Clinical significance of FoxO1 expression and its regulation in dihydroartemisinin treatment in liver cancer [0.03%]
双氢青蒿素治疗肝癌过程中FoxO1表达及其调控的意义
Yi Yu,Shenjin Lai,Youxi Zhou et al.
Yi Yu et al.
Background: The transcription factor Forkhead Box O 1 (FoxO1) is crucial to numerous cellular and biological functions. Dihydroartemisinin (DHA) is a derivative of artemisinin extracted from Chinese medicinal plants. The ...
Protective effect of pituitrin combined with norepinephrine on cardiopulmonary injury in patients with septic shock diagnosed by critical care ultrasound evaluation [0.03%]
垂体后叶素联合去甲肾上腺素通过重症超声评估在脓毒性休克心肺保护中的作用研究
Henghao Cui,Xiaochun Yuan,Kai Lu et al.
Henghao Cui et al.
Background: Septic shock is a life-threatening complication of sepsis, often accompanied by cardiopulmonary dysfunction, which significantly increases the mortality of patients. Norepinephrine (NE) is a commonly used vaso...
Randomized Controlled Trial
Pakistan journal of pharmaceutical sciences. 2026 Mar;39(3):878-886. DOI:10.36721/PJPS.2026.39.3.REG.12881.1 2026
Review: Amarogentin: A review of its pharmacology, pharmacokinetics and toxicity [0.03%]
苦马豆素研究进展:药理学、毒理学及代谢动力学综述
Ying Tan,Dongmei Zhang,Wei Xiong et al.
Ying Tan et al.
This review provides a comprehensive analysis of Amarogentin (AMA), a secoiridoid glycoside from the Gentianaceae family, highlighting its significant pharmacological effects. AMA demonstrates liver protection, anticancer, anti-inflammatory...
Design and optimization of ibuprofen microemulgel using phase titration for effective and enhanced dermal drug delivery [0.03%]
采用相滴定法设计和优化布洛芬微乳凝胶以实现有效经皮给药
Amna Nosheen Jaweria,Sehar Khalid,Maiza Mubashaar et al.
Amna Nosheen Jaweria et al.
Background: The oral administration of ibuprofen is limited due to gastrointestinal adverse effects and inadequate solubility, necessitating the development of enhanced cutaneous delivery systems. ...
GC-MS correlated-antiepileptic screening for probable GABA-modulator by PTZ-induced acute seizure model in Swiss albino mice and phytochemical profiling of ethanol extract of Ficus benghalensis [0.03%]
茋的乙醇提取物的植物化学分析及其通过PTZ诱导的小鼠急性惊厥模型的相关抗癫痫作用(可能调节GABA)的GC-MS筛选研究
Sulaman Yaqub,Muhammad Islam,Abrar Ahmad et al.
Sulaman Yaqub et al.
Background: Plants, such as Ficus benghalensis (family: Moraceae), contain diverse phytoconstituents against diseases, including epilepsy, affecting more than 50 million people worldwide and is characterized by high neuro...
Momordica charantia L. extracts restores ovarian function in Estradiol-induced polycystic ovarian syndrome in rats [0.03%]
苦瓜提取物对雌二醇致多囊卵巢综合征大鼠卵巢功能的改善作用研究
Anosh Tahir,Saira Saeed Khan,Sadaf Naeem et al.
Anosh Tahir et al.
Background: This study investigated the therapeutic potential of aqueous fruit and seed extract of Momordica charantia L. (MC) as an alternative treatment for PCOS. ...
Preliminary formulation studies of water-soluble granules of Hibiscus sabdariffa calyx [0.03%]
Hibiscus sabdariffa花萼水溶性颗粒初步研究
Zwanden Sule Yahaya,Dorcas Ayimiti Danladi,Boma Blessing Mohammed et al.
Zwanden Sule Yahaya et al.
Background: The formulation of Hibiscus sabdariffa, a plant reported to have hypoglycemic, antihypertensive, antibacterial, antioxidant and anti-inflammatory properties, into a suitable dosage form is vital in improving p...
Effect of linezolid combined with N-acetylcysteine on lung function, blood gas and inflammation in patients with severe pneumonia [0.03%]
利奈唑胺联合N-乙酰半胱氨酸对严重肺炎患者肺功能、血气及炎症的影响
Xiaoyan Bai,Yao Luo,Jiajia Huang et al.
Xiaoyan Bai et al.
Background: Severe pneumonia is a serious lung disease. The continuous and regular administration of antibiotics is currently used for severe pneumonia. However, the single antibiotic may enhance the drug resistance and t...
Monosodium L-glutamate affects orthodontic outcomes by inhibiting hypothalamic-pituitary-gonadal axis function [0.03%]
谷氨酸单钠影响下丘脑-垂体-性腺轴功能从而影响牙齿正畸效果
Xiaofang Cai,Min Cai,Yuxiao Zhao et al.
Xiaofang Cai et al.
Background: Orthodontic treatment involves complex bone remodeling, with the Osteoprotegerin (OPG)/Receptor Activator of nuclear factor Kappa-B Ligand (RANKL)/Receptor activator of nuclear factor Kappa-B (RANK) (OPG/RANKL...
Celecoxib in combination with foot and ankle orthoses for the treatment of acute ankle injuries: A study on the correlation between anti-inflammatory and analgesic mechanisms and functional recovery [0.03%]
联合使用塞来昔布与足踝矫形器治疗急性踝关节扭伤的抗炎镇痛机制及其对功能恢复影响的相关性研究
Qilong Hu,Dan Hu,Fengxi Qiu et al.
Qilong Hu et al.
Background: Celecoxib combined with an ankle orthosis is widely used in the treatment of acute ankle injuries. However, details of local adverse reactions such as skin lesions and tenderness related to the orthosis are un...
Randomized Controlled Trial
Pakistan journal of pharmaceutical sciences. 2026 Mar;39(3):783-791. DOI:10.36721/PJPS.2026.39.3.REG.15523.1 2026