[Study on the Resistance Mechanism of Blinatumomab in the Treatment of Acute Lymphoblastic Leukemia--Review] [0.03%]
拜西妥单抗治疗急性淋巴细胞白血病耐药机制的研究进展
Xiao-Rui Jing,Juan Cheng
Xiao-Rui Jing
Blinatumomab is the first globally approved bispecific T cell engager targeting the B-cell surface antigen CD19, and numerous clinical trials have demonstrated its significant efficacy in B-acute lymphoblastic leukemia (B-ALL) patients. How...
[Research Progress on Indicators of Red Blood Cell Storage Lesions--Review] [0.03%]
红细胞储存损伤指标的研究进展-综述
Ke-Yu He,Qiang Zhang,Bao-Yu Wang et al.
Ke-Yu He et al.
Red blood cell (RBC) transfusion is primarily utilized for the treatment of anemia resulting from various causes, and the quality of stored RBCs (sRBCs) is crucial to the efficacy of transfusion therapy. As storage duration increases, the q...
[Cellular Senescence in Hematological Malignancies: Pathogenesis and Traditional Chinese Medicine Treatment Strategies--Review] [0.03%]
血液系统恶性肿瘤的细胞衰老机制及中医药干预策略研究进展
Ming-Yi Wang,Xue-Jun Zhu
Ming-Yi Wang
Cellular senescence is fundamentally characterized as an irreversible cell cycle arrest state. Studies have revealed that cellular senescence plays a significant role in the pathogenesis and progression of hematological malignancies. Conseq...
[Advances in the Study of Factors Influencing the Efficacy of CAR-T Cell Therapy in Hematologic Oncology Treatment--Review] [0.03%]
CAR-T细胞治疗血液系统肿瘤疗效影响因素的研究进展-综述
Li-Mei Li,Xun Lai,Hong-Jing Yin
Li-Mei Li
Chimeric antigen receptor T cell (CAR-T) therapy is a revolutionary progress in the current field of tumor treatment, especially showing remarkable potential in relapsed/refractory hematological malignancies. However, there are significant ...
[Research Progress on Epigenetic Regulation of the Leukemia Microenvironment --Review] [0.03%]
[白血病微环境表观遗传调控的研究进展-综述]
Bo-Han Liu,Xue-Zhong Zhang,Fei-Fei Yang
Bo-Han Liu
The development and progression of leukemia are driven not only by intrinsic genetic and epigenetic alterations in leukemia cells, but also by the dynamic remodeling of immune niches within the bone marrow microenvironment (BMM). Accumulati...
[Research Progress of CDK Inhibitors in Acute Myeloid Leukemia --Review] [0.03%]
[细胞周期蛋白依赖性激酶在急性髓系白血病中的研究进展-综述]
Yi-Fan Liu,Hui Liu
Yi-Fan Liu
Acute myeloid leukemia (AML) is a highly heterogeneous disease. This heterogeneity often leads to treatment failure or unsustainable efficacy, and high relapse rates as well as short progression-free survival (PFS) are closely associated wi...
[Prognostic Factors in Children with Hemophagocytic Lymphohistiocytosis: A Retrospective Cohort Study] [0.03%]
儿童噬血细胞综合征预后因素分析：队列研究
Yan Liu,Xin Luo,Hong Liu et al.
Yan Liu et al.
Objective: To investigate the factors associated with prognosis in children diagnosed with hemophagocytic lymphohistiocytosis (HLH). Methods: ...
[The Impact of Nutritional Intervention on Complications and Prognosis of Hematopoietic Stem Cell Transplantation Patients] [0.03%]
营养干预对造血干细胞移植患者并发症及预后影响的研究
Gui-Ju Zheng,Meng-Yuan Yue,Guo-Qiang Lin et al.
Gui-Ju Zheng et al.
Objective: To investigate the effects of nutritional supportive therapy on hematopoietic stem cell transplantation (HSCT) patients and to analyze its relationship with post-transplant hematopoietic reconstitution, acute g...
[Clinical Phenotype and Molecular Pathogenesis of a Hereditary Hemochromatosis Family with Double-Site Mutations in SLC40A1] [0.03%]
SLC40A1双位点突变遗传性血色素沉着症家系的临床表型及分子病理学研究
Chuan-Dong Hou,Jie Geng,Ya-Jing Zhang et al.
Chuan-Dong Hou et al.
Objective: To investigate the clinical phenotype and molecular pathogenesis of a hereditary hemochromatosis family with double-site mutations in SLC40A1 . ...
[Clinical Characteristics, Drug Resistance, and Prognosis Analysis of Enterobacteriaceae Bloodstream Infection in Children with Acute Leukemia] [0.03%]
儿童急性白血病肠杆菌科血流感染的临床特征、耐药性及预后分析
Shu-Xian Huang,Chun-Ping Wu,Shao-Hua LE et al.
Shu-Xian Huang et al.
Objective: To investigate the clinical characteristics, drug resistance and prognosis of Enterobacteriaceae bloodstream infection (BSI) in children with acute leukemia (AL) following chemotherapy. ...