[Genetic Analysis of a Chinese Pedigree with Hereditary Spherocytosis Caused by Copy Number Variation Deletion of SPTB Gene] [0.03%]
[SPTB基因拷贝数变异缺失引起的遗传性球形红细胞增多症家系的基因分析]
Xiang-Lei Chen,Jing-Gang Li,Qian Men et al.
Xiang-Lei Chen et al.
Objective: To investigate the molecular mechanism of the disease based on the clinical characterization and genetic mutation analysis in a family with hereditary spherocytosis. ...
[Genotype and Phenotype of α-Thalassemia Fusion Gene in Huadu District of Guangzhou, Guangdong Province of China] [0.03%]
广东省广州市花都区α-地贫基因及其临床表型分布研究
Ai-Ping Ju,You-Qiong Li,Keng Lin et al.
Ai-Ping Ju et al.
Objective: To explore the carrier rate, genotype and phenotype of α-thalassemia fusion gene in Huadu district of Guangzhou, Guangdong province of China, and provide data reference for the prevention and control of thalas...
[Effect of PKM2 on Osteogenic and Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Myeloma Bone Disease] [0.03%]
[pkm2对多发性骨髓瘤骨病中骨髓间充质干细胞成骨和成脂分化的影响]
Jiang-Hua Ding,Shao-Lin Yang,Shu-Lang Zhu
Jiang-Hua Ding
Objective: To investigate the expression of pyruvate kinase M2 (PKM2) in bone marrow mesenchymal stem cells (BMSCs) in myeloma bone disease (MBD) and its effect on osteogenic and adipogenic differentiation of BMSCs. ...
[Construction of a Prognostic Model of Multiple Myeloma Based on Metabolism-Related Genes] [0.03%]
基于代谢相关基因的多发性骨髓瘤预后模型的建立
Ge-Liang Liu,Xi-Meng Chen,Jun-Dong Zhang et al.
Ge-Liang Liu et al.
Objective: To screen the prognostic biomarkers of metabolic genes in patients with multiple myeloma (MM), and construct a prognostic model of metabolic genes. ...
[Bone Marrow Adipocytes Promote the Survival of Multiple Myeloma Cells and Up-Regulate Their Chemoresistance] [0.03%]
骨髓脂肪细胞促进多发性骨髓瘤细胞的存活并上调其化学耐药性
Xiao-Qian Wei,Yang-Min Zhang,Yu Sun et al.
Xiao-Qian Wei et al.
Objective: To investigate the effect of adipocytes in the bone marrow microenvironment of patients with multiple myeloma (MM) on the pathogenesis of MM. M...
[Analysis of the Prognostic Value and Risk Factors of Early Relapse for Newly Diagnosed Multiple Myeloma Patients in the Era of Novel Agents] [0.03%]
新型治疗药物时代新诊断多发性骨髓瘤患者早期复发的预后价值及危险因素分析
Qi-Hui Li,Yan Liu,Jing Wang et al.
Qi-Hui Li et al.
Objective: To investigate the influece of early relapse in the era of novel drugs on the prognosis of the patients with newly diagnosed multiple myeloma（NDMM） and risk factors, and to provide the basis for the early identif...
[The Efficacy and Safety of Daratumumab-Based Regimen in Treatment of Multiple Myeloma Patients with Renal Impairment] [0.03%]
达托珠单抗治疗肾功能损害多发性骨髓瘤患者的有效性和安全性分析
Ling-Ling Yin,Yang-Ling Shen,Feng-Ling Min et al.
Ling-Ling Yin et al.
Objective: To investigate the efficacy and safety of daratumumab in treatment of multiple myeloma (MM) patients with renal impairment (RI). Methods: ...
[Clinical Features and Prognosis of Patients with Castleman's Disease] [0.03%]
Castleman病患者的临床特点和预后分析
Xiu-Juan Huang,Xin-Lian Zhang,Xiao-Fang Wei et al.
Xiu-Juan Huang et al.
Objective: To analyze the clinical features and prognosis of patients with Castleman's disease (CD) and improve the diagnosis and treatment of CD. Methods...
[Diagnosis Significance of the Levels of Cytokines IL-6, IL-10 and CXCL-13 in Cerebrospinal Fluid for Central Nervous System Infiltration of Lymphoma] [0.03%]
中枢神经系统淋巴瘤浸润脑脊液细胞因子IL-6、IL-10和CXCL-13水平的诊断意义
Li-Xin Liu,Jing-Hua Liu,Ji-Gang Wang et al.
Li-Xin Liu et al.
Objective: To evaluate the diagnostic value of the expression levels of cytokines interleukin-6(IL-6), interleukin-10 (IL-10) and chemokine （C-X-C motif） ligand-13 (CXCL-13) in cerebrospinal fluid (CSF) for central nervous ...
[The In Vivo Intervention and Relative Mechanism of Genistein on the Inflammation and Thrombophilia in Lymphoma-Bearing Mice] [0.03%]
染料木素干预淋巴瘤荷瘤小鼠炎症及促凝机制的体内研究
Zhi-Yue Chen,Qing-Qing Shi,Xin Sun et al.
Zhi-Yue Chen et al.
Objective: To investigate the in vivo intervention and relative mechanism of Genistein (GEN) on tumor-associated inflammatory and tumor thrombophilia in lymphoma-bearing mice. ...