX1114), engineered to exhibit greater stability, were tested as proliferative agents. Primary CECs and mouse NIH 3T3 ...
Andrea Marlene García Muro,Azaria García Ruvalcaba,Lourdes Del Carmen Rizo de la Torre et al.
Andrea Marlene García Muro et al.
The BMP6 protein (Bone Morphogenetic Protein 6) is part of the superfamily of transforming growth factor-beta (TGF-β) ligands, participates in iron homeostasis, inhibits invasion by increasing adhesions and cell-cell type interactions and ...
miRNA-26-5p inhibits cyclosporine A-induced overgrowth of gingival fibroblasts by regulating PTEN/PI3K/AKT pathway [0.03%]
微小核糖核酸-26-5p通过调节PTEN/PI3K/AKT信号通路抑制环孢素A诱导的牙龈成纤维细胞过度增殖
Qiyong Hu,Nadan Guo,Yuting Zhao et al.
Qiyong Hu et al.
We evaluated the effect of cyclosporine A (CsA) administration on the level of miR-26-5p in rat gingival tissues and human gingival fibroblasts (HGFs) by qRT-PCR assay. Further, we conducted Western blotting and immunohistochemical analysis...
Third-degree burn mouse treatment using recombinant human fibroblast growth factor 2 [0.03%]
人表皮生长因子治疗3度烧伤小鼠实验研究
Thu-Minh Tran-Nguyen,Khanh-Thien Le,Le-Giang Thi Nguyen et al.
Thu-Minh Tran-Nguyen et al.
Fibroblast growth factor 2 (FGF-2) is a multifunctional protein that has major roles in wound healing, tissue repair, and regeneration. This therapeutic protein is widely used for burn treatment because it can stimulate cell proliferation a...
Insulin and IGF-2 support rat corneal endothelial cell growth and wound repair in the organ cultured tissue [0.03%]
胰岛素和IGF-2支持组织培养中的再生性大鼠角膜内皮细胞生长和伤口愈合
Sheldon R Gordon,Darryl R Reaume,Thomas R Perkins
Sheldon R Gordon
The ability of insulin and IGF-2 to support wound repair in the organ-cultured rat corneal endothelium was investigated. Corneas given a circular transcorneal freeze injury, were explanted into organ cultures containing either insulin or IG...
Effect of fasting on body composition and proteolysis gene expression in skeletal muscles and liver of BEH+/+ and BEL mice [0.03%]
禁食对BEH+/+和BEL小鼠骨骼肌和肝脏身体组成及蛋白分解代谢基因表达的影响
Edgaras Lapinskas,Raulas Krusnauskas,Agne Cekanauskaite et al.
Edgaras Lapinskas et al.
Fasting improves health, but can cause muscle weakness. We assessed body composition in 21-week old males of Berlin high (BEH+/+) and Berlin low (BEL) strains after two bouts of 48-h or 40-h of fasting with 5-day refeeding in between, respe...