[Analysis of VWF Gene c.7332G>A Nonsense Mutation Pedigree and Study of Molecular Pathogenesis] [0.03%]
血管性血友病基因c.7332G>A终止密码突变家系分析及分子发病机制研究
Duan-Yang Wang,Lei Wang,Dong-Yan Fu et al.
Duan-Yang Wang et al.
Objective: To analyze the genetic characteristics of the VWF gene c. 7332G>A nonsense mutation and explore its molecular pathogenesis. Methods: ...
[The Mechanism of Echinococcus Granulosus Sensu Stricto Antigen B to Protect Immune Thrombocytopenia Mouse Model by Influencing Autophagy] [0.03%]
细粒棘球绦虫抗原B调控自噬影响免疫性血小板减少症小鼠模型的作用机制研究
Hai-Chen Song,Xue-Mei Wang,Dan-Lui Li et al.
Hai-Chen Song et al.
Objective: To investigate the mechanism of natural antigen B (nAgB) to protect Immune thrombocytopenia (ITP) mouse model by influencing autophagy. Methods...
[Application of VWF Antigen and Activity Testing Based on ABO Blood Group in Risk Assessment of Deep Vein Thrombosis] [0.03%]
基于ABO血型的VWF抗原和活性检测在深静脉血栓风险评估中的应用
Bin Yan,Tian-Xi Hu,Sha Li et al.
Bin Yan et al.
Objective: To explore the clinical value of plasma von Willebrand factor antigen (VWF:Ag) and VWF activity (VWF:GPIbM) based on ABO blood group in the risk assessment of deep vein thrombosis (DVT). ...
[The Epigenetic Regulation of Decitabine Resistance in TP53 -Mutated Myelodysplastic Syndromes: Integrated Analysis Based on RNA-seq and Methylomics] [0.03%]
地西他滨耐药的TP53突变型骨髓增生异常综合征表观遗传调控机制的整合分析研究（基于RNA测序和甲基组学）
Lan Zhang,Yu-Ye Ren,Wei Chen et al.
Lan Zhang et al.
Objective: To investigate the effects of TP53 genetic status (wild-type/mutated/null) on the drug resistance of decitabine (DAC) in myelodysplastic syndromes (MDS) and identify key resistance-associated genes. ...
[Correlation between ASXL1 Gene Mutation Characteristics and Clinical Manifestations and Prognosis in Patients with Myelodysplastic Syndrome] [0.03%]
ASXL1基因突变特征与骨髓增生异常综合征患者临床表现及预后的相关性分析
Jia-Le Ma,Yang Wang,Xue-Bao Teng et al.
Jia-Le Ma et al.
Objective: To explore the correlation between ASXL1 gene mutation characteristics and clinical manifestations and prognosis in patients with myelodysplastic syndrome (MDS). ...
[Metabolic Characteristics of Multiple Myeloma Based on Non-Targeted Metabolomics] [0.03%]
基于非靶向代谢组学的多发性骨髓瘤代谢特征分析
Han-Ke Wang,Yan Jiang,Yan-Yan Zhang et al.
Han-Ke Wang et al.
Objective: Non-targeted metabolomics based on ultra-performance liquid chromatography mass spectrometry (UPLC-MS) platform was used to study the metabolic characteristics of multiple myeloma (MM) patients, and explore pot...
[Analysis of Risk Factors for Early Relapse/Progression in Patients with Multiple Myeloma and Development of a Nomogram Prediction Model] [0.03%]
多发性骨髓瘤患者早期复发/进展的风险因素分析及预后列线图模型的建立
Mei-Jiao Huang,Yu Liu,Hong-Yan Wang et al.
Mei-Jiao Huang et al.
Objective: To analyze the potential risk factors for early relapse/progression in patients with multiple myeloma (MM) and develop a risk prediction model based on these factors. ...
[Clinical Study of MiR-125b-5p/HIF-1α Pathway in Involvement of Vitamin D Deficiency in Pathogenesis of Multiple Myeloma] [0.03%]
维生素D缺乏通过MiR-125b-5p/HIF-1α信号通路参与多发性骨髓瘤发病的临床研究
Qian-Song Cheng,Jing-Jing Zhou,Feng Guo et al.
Qian-Song Cheng et al.
Objective: To detect the serum levels of 25(OH)D, miR-125b-5p, hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor A (VEGFA) in patients with multiple myeloma (MM), and explore the role of miR-12...
[Clinical Analysis of Ixazomib-Based Chemotherapy Regimens in the Treatment of Newly Diagnosed Multiple Myeloma with 1q21 Amplification] [0.03%]
伊沙佐米为基础的化疗方案治疗1q21拷贝数增加的新诊断多发性骨髓瘤患者的临床分析
Dan-Xia Lin,Yan-Hong Zhuang,Jian Tang et al.
Dan-Xia Lin et al.
Objective: To clarify the prognostic significance of 1q21 amplification in multiple myeloma (MM), and explore the efficacy and prognosis of ixazomib in the treatment of MM patients with 1q21 amplification. ...
[Analysis of Clinical Characteristics and Risk Factors for Bone Lesions in Patients with Multiple Myeloma] [0.03%]
多发性骨髓瘤患者骨病的临床特征及危险因素分析
Chen-Yang Li,Qi-Ke Zhang,Xiao-Fang Wei et al.
Chen-Yang Li et al.
Objective: To investigate the clinical characteristics of patients with multiple myeloma (MM) complicated by bone lesions and the risk factors associated with bone lesions. ...