[TMSB4X Promotes Proliferation and Metastasis of T-cell Acute Lymphoblastic Leukemia Cells by Regulating the Wnt/β-catenin Signaling Pathway] [0.03%]
TMSB4X通过调节Wnt/β-catenin信号通路促进T细胞急性淋巴细胞白血病增殖和转移
Yi Hong,Yu Sun,Ming-Zhou Chen et al.
Yi Hong et al.
Objective: To investigate the expression of TMSB4X in T-cell acute lymphoblastic leukemia (T-ALL) cells, as well as its effects on T-ALL cell proliferation and metastasis and the underlying mechanisms. ...
[Analysis of Genetic Characteristics and Clinical Efficacy in Pediatric Acute Myeloid Leukemia with NUP98∷KDM5A Fusion Gene Positive] [0.03%]
NUP98-KDM5A阳性儿童急性髓系白血病的遗传特征及临床疗效分析
Huan-Huan Li,Xue Chen,Jing Long et al.
Huan-Huan Li et al.
Objective: To explore the genetic characteristics and clinical efficacy of pediatric acute myeloid leukemia (AML) with NUP98∷KDM5A fusion gene positive. ...
[The Clinical Significance of ARHGAP10 Alterations in Acute Myeloid Leukemia] [0.03%]
急性髓系白血病中ARHGAP10变异的临床意义
Ting-Ting DU,Zi-Jun Xu,Xiang-Mei Wen et al.
Ting-Ting DU et al.
Objective: To investigate the expression and methylation alterations of ARHGAP10 in AML and to further explore its clinical significance. Methods: ...
[Research Progress on the Bone Marrow Microenvironment in Beta-Thalassemia --Review] [0.03%]
β-珠蛋白生成障碍性贫血骨髓微环境研究进展及相关机制思考——文献复习
Xin Peng,Ya-Jie Wang,Zeng-Zheng Li et al.
Xin Peng et al.
Thalassemia is one of the most common and harmful single-gene recessive disorders in the clinic. It is characterized by impaired or absent production of one globin chain of hemoglobin in adults. The most common form is beta-thalassemia, whi...
[Research Progress of CAR-T Cell Therapy in Autoimmune Diseases --Review] [0.03%]
CAR-T细胞治疗自身免疫病的研究进展——综述
Qiang Xiong,Fei Li
Qiang Xiong
Chimeric antigen receptor T (CAR-T) cell therapy has achieved significant success in the field of hematologic oncology. Considering the similarities in the origin and circulatory distribution between hematopoietic tumor cells and autoantige...
[Research Progress of Chimeric Antigen Receptor T Cell Therapy in Acute Myeloid Leukemia--Review] [0.03%]
嵌合抗原受体T细胞治疗急性髓系白血病的研究进展-综述性论文
Shu-Ya Ge,Jian-Jun Bian,Lei Shen et al.
Shu-Ya Ge et al.
Chimeric antigen receptor (CAR) T cell immunotherapy has achieved significant clinical efficacy in lymphatic malignancies, and CAR-T therapy for acute myeloid leukemia (AML) has become a research hotspot in recent years. At present, there i...
[Research Progress in Venetoclax-Based Combination Therapy in Acute Myeloid Leukaemia--Review] [0.03%]
基于维奈克拉的急性髓系白血病联合用药治疗研究进展——文献复习
Jia-Qi Chen,Ying-Hua Geng
Jia-Qi Chen
Acute myeloid leukemia (AML) can be transformed by the malignant transformation of hematopoietic progenitor cells at different stages of normal myeloid cell differentiation and development, thus leading to infection, anemia, bleeding sympto...
[Advances in the Treatment of Acute Myeloid Leukemia with TP53 Mutations-Review] [0.03%]
染色体畸变急性髓系白血病治疗的新进展及挑战——文献综述
Yan-Han Zhou,Pei-Pei Ye
Yan-Han Zhou
Acute myeloid leukemia (AML) is the most common hematological malignancies in adults. TP53, as a tumor suppressor gene, has a mutation rate of about 5%-10% in AML patients. In 2017, the European Leukemia Net first classified AML with TP53 m...
[Analysis of Risk Factors and Clinical Characteristics of Early Death in Patients with Hemophagocytic Syndrome] [0.03%]
[噬血细胞综合征患者早期死亡的风险因素及临床特征分析]
Meng-Ting Ma,Jie Feng,Nan Wu et al.
Meng-Ting Ma et al.
Objective: To investigate the clinical features and related risk factors of early death of adult hemophagocytic lymphohistiocytosis (HLH). Methods: ...
[Clinical Characteristics and Prognostic Analysis of the Chronic Myelomonocytic Leukemia] [0.03%]
慢性粒单细胞白血病的临床特征和预后分析
Zhi-Min Yan,Xiao-Jun Chen,Yue Yin et al.
Zhi-Min Yan et al.
Objective: To analyze and explore the clinical characteristics and prognostic factors of chronic myelomonocytic leukemia (CMML), a rare hematological malignancy, thereby providing insights for basic research and clinical ...