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Wen-Zhe Li,Huan Wang,Meng-Meng Wang et al.
Wen-Zhe Li et al.
Target trial emulation(TTE) has emerged in recent years as a key framework for causal inference, providing a methodological foundation for generating evidence with higher quality by using real-world data in situations where conducting a ran...
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糖尿病周围神经病变中医证型分布规律及临床特征分析
Jia-Jie Li,Jin-Xing Liu,Jin-Chen Guo et al.
Jia-Jie Li et al.
Using multiple statistical methods, this study investigated the core diagnostic information from the four diagnostic methods, the distribution patterns of syndrome elements, and their relationship with laboratory biochemical indicators in d...
[Evidence mapping analysis of clinical research on TCM for chronic obstructive pulmonary disease in recent five years] [0.03%]
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Jia-Lin Pan,Ying-Zi Tian,Yu-Jin Ding et al.
Jia-Lin Pan et al.
This study employed evidence mapping to systematically summarize clinical research on TCM for treating chronic obstructive pulmonary disease(COPD) in recent five years, aiming to characterize the distribution characteristics and methodologi...
[Compound Ciwujia Granules for chronic fatigue syndrome with syndrome of deficiency of both heart and spleen: a multicenter, randomized, double-blind, double-dummy, positive drug-controlled trial] [0.03%]
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Jun Ren,Xiao-Tian Zhang,Chao-Qun Xie et al.
Jun Ren et al.
This study aimed to evaluate the clinical efficacy and safety of Compound Ciwujia Granules in patients with chronic fatigue syndrome with syndrome of deficiency of both heart and spleen. It adopted a multicenter, double-blind, double-dummy,...
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Qi-Ran Chen,Fu-Kang Jia,Jian-Hui Feng et al.
Qi-Ran Chen et al.
A total of 9 constituents(catalpol, rehmannioside A, rehmannioside D, ajugol, aucubin, regaloside A, regaloside B, regaloside C, and regaloside E) from Baihe Dihuang Decoction in the plasma samples of normal and depression rats were simulta...
[Study on mechanism of Zhenwu Decoction against heart-kidney Yang deficiency-induced heart failure via cAMP/PKA signaling pathway] [0.03%]
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Ya-Shu Li,Jing Zhao,Jian-Bei Li et al.
Ya-Shu Li et al.
This study aimed to investigate the effects of Zhenwu Decoction(ZWT) on cardiac fibrosis in mice with heart-kidney Yang deficiency-induced chronic heart failure(CHF). The research further explored the therapeutic mechanisms of ZWT in CHF tr...
[Mechanism of Xiaoyao San in ameliorating of brain-gut interaction disorder in chronic stress mice based on Th1/Th2 immune balance] [0.03%]
小柴胡汤通过调节慢性应激小鼠Th1/Th2免疫平衡改善脑-肠轴紊乱的作用机制研究
Shu-Ya Wu,Bei-Bei Dong,Qian-Yin Xue et al.
Shu-Ya Wu et al.
This study investigated the mechanism by which Xiaoyao San ameliorates "brain-gut" interaction disorders in chronic stress-induced mice by examining its effects on T helper 1 cell(Th1)/T helper 2 cell(Th2) immune balance. Forty male C57BL/6...
[Improving effect and mechanism of Bugan Decoction on sperm quality in mice with exercise-induced fatigue via PARP-1] [0.03%]
补肾固精方改善运动疲劳小鼠精子质量及PARP-1机制研究
Xin Hu,Min Xiao,Xiao-Cui Jiang et al.
Xin Hu et al.
This study aimed to investigate the effect and mechanism of Bugan Decoction on spermatogenesis in mice with exercise-induced fatigue. Male ICR mice were screened by swimming training and randomly divided into seven groups(n=10 per group): a...
[Mechanism of total flavonoids from Smilacis Glabrae Rhizoma against obesity-associated colorectal cancer via regulation of fatty acid oxidation] [0.03%]
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Jian-Qin Xu,Zhao-Wei Cai,Zi-Yao Pang et al.
Jian-Qin Xu et al.
This study aimed to investigate the mechanism of total flavonoids from Smilacis Glabrae Rhizoma(SGF) against obesity-associated colorectal cancer(CRC) via regulation of fatty acid oxidation(FAO). In vivo, syngeneic subcutaneous and orthotop...
[Study on Huanglian Jiedu Decoction improving ox-LDL-induced LC3-related phagocytosis dysfunction in RAW264.7 macrophages by activating ERK5] [0.03%]
黄连解毒汤改善氧化低密度脂蛋白诱导的RAW264.7巨噬细胞LC3相关吞噬作用功能障碍的机制研究
Song-Fan Wang,Ying-Yi Jiang,Xing-Yuan Li et al.
Song-Fan Wang et al.
To investigate whether the anti-atherosclerotic(AS) effect of Huanglian Jiedu Decoction(HLJDD) is associated with activation of extracellular signal-regulated kinase 5(ERK5) and the consequent improvement of microtubule-associated protein 1...