[Safety grading of Chinese patent medicines (including injections) during pregnancy] [0.03%]
妊娠期常用中成药(含注射剂)安全性分级
Zhi-Rong Gu,Hong-Ning Chen,Qian Qian et al.
Zhi-Rong Gu et al.
At present, China has no autonomous safety classification for medication use during pregnancy, and there is even no safety classification or related information for Chinese patent medicines(including injections) used during pregnancy, leavi...
[UHPLC-Orbitrap-MS and targeted metabolomics reveal chemical distribution characteristics and main chemical content of Tibetan medicine Liuwei Muxiang Pills] [0.03%]
[UHPLC-Orbitrap-MS和靶向代谢组学揭示六味木香丸的化学分布特征及主要成分含量]
Jie-Ji Duo,Dong-Zhi Luosang,Chun-Yu Wang et al.
Jie-Ji Duo et al.
This study aims to identify the main chemical components of the Tibetan medicine Liuwei Muxiang Pills(LWMXP) by using mass spectrometry and targeted metabolomics, analyze the distribution characteristics of its main components in the serum ...
[Evidence mapping analysis of clinical research on TCM for diabetic kidney disease in recent six years] [0.03%]
基于近六年来糖尿病肾脏疾病中医药临床研究的证据图谱分析
Ran Li,Peng-Tao Dong,Ya-Bin Gao et al.
Ran Li et al.
The study employed an evidence mapping approach to systematically review clinical research on TCM for diabetic kidney disease(DKD) over the past six years and evaluate the current state of evidence, aiming to provide a scientific basis and ...
[Analysis of association between HIF-1α gene polymorphism and different syndromes of early cough variant asthma patients and their lung function] [0.03%]
[HIF-1α基因多态性与早发咳嗽变异性哮喘不同证候的相关性分析及对肺功能的影响]
Qing Xu,Yin Gao,Li-Hong Zhang et al.
Qing Xu et al.
This study aims to explore the association between the polymorphism of HIF-1α gene and the susceptibility to early cough variant asthma(CVA) with Qi deficiency and blood stasis, lung and spleen Qi deficiency, liver fire invading lung, and ...
[Clinical study of Total Glucosides of Paeony Capsules for oral lichen planus with Yin-deficiency and internal-heat pattern: efficacy evaluation and analysis of tongue and pulse characteristics] [0.03%]
口服雷公藤多苷片联合养阴清热颗粒治疗阴虚内热证口腔扁平苔藓临床研究:有效性评价及舌脉特征分析
Zhi-Hui Zhang,Li-Yuan Tao,Yan Zhang et al.
Zhi-Hui Zhang et al.
Oral lichen planus(OLP) is a chronic inflammatory oral mucosal disease with potential malignant transformation risk. Yin-deficiency and internal-heat is a common TCM subtype characterized by a red tongue with thin white coating and a thin a...
[Elucidation of pharmacodynamic material basis and in vivo metabolites of Longqing Capsules using UPLC-Q-Exactive-Orbitrap-MS technique] [0.03%]
基于UPLC-Q-Exactive-Orbitrap-MS技术的龙晴胶囊药效物质基础及体内代谢产物阐明
Mi-Chan Zhang,Yu-Fei Lei,Jun Wu et al.
Mi-Chan Zhang et al.
The UPLC-Q-Exactive-Orbitrap-MS technique was employed to investigate the pharmacodynamic material basis of Longqing Capsules and their metabolites in rats, as well as to infer potential metabolic pathways. The contents of Longqing Capsules...
[Study on mechanism of Jiedu Huxin Formula protecting against heart failure caused by hypertension by regulating TGF-β1/p38 MAPK/NF-κB pathway based on network pharmacology and experimental validation] [0.03%]
基于网络药理学和实验验证的解毒护心方通过调控TGF-β1/p38 MAPK/NF-κB信号通路保护高血压心脏病的作用机制研究
Jia-le He,Jiang-Lin Xu,Jian-Wei Yue et al.
Jia-le He et al.
Using data mining methods, this study analyzed and summarized the medication patterns and detoxification therapies employed in TCM for treating heart failure caused by hypertension(hypertensive heart failure). It optimized the detoxifying h...
[Mechanism study on regulation of maternal-fetal immune balance in treatment of recurrent spontaneous abortion by Wenyang Jianpi Formula targeting CREB/TLRs/Th17/Treg axis] [0.03%]
温阳健脾方调控母胎免疫失衡治疗复发性流产的机制研究CREB/TLRs/Th17/Treg轴方向
Li Ji,Qian-Qian Wan,Gui-Shuang Zhao et al.
Li Ji et al.
This study aims to investigate the molecular targets of the Wenyang Jianpi Formula in treating recurrent spontaneous abortion(RSA) and its regulatory mechanisms on maternal-fetal immune balance. An RSA model was established using CBA/J×DBA...
[Effect of Viola tianshanica extract on innate immune response in mice infected with influenza A virus based on RIG-Ⅰ/NLRP3 signaling pathway] [0.03%]
牻牛儿苗提取物通过RIG-I/NLRP3信号通路影响甲型流感病毒小鼠感染的天然免疫反应的作用研究
Yan Liu,Fu-Xiang Luo,Xue Wang
Yan Liu
This study aims to investigate the effect of Viola tianshanica Maxim. extract(VTME) on the innate immune response in mice infected with influenza A virus. Mice were randomly divided into a control group, a virus-infected group, an oseltamiv...
[Study on mechanism of Danzha Tongmai Pills against atherosclerosis based on theory of "phlegm-stasis intermingling"] [0.03%]
基于“痰瘀互结”理论的丹扎通脉丸抗动脉粥样硬化机制研究
Ye-Qin Tao,Hui Liu,Ming-Guo Gao et al.
Ye-Qin Tao et al.
Based on the TCM theory of "phlegm-stasis intermingling", this study aims to investigate the mechanism of Danzha Tongmai Pills(DZTMW) in treating atherosclerosis(AS), focusing on elucidating its in vivo active components, metabolic regulato...