Coarse-grained Simulations of the Impact of Chain Length and Stiffness on the Formation and Aggregation of Polyelectrolyte Complexes [0.03%]
聚合物链长度和刚度对聚电解质复合物形成和聚集的影响的粗粒化模拟研究
Caleb E Gallops,Jesse D Ziebarth,Yongmei Wang
Caleb E Gallops
Polyelectrolyte complexes formed from nucleic acids and synthetic polycations have been studied because of their potential in gene delivery. Coarse-grained molecular dynamics simulations are performed to examine the impact of chain length a...
Logical Analysis of Data in Structure-Activity Investigation of Polymeric Gene Delivery [0.03%]
逻辑数据分析在聚合基因传递结构活性研究中的应用
Anna V Gubskaya,Tiberius O Bonates,Vladyslav Kholodovych et al.
Anna V Gubskaya et al.
To date semi-empirical or surrogate modeling has demonstrated great success in the prediction of the biologically relevant properties of polymeric materials. For the first time, a correlation between the chemical structures of poly(β-amino...