Rofecoxib-Induced Deleterious Effects Escape Detection by Organismal Performance Assays [0.03%]
罗非昔布引起的不良反应逃避了器官功能检测试验的检出
Shannon M Gaukler,James S Ruff,Linda C Morrison et al.
Shannon M Gaukler et al.
Background: Organismal Performance Assays (OPAs) are a unique toxicity quantification method used to assess the safety of potentially toxic compounds, such as pharmaceuticals. OPAs utilize genetically diverse wild mice (M...