Exploring the mechanisms of Shugan-Jieyu-Jianpi formula against irritable bowel syndrome combined with non-alcoholic fatty liver disease by network pharmacology and experimental validation [0.03%]
网络药理学结合实验验证法探讨疏肝解郁健脾方治疗伴非酒精性脂肪肝的肠易激综合征的作用机制
Xiaowen Yu,Xuan Chen,Jun Ouyang et al.
Xiaowen Yu et al.
The study was aimed to investigate the clinical effect and mechanism of Shugan-Jieyu-Jianpi (SGJYJP) formula for the treatment of irritable bowel syndrome (IBS) combined with non-alcoholic fatty liver disease (NAFLD). The clinical efficacy ...
GDF15 promotes corneal neovascularization and RB cell progression via AKT/ERK signal pathway [0.03%]
GDF15通过AKT/ERK信号途径促进角膜新生血管化和RB细胞增殖
Haijian Zheng,Wen Zheng,Shiliang Cheng et al.
Haijian Zheng et al.
In this study, we aim to explore the involvement of growth differentiation factor 15 (GDF15) in both corneal neovascularization (CNV) and retinoblastoma (RB) progression. Cell migration and proliferation were assessed through Scratch assays...
Evaluating growth-factor release in leukocyte- and platelet-rich fibrin, advanced platelet-rich fibrin, and injectable platelet-rich fibrin protocols: a narrative review [0.03%]
评价富含白细胞和血小板的纤维蛋白、先进血小板浓缩物和可注射富血小板纤维蛋白制备方案中生长因子释放：综述性评论
G A Alsabri,F van der Horst,S A Alkaabi et al.
G A Alsabri et al.
Since its introduction in 2001, multiple platelet-rich fibrin (PRF) centrifugation protocols have emerged, but the variations in growth factor release that result from these protocols remain unclear. This review aimed to evaluate growth fac...
Role of leptin and Insulin like growth Factor-1 In regulation of growth in children with congenital cyanotic heart disease [0.03%]
先天性青紫型心脏病儿童生长介素和胰岛素样生长因子-1的动态变化及相互关系研究
Ashraf A Elsharkawy,Amany K El-Hawary,Gehan A AlSawah et al.
Ashraf A Elsharkawy et al.
Background: Congenital cyanotic heart disease (CHD) in children is associated with several complications, amongst these complications is growth retardation which is believed to be multifactorial. ...
Plasma levels and diagnostic utility of VEGF, MMP-9 and TIMP-2 in the diagnosis of psoriasis forms [0.03%]
血管内皮生长因子、基质金属蛋白酶和组织金属蛋白酶抑制因子诊断银屑病的临床价值研究
Imen Chihaoui,Arbia Abbes,Wiem Zidi et al.
Imen Chihaoui et al.
Psoriasis pathogenisis remain unknown despite the fact that it is considered as the most common autoimmune skin disease. We raised the hypothesis whether the selected biomarkers in this study provide actual evidence of psoriasis presence an...
Platelet-rich plasma promotes wound repair in diabetic foot ulcer mice via the VEGFA/VEGFR2/ERK pathway [0.03%]
富血小板血浆通过VEGFA/VEGFR2/ERK途径促进糖尿病足溃疡小鼠伤口愈合
Weiqiang Wei,Di Xu,Fan Hu et al.
Weiqiang Wei et al.
Diabetic foot ulcers (DFUs) are a severe microvascular complication. Platelet-rich plasma (PRP) pitches in DFU treatment. This study explored the mechanism of PRP facilitating wound repair in DFU mice via vascular endothelial growth factor ...
The codon optimised gene produces an active human basic fibroblastic growth factor in rice cell suspension culture [0.03%]
密码子优化基因在悬浮培养的水稻细胞中产生人碱性成纤维细胞生长因子
Meysam Bastami,Ramin Hosseini
Meysam Bastami
The coding sequence of human basic fibroblast growth factor (hbFGF) was optimised for expression in rice. An expression cassette was constructed by fusing the PCR-amplified RAmy3D promoter, along with its 5'UTR, 3'UTR, and terminator sequen...
PDGF-induced internalisation promotes proteolytic cleavage of PDGFRβ in mesenchymal cells [0.03%]
PDGF诱导的内吞作用促进成纤维细胞生长因子受体-PDGF-Rβ在间充质细胞中的蛋白水解剪切反应
Marie Rubin Sander,Agni Karolina Tsiatsiou,Kehuan Wang et al.
Marie Rubin Sander et al.
Platelet-derived growth factor (PDGF)-induced signalling via PDGF receptor β (PDGFRβ) leads to activation of downstream signalling pathways which regulate multiple cellular responses. It is unclear how PDGFRβ is degraded; both lysosomal ...
Tibial transverse transport combined with platelet-rich plasma sustained-release microspheres activates the VEGFA/VEGFR2 pathway to promote microcirculatory reconstruction in diabetic foot ulcer [0.03%]
富血小板血浆缓释微球结合胫骨横向搬运激活VEGFA/VEGFR2通路促进糖尿病足溃疡微循环重建
Weiqiang Wei,Tenglong Jiang,Fan Hu et al.
Weiqiang Wei et al.
This study proposes to investigate the therapeutic efficacy and mechanism of combining tibial transverse transport (TTT) with platelet-rich plasma (PRP) for diabetic foot ulcer (DFU). The diabetic rabbit model was constructed with Streptozo...
L-Glutamine mitigates bile acid-induced inhibition of growth factor activity in rat hepatocyte cultures [0.03%]
L-谷氨酰胺能缓解胆酸对肝细胞生长因子活性的抑制作用
Wafa&#x;a Alqabandi,Gursev S Dhaunsi
Wafa&#x;a Alqabandi
Bile acid-induced hepatotoxicity is inevitable in Cholestasis pathogenesis and L-Glutamine (L-Gln) has been reported to prevent total parenteral nutrition (TPN)-induced cholestasis in premature neonates. While mechanisms remain unknown, we ...