S Tang,W Hou,Z P Duan et al.
S Tang et al.
Hepatolenticular degeneration, also known as Wilson disease (WD), is a type of copper metabolism disorder caused by an ATP7B gene variant, which is manifested by the abnormal accumulation of copper in the liver and other organs, resulting i...
H Jiang,C Liang,H Liu et al.
H Jiang et al.
Copper, as a kind of trace element, is crucial for the physiological functions of various key enzymes in the body, and the liver plays a central role in maintaining copper metabolism. Theoretically, dysfunction in the body's metabolic proce...
[Analysis and comparison of bile acid metabolism characteristics in children and adults with metabolic- associated fatty liver disease] [0.03%]
[儿童和成人代谢相关性脂肪肝病胆汁酸代谢特征的分析与比较]
C H Yang,N Mei,Y Wang et al.
C H Yang et al.
Metabolic-associated fatty liver disease has become a common chronic liver disease with changes in lifestyle and the increasing prevalence rate of overweight and obesity in adults and even children. The liver synthesizes bile acids via chol...
[Research progress on the impact of metabolic associated fatty liver disease on viral activity, treatment response, and prognosis in patients with chronic hepatitis B: current status and prospects] [0.03%]
代谢相关脂肪性肝病对慢性乙型肝炎患者病毒活性、治疗反应及预后影响的研究进展：现状与前景
H Gong,T T Zhao,M Huang et al.
H Gong et al.
Chronic hepatitis B (CHB) can gradually progress to life-threatening diseases such as cirrhosis and hepatocellular carcinoma (HCC). In recent years, with the change in people's lifestyles, the incidence rate of metabolic associated fatty li...
[CENPI promotes the migration of liver cancer cells and the epithelial-mesenchymal transition process by activating the RAS/MEK/ERK signaling axis] [0.03%]
CENPI通过激活RAS/MEK/ERK信号轴促进肝癌细胞迁移及上皮间质转化效应
S S Lu,W Huang,S J Ge et al.
S S Lu et al.
Objective: To detect the expression level and clinical significance of centromere protein I (CENPI) in hepatocellular carcinoma (HCC) and to preliminarily explore the effects of CENPI on the biological behavior of liver cancer cells and its...
[Construction of a machine learning prognostic prediction model based on psoas muscle index for patients with decompensated liver cirrhosis] [0.03%]
基于腰大肌指数的机器学习模型在肝硬化失代偿期患者预后预测中的构建及验证
M Y Luo,D Yan,X Wang et al.
M Y Luo et al.
Objective: To explore the effect of psoas muscle index (PMI) and construct a machine learning model to validate the 180-day prognosis in patients with decompensated liver cirrhosis. Methods: Retrospective data were collected from patients w...
[Analysis of liver histological characteristics and clinically related factors in patients with inactive HBsAg carriers] [0.03%]
HBsAg阴性慢性乙型肝炎患者肝脏组织学特征及临床相关因素分析
X Y Zhang,S Ren,S J Zheng et al.
X Y Zhang et al.
Objective: To analyze the liver histological characteristics and clinically related factors in inactive hepatitis B surface antigen (HBsAg) carriers (IHC), and also explore whether antiviral treatment is necessary for IHC, as defined in the...
[Predictive value of neutrophil/lymphocyte ratio in the prognosis of primary biliary cholangitis] [0.03%]
中性粒细胞与淋巴细胞比值对原发性胆汁性胆管炎预后预测价值的研究
H L Zhu,M Y Zheng,W B Li et al.
H L Zhu et al.
Objective: To predict pre-treatment clinical parameters that are associated with poor response and prognosis to ursodeoxycholic acid (UDCA) in patients with primary biliary cholangitis (PBC) and to use second-line treatment drugs in the ear...
[Analysis of clinical characteristics and current diagnosis and treatment status of IgG4-related diseases in the real world] [0.03%]
我国IgG4相关疾病诊疗现状调查及临床特征分析
X F Wang,L N Cui,G Jia et al.
X F Wang et al.
Objective: To retrospectively analyze the current status of consultation, clinical characteristics, and treatment status of patients with IgG4-related disease (IgG4-RD) in order to provide assistance and a basis for early and standardized d...
[Clinical characteristics and risk factors for disease progression in patients with anti-gp210 antibody-positive primary biliary cholangitis] [0.03%]
抗gp210抗体阳性原发性胆汁性肝硬化患者的临床特征及影响预后的危险因素分析
Y Ran,X Y Wang,Z Yang et al.
Y Ran et al.
Objective: To explore the clinical characteristics and identification of the independent risk factors for disease progression in patients with anti-gp210 antibody-positive primary biliary cholangitis (PBC). Methods: A retrospective cohort s...