[Research advances of magnetic resonance elastography for assessing the bioinvasiveness in hepatocellular carcinoma] [0.03%]
[磁共振弹性成像评估肝细胞癌生物侵袭性的研究进展]
M Y Ma,R K Li
M Y Ma
The invasiveness of hepatocellular carcinoma (HCC) is closely correlated with the dynamic changes in the biomechanical microenvironment. The solid (e.g., tissue sclerosis due to stromal fibrosis) and fluid mechanics processes (e.g., disorde...
[Global differences and challenges in the definition of acute liver failure] [0.03%]
[急性肝功能衰竭定义的全球差异及挑战]
Y Ren,M Kong,M M Xu et al.
Y Ren et al.
Acute liver failure (ALF) is a critical syndrome characterized by sudden deterioration of liver function, coagulopathy, and hepatic encephalopathy, with a very high mortality rate. However, the global ALF diagnostic criteria exhibit signifi...
[A real-world study of clinical cure in children with HBeAg-positive chronic hepatitis B from the Guangxi region] [0.03%]
[广西地区HBsAg、HBeAg阳性和HBsAg阳性、HBeAg阴性慢性乙型肝炎患儿的临床治愈研究]
R Y Lyu,J H Tian,S M Huang et al.
R Y Lyu et al.
[Clinical characteristics and follow-up in children with Alagille syndrome] [0.03%]
儿童Alagille综合征的临床特征及随访结果分析
W W Liu,X M Zhong,P Wang et al.
W W Liu et al.
Objective: To investigate the clinical and genetic features and follow-up outcomes in children with Alagille syndrome (ALGS). Methods: A retrospective cohort study was conducted. Clinical data from 24 children diagnosed with ALGS treated at...
[Exploring the protective effects and mechanisms of HYX1-derived exosomes on acute liver failure based on disulfidptosis signaling] [0.03%]
基于二硫键分解信号的HYX1来源外泌体对急性肝衰竭保护作用及机制探索
Q Yang,H X Tang,X X Liu et al.
Q Yang et al.
Objective: To explore the protective effect and molecular mechanism of human liver stem cell line HYX1-derived exosomes (HYX1-Exos) on acute liver failure (ALF) based on disulfidptosis signaling. Methods: Healthy male BALB/c mice were intra...
[Study on the establishment, assessment, and drug sensitivity testing for intrahepatic cholangiocarcinoma organoid models based on the suspension culture method] [0.03%]
基于悬浮培养法的肝内胆管癌类器官模型的建立、鉴定及药敏检测研究
Y H Su,W Huang,C Yu et al.
Y H Su et al.
Objective: To investigate the feasibility of establishing intrahepatic cholangiocarcinoma (ICC) organoid models based on the suspension culture method. Methods: Fresh tumor tissue specimens were prepared from six patients with intrahepatic ...
[Diagnostic value and clinical significance of matrix metalloproteinase-7, gamma-glutamate transferase, and liver stiffness measurement with ultrasound elastography in children with biliary atresia] [0.03%]
金属基质素酶-7、γ-谷氨酰转移酶及超声 elastography 评估肝硬度检测在胆道闭锁患儿中的诊断价值及临床意义
J M Zhang,Y L Sun,Q Z Li et al.
J M Zhang et al.
Objective: To investigate the diagnostic value and clinical significance of matrix metalloproteinase-7 (MMP-7), gamma-glutamyl transferase (GGT), and liver stiffness measurement (LSM) with ultrasound elastography in children with biliary at...
[ATPase H+ transporter expression with prognosis in hepatocellular carcinoma] [0.03%]
肝细胞癌中ATP酶H+转运体的表达与预后关系的研究
Q Yuan,Y Q Jin,Y X Cao et al.
Q Yuan et al.
Objective: To investigate the expression level of ATPase H+ transporting accessory protein 1 (ATP6AP1) in hepatocellular carcinoma (HCC) lines and its effect on cell proliferation and migration, providing a new target for the treatment of H...
[Interferon-α induces disulfidptosis occurrence in human liver cancer cells] [0.03%]
干扰素诱导人肝癌细胞中二硫键介导的蛋白质降解发生
X Y Bi,J Zhang,L H Xu et al.
X Y Bi et al.
Objective: To investigate the potential molecular regulatory mechanism of interferon-α (IFN-α)-induced disulfidptosis occurrence in human liver cancer cells. Methods: Glucose starvation and IFN-α treatment models were constructed using h...
[Precise clinical classification of metabolic associated fatty liver disease] [0.03%]
[代谢相关脂肪性肝病的精准临床分类]
W R Su,J J Ding,Q Pan et al.
W R Su et al.
Metabolic associated fatty liver disease (MAFLD) is the most common chronic liver disease worldwide, and its significant clinical and pathophysiological heterogeneity poses a serious challenge to traditional "one-size-fits-all" diagnostic a...