OP-1 injection increases VEGF expression but not angiogenesis in a rabbit model of distraction osteogenesis [0.03%]
OP-1注射在牵张成骨兔模型中增加VEGF表达但不影响血管生成
Manuela Mandu-Hrit,Erin Seifert,Maria Kotsiopriftis et al.
Manuela Mandu-Hrit et al.
We have previously shown that a single injection of rhBMP-7 (OP-1) applied to the regenerate early during distraction accelerates bone consolidation in a rabbit model of distraction osteogenesis. In the present study, we hypothesised that t...
Adenovirus-mediated expression of growth and differentiation factor-5 promotes chondrogenesis of adipose stem cells [0.03%]
腺病毒介导生长分化因子-5的表达促进脂肪来源干细胞软骨生成诱导及基因治疗效果
Gang Feng,Yuqing Wan,Gary Balian et al.
Gang Feng et al.
The repair of articular cartilage injuries is impeded by the avascular and non-innervated nature of cartilage. Transplantation of autologous chondrocytes has a limited ability to augment the repair process due to the highly differentiated s...
Distinct signaling pathways confer different vascular responses to VEGF 121 and VEGF 165 [0.03%]
不同的信号途径赋予VEGF121和VEGF165不同的血管反应
Yan Zhang,Minao Furumura,Eishin Morita
Yan Zhang
Vascular endothelial growth factor (VEGF) is a pleiotropic factor that regulates embryonal vasculogenesis, tumor angiogenesis and vascular permeability. Among eight differential isoforms, VEGF 121 mainly regulates vascular permeability, whi...
Treatment with granulocyte colony stimulating factor is associated with improvement in endothelial function [0.03%]
粒系集落刺激因子治疗与内皮功能改善有关
Ignatios Ikonomidis,Christos Papadimitriou,Georgia Vamvakou et al.
Ignatios Ikonomidis et al.
Primary objective: Granulocyte-colony stimulating factor (G-CSF) is used for the mobilization of bone marrow and endothelial progenitor cells, though G-CSF-induced inflammation may cause endothelial dysfunction. We examin...
Randomized Controlled Trial
Growth factors (Chur, Switzerland). 2008 Jun;26(3):117-24. DOI:10.1080/08977190802090614 2008