[Excerpt from the 2025 EASL practice guidelines for the diagnosis and treatment of extrahepatic cholangiocarcinoma] [0.03%]
2025年EASL胆管癌诊断和治疗实践指南摘译
Y W Shang,G H Han
Y W Shang
In recent years, significant progress has been made in the imaging, molecular characterization, and systemic treatment of extrahepatic cholangiocarcinoma (CCA). However, early-stage detection, accurate classification, and effective manageme...
[Expert recommendations on the management of adverse reactions in pegylated interferon alpha therapy for chronic hepatitis B] [0.03%]
[聚乙二醇化干扰素α治疗慢性乙肝不良反应管理专家建议]
Expert Group on the Management of Adverse Reactions in Pegylated Interferon Alpha Therapy for Chronic Hepatitis B
Expert Group on the Management of Adverse Reactions in Pegylated Interferon Alpha Therapy for Chronic Hepatitis B
To provide a usage reference for clinicians with the increasing use of pegylated interferon alpha (PEG-IFN-ɑ) in treating chronic hepatitis B (CHB), the expert panel retrospectively summarized previous clinical experience and formulated ex...
[Expert consensus on the clinical diagnosis and treatment of coagulation disorders related to liver disease] [0.03%]
肝病相关凝血障碍临床诊断与治疗专家共识
National Clinical Research Center for Infectious Diseases;Society of Hepatology;Beijing Medical Association;Translational Medicine Branch, Chinese Association of Gerontology and Geria
National Clinical Research Center for Infectious Diseases;Society of Hepatology;Beijing Medical Association;Translational Medicine Branch
Coagulation disorders are a major contributing factor to bleeding and thrombotic diseases in patients with liver disease. Furthermore, it is one of the severe complications, which is closely related to disease progression and poor prognosis...
[Key epidemiological data and recommended prevention and control measures for primary liver cancer] [0.03%]
[肝癌流行病学主要数据及防控建议]
G W Cao
G W Cao
Primary liver cancer (PLC) accounted for 865,000 new cases worldwide in 2022, ranking sixth among all malignant tumors in terms of incidence, and 758,000 deaths, ranking third in mortality. The age-standardized 5-year survival rate for PLC ...
[Research advances on hepatocyte zonal changes in metabolic associated fatty liver disease] [0.03%]
代谢相关脂肪性肝病下肝细胞区室化变化的研究进展
Y Li,Z W Huang,J T Gan et al.
Y Li et al.
Hepatocyte zonation is a core feature of the spatial heterogeneity of liver function, which is driven by the process of gradients of oxygen and nutrients from the portal vein to the central vein and is precisely regulated by signaling pathw...
[Research progress on poor response, resistance mechanisms, and influencing factors of immunotherapy for hepatocellular carcinoma] [0.03%]
肝癌免疫治疗低反应、耐药机制及影响因素研究进展
M Huang,F N Zhang,H Gong et al.
M Huang et al.
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Although immune checkpoint inhibitors offer hope for patients with advanced- stage HCC, the objective response rate remains only 15% to 30%, mai...
[Advances in the application of exhaled breath analysis technology in the detection and diagnosis of liver failure] [0.03%]
呼出气分析技术在肝衰竭检测与诊断中的应用进展
S T Zhang,Y S Liu,Y L He
S T Zhang
In recent years, exhaled breath analysis technology has shown significant potential for the detection and diagnosis of liver diseases as an innovative noninvasive diagnostic method. This paper systematically reviews the recent relevant lite...
[Research progress on the effects of time-restricted eating on metabolic associated fatty liver disease] [0.03%]
限时饮食对代谢相关性脂肪肝病影响的研究进展
Z Q Jiang,T J Wei,G X Li
Z Q Jiang
Metabolic-associated fatty liver disease (MAFLD) is a common chronic liver disease closely related to metabolic disorders. Currently, the effective pharmacological treatments are scarce. In recent years, time-restricted eating (TRE), as an ...
[Research advances of magnetic resonance elastography for assessing the bioinvasiveness in hepatocellular carcinoma] [0.03%]
[磁共振弹性成像评估肝细胞癌生物侵袭性的研究进展]
M Y Ma,R K Li
M Y Ma
The invasiveness of hepatocellular carcinoma (HCC) is closely correlated with the dynamic changes in the biomechanical microenvironment. The solid (e.g., tissue sclerosis due to stromal fibrosis) and fluid mechanics processes (e.g., disorde...
[Global differences and challenges in the definition of acute liver failure] [0.03%]
[急性肝功能衰竭定义的全球差异及挑战]
Y Ren,M Kong,M M Xu et al.
Y Ren et al.
Acute liver failure (ALF) is a critical syndrome characterized by sudden deterioration of liver function, coagulopathy, and hepatic encephalopathy, with a very high mortality rate. However, the global ALF diagnostic criteria exhibit signifi...