[Bioinformatics screening and analysis of key genes of ferroptosis and autophagy in alcoholic liver disease and their validation] [0.03%]
生物信息学筛选及酒精性肝病铁死亡和自噬关键基因的验证分析
Q Q Zhang,Q Q Zhang,H Y Zhang et al.
Q Q Zhang et al.
Objective: To screen and analyze key genes of ferroptosis and autophagy using bioinformatics and to validate them correspondingly in order to provide a basis for identifying key therapeutic targets for alcoholic liver disease (ALD). Methods...
[Changes in hepatic phase Ⅱ detoxification enzymes and their mechanism in metabolic associated steatohepatitis (MASH) induced by MCD diet in mice] [0.03%]
[MCD饮食诱导的小鼠代谢相关脂肪性肝炎(MASH)模型肝相二期解毒酶变化及其机制]
J Q Gao,B Zuo,C Q Pi et al.
J Q Gao et al.
Objective: To investigate the changes in hepatic phase II detoxification enzymes and their mechanism in metabolic associated steatohepatitis (MASH) induced by a methionine-choline-deficient (MCD) diet in mice. Methods: Ten C57BL/6J mice wer...
[Analysis of the impact of tumor diameter on short-term prognosis in patients with hepatitis B-related hepatocellular carcinoma-inducing acute-on-chronic liver failure] [0.03%]
乙型肝炎相关性肝癌并发亚急性肝功能衰竭短期预后与肿瘤直径的影响分析
Y H Peng,J Chen,C Li et al.
Y H Peng et al.
Objective: To investigate the impact of the size of the liver tumor diameter on the prognosis of patients with hepatitis B-related hepatocellular carcinoma (HCC)-inducing acute-on-chronic liver failure (HBV-HCC/ACLF). Method: A retrospectiv...
[Study on the role and mechanism of quercetin promoting autophagy in HCCLM3 cells via STING signaling] [0.03%]
[山柰酚通过STING信号促进HCCLM3细胞自噬的作用及机制研究]
L Chen,G Z Wu,Y Zhu et al.
L Chen et al.
Objective: To explore the effects of quercetin on autophagy and proliferation in HBV-positive liver cancer HCCLM3 cells based on STING signaling and its underlying mechanism. Methods: HCCLM3 cells were treated with quercetin (50 μmol/L or ...
[Clinical outcomes of small-size grafts in auxiliary liver transplantation for the treatment of portal hypertension] [0.03%]
辅助肝移植减压治疗门静脉高压症的小肝脏效果分析
H F Ju,L Wei,L Y Sun et al.
H F Ju et al.
Objective: To evaluate the safety and efficacy of using small and ultra-small sized grafts for in situ auxiliary liver transplantation in the treatment of portal hypertension. Methods: A prospective single-arm cohort study was conducted. Pa...
[Advantages and challenges of auxiliary liver transplantation therapeutic strategies for patients with acute liver failure] [0.03%]
[急性肝功能衰竭辅助性肝脏移植治疗策略的优缺点及挑战]
L Y Sun,L Wei,W Qu et al.
L Y Sun et al.
The mortality rates are significantly elevated with the rapid progression of acute liver failure in the absence of timely diagnosis and treatment. Liver transplantation is an effective therapeutic approach that can halt disease progression,...
[Advances in minimally invasive surgical techniques for liver transplant recipients] [0.03%]
肝移植受者的微创外科技术进展
Z Feng,X F Zhang,Y Lyu
Z Feng
In recent years, minimally invasive surgical techniques, especially laparoscopic and robot-assisted surgery, have fundamentally changed the standard procedure for living donor liver retrieval and are gradually expanding into the core area o...
[Novel research horizon for liver transplantation management model in hepatocellular carcinoma based on the tumor-donor liver-recipient] [0.03%]
基于肿瘤-供肝-受者的原发性肝癌移植管理模型的新研究视角
S J Xu,Y Y Xu,X Xu
S J Xu
Hepatocellular carcinoma (hereinafter referred to as liver cancer) is the main indication for liver transplantation in China, but postoperative tumor recurrence and metastasis severely restrict the efficacy of liver transplantation. There e...
Q Y Liu,Q Zhao,X S He
Q Y Liu
Liver transplantation is the standard therapy for end-stage liver disease, but the long-standing shortage of donor livers has constrained its advancement. The use of standard donor criteria expansion partially alleviates the supply-demand i...
Z J Zhu
Z J Zhu
Liver transplantation techniques have made significant advances in recent years in surgical procedures, expanding liver donor sources and perioperative management, leading to markedly improved patient survival rates. This review focuses on ...