[Advancement in the role of exosomes for hepatitis B virus infection diagnosis and treatment: mechanisms and clinical applications] [0.03%]
外泌体在乙肝病毒感染诊断及治疗中的作用进展：机制和临床应用
M X Du,W T Hua,S H Wan et al.
M X Du et al.
Hepatitis B virus (HBV) infection is a major global public health problem, causing approximately one million deaths annually. Exosomes are nanosized vesicles (30-150 nm) enclosed in a lipid bilayer membrane, secreted by almost all cells, an...
[Clinical significance and occurrence mechanism of hepatitis B virus DNA integration] [0.03%]
乙肝病毒DNA整合的临床意义及发生机制
Y J Shi,K X Zhang,M Y Li et al.
Y J Shi et al.
Double-stranded linear DNA (dslDNA), considered to serve as a major precursor to integrated HBV DNA (iDNA), is generally located in the livers of patients with chronic HBV infection. Prior research has primarily focused on the role and mech...
[Analysis of the efficacy and survival outcomes of plasma exchange combined with dual plasma molecular adsorption system therapy in liver failure] [0.03%]
血浆置换联合双重血浆分子吸附系统治疗肝衰竭的疗效及生存分析
J J Ding,L Bao,W J Cao et al.
J J Ding et al.
Objective: To investigate the therapeutic effect and prognostic impact of plasma exchange (PE) combined with dual plasma molecular adsorption system (DPMAS) therapy in patients with liver failure (LF). Methods: A retrospective study was con...
[Analysis of the clinical characteristics of 45 cases of autoimmune liver disease in the Xizang population] [0.03%]
西藏地区45例自身免疫性肝病临床特征分析
D J C Sangdan,J Wang
D J C Sangdan
Objective: To explore the clinical, biochemical, immunological, and treatment characteristics of autoimmune liver disease in the Xizang population so as to provide a reference for clinical diagnosis and treatment in this region. Methods: Cl...
[Distribution of serum HBV RNA in the natural history of chronic HBV infection and factors influencing HBV RNA negativity: a retrospective study stratified by HBeAg status] [0.03%]
慢性HBV感染自然史中血清HBV RNA分布及其阴性因素：HBeAg状态分层的回顾性研究
Y J Li,J H Deng,Z L Yan et al.
Y J Li et al.
Objective: To characterize the distribution of serum hepatitis B virus (HBV) RNA in patients with HBV infection according to different HBeAg statuses and natural history stages, to analyze factors associated with HBV RNA negativity, and to ...
[Analysis of the efficacy and safety profile of the use of eltrombopag ethanolamine tablets in patients with cirrhotic thrombocytopenia] [0.03%]
艾曲波帕乙醇胺片治疗肝硬化血小板减少患者的有效性和安全性分析
H B Ning,H M Jin,K Li et al.
H B Ning et al.
Objective: To investigate and analyze the efficacy and safety profile data on the use of eltrombopag drugs in patients with cirrhotic thrombocytopenia scheduled for invasive procedures. Methods: A retrospective analysis was conducted on 51 ...
[APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update] [0.03%]
2026年亚洲太平洋肝脏研究学会慢性乙型肝炎感染管理临床实践指南更新
H You,Rakhi Maiwall,J Chen et al.
H You et al.
Globally, especially in the Asia-Pacific region, chronic hepatitis B infection has led to an undesirable escalating morbidity and mortality with acute-on chronic liver failure, end-staged liver cirrhosis and hepatocellular carcinoma. This h...
[Emphasis on the etiological diagnosis and management of non-cirrhotic portal hypertension] [0.03%]
重视非肝硬化门静脉高压的病因诊断与治疗
J Liu,L L Zhao,J Li
J Liu
Non-cirrhotic portal hypertension (NCPH) refers to portal hypertension that occurs in patients without cirrhosis. Currently, the diagnosis rate is gradually increasing, but the existing etiologies are highly heterogeneous and are not yet fu...
L H Zheng,X M Zhou
L H Zheng
Cirrhosis can cause elevated portal vein pressure and the opening of collateral circulation, leading to portal hypertension. Esophagogastric variceal rupture and bleeding are the most urgent clinical manifestations of cirrhotic portal hyper...
[Novel targets and drugs for the treatment of portal hypertension in liver cirrhosis] [0.03%]
肝硬化门脉高压治疗的新靶点和药物
C P Zhu,W F Xie
C P Zhu
Portal hypertension in liver cirrhosis is a key factor driving decompensation and mortality, and pharmacological therapy has been the cornerstone of treatment. Although traditional medications, mainly non-selective β-receptor blockers, hav...