Effect of autologous growth factors on apoptosis and thickness of the outer nuclear layer in an experimental retinal degeneration model [0.03%]
自体生长因子对视网膜退行性变模型凋亡及外核层厚度影响的研究
Emin Ozmert,Sibel Demirel,Umut Arslan et al.
Emin Ozmert et al.
Retinal pigment epithelium and photoreceptor cells are a microenvironment where 90 different peptides are synthesized for transduction, visual cycle, intracellular electron transport chain, and removal of metabolic wastes. Depending on the ...
Effects of galectin-1 on immunomodulatory properties of human monocyte-derived dendritic cells [0.03%]
人单核细胞来源的树突状细胞的免疫调节特性受半乳糖凝集素-1的影响
Tanja Džopalić,Miloš Kostić,Milena Kostić et al.
Tanja Džopalić et al.
Our study aimed to evaluate the effects of Gal-1 in dose depending manner on maturation and immunomodulatory properties of monocyte-derived (Mo) DCs in-vitro. The effects were analyzed by monitoring their phenotypic characteristics, cytokin...
Application of bioinformatics and molecular dynamics simulation approaches for identification of fibroblast growth factor 10 analogues with potentially improved thermostability [0.03%]
生物信息学和分子动力学模拟在寻找热稳定性更好的成纤维细胞生长因子10类似物中的应用
Ali Akbar Alizadeh,Behzad Jafari,Siavoush Dastmalchi
Ali Akbar Alizadeh
Fibroblast growth factor 10 functions as a paracrine mesenchymal molecule to initiate signalling pathways regarding to cellular development and health. However, the low thermal stability restricts it's functionality in the human body and th...
Increased levels of the cardiovascular disease risk biomarkers GDF15 and myostatin in patients with chronic lymphocytic leukemia [0.03%]
慢性淋巴细胞性白血病患者心血管疾病风险生物标志物GDF15和myostatin水平升高
Karin Larsson,Martin Höglund,Anders Larsson et al.
Karin Larsson et al.
Individuals suffering from cancer, including hematological malignancies, are at increased risk of cardiovascular disease (CVD). Elevated levels of several biomarkers in blood are associated with an increased risk of CVD. The aim of this stu...
Interactions between thymic endothelial cells and thymocytes are influenced by growth hormone [0.03%]
生长激素影响胸导管内皮细胞和胸腺细胞间的相互作用
Marvin Paulo Lins,Iana Mayane Mendes Nicácio Viana,Salete Smaniotto et al.
Marvin Paulo Lins et al.
Growth hormone (GH), in addition to its classic actions on growth and metabolism in the body, exerts pleiotropic effects on the immune system, particularly on the thymus. The aim of this study was to evaluate the influence of GH on the inte...
Immunohistochemical evaluation of the prognostic and predictive power of epidermal growth factor receptor ligand levels in patients with metastatic colorectal cancer [0.03%]
评估表皮生长因子受体配体在转移性结直肠癌患者中的预后和预测价值的免疫组化分析
Siavash Foroughi,Ryan A Hutchinson,Hui-Li Wong et al.
Siavash Foroughi et al.
For patients with metastatic colorectal cancer (mCRC), epidermal growth factor receptor (EGFR) inhibitors are limited to patients with RAS wild-type tumours. Not all patients will benefit from treatment and better predictive biomarkers are ...
Platelet rich plasma efficiently substitutes the beneficial effects of serum during in vitro oocyte maturation and helps maintain the mitochondrial activity of maturing oocytes [0.03%]
富血小板血浆可有效替代体外卵母细胞成熟的胎牛血清并有助于维持成熟卵母细胞的线粒体活性
F Moulavi,R T Akram,S Khorshid Sokhangouy et al.
F Moulavi et al.
Platelets contain most of the potent mitogenic factors present in serum and follicular fluid and intraovarian injection of autologous platelet rich plasma (PRP) was shown to improve ovarian function and development of preantral follicles. T...
Attenuating influenza a virus infection by heparin binding EGF-like growth factor [0.03%]
肝素结合EGF样生长因子削弱甲型流感病毒感染
K M Lai,B H Goh,W L Lee
K M Lai
Cell entry of influenza A virus (IAV) was reported to be promoted by epidermal growth factor receptor (EGFR). On the other hand, binding of heparin-binding EGF-like growth factor (HB-EGF) to EGFR leads to internalisation and degradation of ...
Exploring the role of oxidative stress, fatty acids and neurotrophins in gestational diabetes mellitus [0.03%]
探讨氧化应激、脂肪酸和神经营养因子在妊娠糖尿病中所扮演的角色
Anjali Jadhav,Amrita Khaire,Sadhana Joshi
Anjali Jadhav
Gestational diabetes mellitus (GDM) constitutes an unfavorable intrauterine environment for embryonic and feto-placental development. Women with GDM are at higher risk for materno-fetal complications and placental abnormalities. The placent...
Effects of platelet-rich plasma on the pancreatic islet survival and function, islet transplantation outcome and pancreatic pdx1 and insulin gene expression in streptozotocin-induced diabetic rats [0.03%]
富血小板血浆对链脲佐菌素诱导的糖尿病大鼠胰岛移植存活率、功能及PDX1和胰岛素基因表达的影响
Marzieh Nemati,Narges Karbalaei,Pooneh Mokarram et al.
Marzieh Nemati et al.
Platelet-rich plasma (PRP) is a therapeutic option in different fields based on its growth factors. We investigated influence of PRP on islet survival, function, transplantation outcomes, and pancreatic genes expression in diabetic rats. In...