Modulation of the p-glycoproein-mediated intestinal secretion of glibenclamide: in vitro and in vivo assessments [0.03%]
格列本脲P-糖蛋白介导的肠道分泌作用的调节：体外和体内评估
P Srirangam,Sagar J Vidya
P Srirangam
The everted gut sac method was used to assess the role of the P-glycoprotein (P-gp) on the intestinal secretion of glibenclamide, a prototype of drug used to treat diabetic mellitus. The study included the evaluation of a P-gp modulator car...
In vitro Effects of Albendazole on Raillietina echinobothrida, the Cestode of Chicken, Gallus domesticus [0.03%]
阿苯达唑对鸡球腺囊尾蚴的体外作用研究
K Lalchhandama
K Lalchhandama
Albendazole, a member of benzimidazole group of compounds, has been shown to have a broad spectrum activity against all classes of helminth parasites. Although it has also been experimentally proven to be effective against cestode infection...
Antiulcer and Anti-inflammatory Activity of Aerial Parts Enicostemma littorale Blume [0.03%]
Enicostemma littoraleBlume地上部分的抗溃疡和抗炎作用
Sp Roy,Cm Niranjan,Tm Jyothi et al.
Sp Roy et al.
The antiulcer and in vitro anti-inflammatory activities of the aerial parts of Enicostemma littorale against aspirin, ethanol, and pyloric ligation-induced ulcers in rats and bovine serum albumin denaturation were studied. The extract (200 ...
Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract [0.03%]
黄瓜果提取物的自由基清除和镇痛作用
D Kumar,S Kumar,J Singh et al.
D Kumar et al.
The aqueous fruit extract of Cucumis sativus L. was screened for free radical scavenging and analgesic activities. The extract was subjected to in vitro antioxidant studies at 250 and 500 μg/ml and analgesic study at the doses 250 and 500 ...
Enhancement of the Norfloxacin Antibiotic Activity by Gaseous Contact with the Essential Oil of Croton zehntneri [0.03%]
Norfloxacin抗生素活性的气体增强作用：库特松油作为抗菌增效剂的研究
Hdm Coutinho,Eff Matias,Kka Santos et al.
Hdm Coutinho et al.
This is the first on the modulation of norfloxacin antibiotic activity by the volatile compounds of an essential oil. We report the chemical composition and antibiotic modifying activity of the essential oil extracted from the leaves of Cro...
Preparation and Evaluation of Nano-vesicles of Brimonidine Tartrate as an Ocular Drug Delivery System [0.03%]
作为眼部药物输送系统的溴莫尼定酒石酸盐纳米囊泡的制备与评估
P Prabhu,Kumar R Nitish,M Koland et al.
P Prabhu et al.
The objective of the present investigation was to design a vesicular formulation of brimonidine tartrate and evaluate its ability to reduce the dosing frequency and improve the therapeutic efficacy of the drug. Nano-vesicles of brimonidine ...
Hari Bn Vedha,Reddy A Brahma,Rani B Samyuktha
Hari Bn Vedha
A multiple-unit floating drug delivery system based on gas formation technique was developed, in order to prolong the gastric residence time and to increase the overall bioavailability of the dosage form. The floating bead formulations were...
Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique [0.03%]
一种雷尼替丁氯化钠缓释制剂的开发及其统计学优化技术研究
S Jain,Ms Srinath,C Narendra et al.
S Jain et al.
The objective of this study was to evaluate the effect of formulation variables on the release properties, floating lag time, and hardness, when developing floating tablets of Ranitidine hydrochloride, by the statistical optimization techni...
Uncovering negative results: introducing an open access journal "journal of pharmaceutical negative results" [0.03%]
揭秘阴性结果：“制药领域阴性结果杂志”创刊
Vipra Kundoor,Ahmed Kk Mueen
Vipra Kundoor
R Jain,S Kosta,A Tiwari
R Jain