Curcumin reduces the pathogenicity of Streptococcus suis serotype 2 in mice by targeting suilysin [0.03%]
姜黄素通过作用于Sly基因降低乙型溶血性链球菌的致病性
Jiafei Zhan,Jieying Xia,Jiaxin Ma et al.
Jiafei Zhan et al.
Background: Streptococcus suis (S. suis) is a significant zoonotic pathogen, with serotype 2 (SS2) being the most prevalent. Suilysin (SLY), an essential toxin indicator for S. suis, is crucial in the infections caused by...
L-citrulline modulates pancreatic enzyme activity and biochemical markers in adult female Wistar rats with metabolic syndrome [0.03%]
L-瓜氨酸调节代谢综合征成年雌性威斯特大鼠的胰腺酶活性和生化标志物
Adamu Imam Isa,Hanan Eissa,Mohamed-Nabih Abd-El Rahman et al.
Adamu Imam Isa et al.
Background: Metabolic syndrome (MetS) induces profound pancreatic damage characterised by oxidative stress and chronic inflammation. Objectives: ...
Hormonal therapies for post-abortion uterine recovery: Comparison of estradiol ± dydrogesterone, transdermal estradiol gel and combined oral contraceptives [0.03%]
人工流产后的激素治疗：雌二醇联合地屈孕酮与口服避孕药及雌二醇凝胶的比较研究
Qin Huang,Hai Luo,Xi Dou et al.
Qin Huang et al.
Background: Induced abortion can impair endometrial repair, increasing risks for infertility. This study directly compared three hormonal regimens for enhancing post-abortion uterine recovery. ...
Randomized Controlled Trial
Pakistan journal of pharmaceutical sciences. 2026 Jul;39(7):2210-2217. DOI:10.36721/PJPS.2026.39.7.208.1 2026
Effects of curcumin on the signal transducer and activator of transcription 3 signaling pathway and bile acid enterohepatic circulation in liver cancer mice model [0.03%]
姜黄素对肝癌小鼠模型STAT3信号通路及胆汁酸肠肝循环的影响
Na Hu,Niu Yan,Tingting Zhao et al.
Na Hu et al.
Background: Liver cancer has a high incidence and poor prognosis. Curcumin is a natural compound with anti-tumor activity, but its effects on the STAT3 signaling pathway and the bile acid enterohepatic circulation in live...
Biological synthesis of silver nanoparticles using extracts from Citrullus colocynthis and their anticancer activity [0.03%]
采用葫芦巴提取物生物合成的银纳米颗粒及其抗肿瘤活性研究
Nehad S Alsubhi
Nehad S Alsubhi
Background: Green synthesis of silver nanoparticles (AgNPs) using plant extract has emerged as an eco-friendly alternative to conventional chemical methods, offering potential biomedical applications, particularly in canc...
TLR9 agonists alleviate diabetic condition by promoting the maturation of differentiated bone marrow mesenchymal stem cells in rats [0.03%]
toll样受体9激动剂通过促进糖尿病大鼠骨髓间充质干细胞的成熟来改善胰岛素抵抗和β细胞功能障碍
Chuan Liu,Huayong Zheng,Peng Lu et al.
Chuan Liu et al.
Background: Current diabetes therapies often fail to address the loss of insulin-producing β-cells. Bone marrow mesenchymal stem cells (BMSCs) can differentiate into insulin-producing cells (IPCs), but functional maturit...
Short-term comparative effects of semaglutide, either alone or in conjunction with canagliflozin, on early diabetic kidney disease [0.03%]
利司那肽或联合卡格列净对早期糖尿病肾脏病的短期效应比较研究
Wang Long,Li Ningning,Huang Weijun
Wang Long
Background: Diabetic kidney disease (DKD) is a common complication of type 2 diabetes mellitus and an important cause of end-stage renal disease. Metabolic dysfunction, albuminuria, and chronic low-grade inflammation char...
Randomized Controlled Trial
Pakistan journal of pharmaceutical sciences. 2026 Jul;39(7):2165-2172. DOI:10.36721/PJPS.2026.39.7.204.1 2026
Enhanced external counterpulsation (EECP) augmentation of amlodipine in elderly patients with isolated systolic hypertension (ISH) and wide pulse pressure: A comparative study [0.03%]
强化体外反搏(ECP)增强氨氯地平治疗老年人单纯收缩期高血压(ISH)和脉压变大：一项比较研究
Meili Ding,Jun Zhang,Zuliang Li et al.
Meili Ding et al.
Background: Geriatric patients with isolated systolic hypertension (ISH) and wide pulse pressure (PP) were treated using enhanced external counter pulsation (EECP) combined with amlodipine versus amlodipine alone. ...
miR-152-3p inhibits triple-negative breast cancer cell progression by targeting signal transducer and activator of transcription 3, nuclear factor kappa B subunit p65 and adenylate cyclase 6 [0.03%]
微RNA-152-3p通过靶向信号转导及转录激活蛋白3，核因子κB亚基p65和腺苷酸环化酶6抑制三阴性乳腺癌细胞发展进展
Yan Cheng,Yingyao Quan
Yan Cheng
Background: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and currently lacks defined therapeutic targets. Although miR-152-3p functions as a tumor suppressor in various cancers, its sp...
Activity based insights into the seed proteins of Datura alba from Pakistan [0.03%]
基于活动的巴基斯坦神圣杜鹃花种子蛋白研究新见解
Tehreem Abdul Hameed,Laraib Batool,Ifrah Siddiqui et al.
Tehreem Abdul Hameed et al.
Background: There are fifteen species of Datura, a perennial shrub-like herb, with Datura alba (D. alba) being the most important medicinal plant because of its therapeutic and aesthetic uses. Pharmaceutical goods use fre...