[Multi-functional drive to build a first-class platforms for academic exchange] [0.03%]
[多功能驱动打造一流学术交流平台]
A L Huang,H Ren,X Y Xu
A L Huang
Q Jiang,Y S Su,X Y Cao et al.
Q Jiang et al.
Liver failure is severe liver damage caused by multiple factors, with a very high mortality rate. Artificial liver support systems have become a core strategy for alternative or bridging therapy in the context of the rapid progression of li...
[Research progress on serum chitinase-3-like protein 1 for diagnosing early-stage liver fibrosis non-invasively] [0.03%]
血清糖萼三糖蛋白1无创诊断早期肝纤维化的研究进展
X N Li,B Wang
X N Li
Liver fibrosis is a pathological change caused by hepatocyte inflammation and necrosis due to various etiologies, leading to excessive deposition of the extracellular matrix. Furthermore, it can progress to liver cirrhosis or even cancer if...
[Research progress on animal models relevant to porto-sinusoidal vascular disease] [0.03%]
与porto-窦性血管病相关的动物模型研究进展
M Li,J Z Wang,C H Liu
M Li
In recent years, the European Society for Vascular Surgery has proposed the concept of porto-sinusoidal vascular disease (PSVD) based on idiopathic non-cirrhotic portal hypertension (INCPH), thereby expanding the scope of these disease cond...
[Clinical research advances for small-molecule nucleic acid drugs in the treatment of chronic hepatitis B] [0.03%]
小分子核酸药物治疗慢性乙型肝炎研究进展
W X Wang,Y M Guo,Z X Fei et al.
W X Wang et al.
Currently, the commonly used antiviral drugs for hepatitis B virus (HBV) primarily include nucleos(t)ide analogues and interferons, which effectively suppress viral replication but typically have difficulty achieving clinical cure of chroni...
[Role of Kupffer cells in liver regeneration with metabolic associated fatty liver disease in mice] [0.03%]
代谢相关脂肪性肝病小鼠再生肝脏中枯氏细胞的作用研究
T W Wang,L Liu,S Y Wang et al.
T W Wang et al.
Objective: To investigate the effect of Kupffer cells on liver regeneration with metabolic associated fatty liver disease (MAFLD) induced by a methionine-choline-deficient (MCD) diet in mice. Methods: Eight-week-old C57BL/6J male mice were ...
[Evaluation of the efficacy of the Baveno VI criteria in diagnosing clinically significant portal hypertension under different etiologic control statuses] [0.03%]
[巴维诺六条标准诊断不同病因控制水平下显著门脉高压疗效评价]
S Y Fang,H Li,X Cheng et al.
S Y Fang et al.
Objective: To evaluate the efficacy of the Baveno VI criteria in the diagnosis of clinically significant portal hypertension (CSPH) under two conditions: non-etiological control and complete etiological control. Methods: A cross-sectional s...
[Analysis of serum lipidomics for a spontaneous hepatic fibrosis mouse model] [0.03%]
自发性肝纤维化小鼠模型的血清脂质组学分析
J H Zheng,K Wu,K Wang et al.
J H Zheng et al.
Objective: To construct Slc27a5 gene knockout mice and investigate changed conditions in the serum lipidomics. Methods: Liver tissues and serum samples were collected from wild-type and Slc27a5 gene knockout mice at different time points. H...
[Analysis of a study for the global trend burden of MAFLD-associated cirrhosis based on the 2024 update of the Global Burden of Disease Database] [0.03%]
基于2024年全球疾病负担数据库更新的MAFLD相关肝硬化的全球疾病负担研究分析
N He,F N Zhang,R X Li et al.
N He et al.
Objective: This study systematically assessed the latest epidemiological model and changing trends of metabolic-associated fatty liver disease (MAFLD)-associated cirrhosis at the global and regional levels based on the updated 2021 Global B...