[Research Progress on the Bone Marrow Microenvironment in Beta-Thalassemia --Review] [0.03%]
β-珠蛋白生成障碍性贫血骨髓微环境研究进展及相关机制思考——文献复习
Xin Peng,Ya-Jie Wang,Zeng-Zheng Li et al.
Xin Peng et al.
Thalassemia is one of the most common and harmful single-gene recessive disorders in the clinic. It is characterized by impaired or absent production of one globin chain of hemoglobin in adults. The most common form is beta-thalassemia, whi...
[Research Progress of CAR-T Cell Therapy in Autoimmune Diseases --Review] [0.03%]
CAR-T细胞治疗自身免疫病的研究进展——综述
Qiang Xiong,Fei Li
Qiang Xiong
Chimeric antigen receptor T (CAR-T) cell therapy has achieved significant success in the field of hematologic oncology. Considering the similarities in the origin and circulatory distribution between hematopoietic tumor cells and autoantige...
[Research Progress of Chimeric Antigen Receptor T Cell Therapy in Acute Myeloid Leukemia--Review] [0.03%]
嵌合抗原受体T细胞治疗急性髓系白血病的研究进展-综述性论文
Shu-Ya Ge,Jian-Jun Bian,Lei Shen et al.
Shu-Ya Ge et al.
Chimeric antigen receptor (CAR) T cell immunotherapy has achieved significant clinical efficacy in lymphatic malignancies, and CAR-T therapy for acute myeloid leukemia (AML) has become a research hotspot in recent years. At present, there i...
[Research Progress in Venetoclax-Based Combination Therapy in Acute Myeloid Leukaemia--Review] [0.03%]
基于维奈克拉的急性髓系白血病联合用药治疗研究进展——文献复习
Jia-Qi Chen,Ying-Hua Geng
Jia-Qi Chen
Acute myeloid leukemia (AML) can be transformed by the malignant transformation of hematopoietic progenitor cells at different stages of normal myeloid cell differentiation and development, thus leading to infection, anemia, bleeding sympto...
[Advances in the Treatment of Acute Myeloid Leukemia with TP53 Mutations-Review] [0.03%]
染色体畸变急性髓系白血病治疗的新进展及挑战——文献综述
Yan-Han Zhou,Pei-Pei Ye
Yan-Han Zhou
Acute myeloid leukemia (AML) is the most common hematological malignancies in adults. TP53, as a tumor suppressor gene, has a mutation rate of about 5%-10% in AML patients. In 2017, the European Leukemia Net first classified AML with TP53 m...
[Analysis of Risk Factors and Clinical Characteristics of Early Death in Patients with Hemophagocytic Syndrome] [0.03%]
[噬血细胞综合征患者早期死亡的风险因素及临床特征分析]
Meng-Ting Ma,Jie Feng,Nan Wu et al.
Meng-Ting Ma et al.
Objective: To investigate the clinical features and related risk factors of early death of adult hemophagocytic lymphohistiocytosis (HLH). Methods: ...
[Clinical Characteristics and Prognostic Analysis of the Chronic Myelomonocytic Leukemia] [0.03%]
慢性粒单细胞白血病的临床特征和预后分析
Zhi-Min Yan,Xiao-Jun Chen,Yue Yin et al.
Zhi-Min Yan et al.
Objective: To analyze and explore the clinical characteristics and prognostic factors of chronic myelomonocytic leukemia (CMML), a rare hematological malignancy, thereby providing insights for basic research and clinical ...
[The Application of Human Lung Organoids for Assessing the Cyclophosphamide-Induced Pulmonary Toxicity and Potential Mechanisms] [0.03%]
[人肺类器官在环磷酰胺致肺毒性评估及机制探索中的应用]
Yi Di Wang,Xiao Tong Li,Heng Zhu et al.
Yi Di Wang et al.
Objective: To investigate Cyclophosphamide (CTX)-induced pulmonary toxicity using a human lung organoid model and explore its effects on DNA damage, inflammatory response, and early fibrosis. ...
[Biological Characteristics of Human Umbilical Cord Mesenchymal Stem Cells Transduced with a BMP4-Carrying Adenovirus] [0.03%]
人脐带间充质干细胞转染含BMP4腺病毒的生物学特性
Xiao-Yun Guan,Pei-Lin Li,Ying-Ying Wu et al.
Xiao-Yun Guan et al.
Objective: To evaluate the effects of Bone Morphogenetic Protein 4(BMP4) overexpression mediated by an adenoviral vector on immunophenotype features, migration ability, colony-forming ability, and early osteogenic differe...
[Embryonic Stem Cell-Derived Mesenchymal Stromal Cell Exosomes Protect Against Radiation-Induced Lymphocyte Injury and Its Related Mechanisms] [0.03%]
胚胎干细胞来源间充质基质细胞外泌体对放射线引起的淋巴细胞损伤的保护作用及机制研究
Jia-Xin Chen,Zhi-Qing Liu,Yang-Yang Lei et al.
Jia-Xin Chen et al.
Objective: To explore the repair effect and its related mechanism of exosomes derived from embryonic stem cell-induced mesenchymal stromal cells (ESC-MSC) on radiation-induced lymphocyte damage. ...