An insight into pluripotency and cellular aging through glycan analysis [0.03%]
通过糖类分析探讨多能性与细胞衰老的新视野
Hirabayashi Jun
Hirabayashi Jun
All kinds of cells from all kinds of organisms (i.e., animals, plants, fungi and bacteria) are covered by a dense layer of glycans. The origin of glycans or carbohydrates is not known[1], however, the above fact implies that they are widely...
Mitochondrial distribution violation and nuclear indentations in neurons differentiated from iPSCs of Huntington's disease patients [0.03%]
亨廷顿舞蹈病患者iPSC分化的神经元中线粒体分布异常及核凹陷现象
Evgeny D Nekrasov,Sergey L Kiselev
Evgeny D Nekrasov
AIM: Huntington's disease (HD) is an inherited disease caused by an expansion of cytosine-adenine-guanine (CAG) repeats in the huntingtin gene (HTT) that ultimately leads to neurodegeneration. To study the molecular basis of this disease, i...
Intra-arterial Transplantation of Human Umbilical Cord Blood Mononuclear Cells in Sub-acute Ischemic Stroke Increases VEGF Expression in Rats [0.03%]
人脐带血单个核细胞动脉内移植治疗亚急性脑梗死可增加大鼠VEGF表达
Yetty Ramli,Ahmad Sulaiman Alwahdy,Mohammad Kurniawan et al.
Yetty Ramli et al.
Thrombolysis (rt-PA) is the only United States Food and Drug Administration (FDA) approved drug currently available. Unfortunately, its effect has been limited by the narrow therapeutic time window. Human cord blood mononuclear cells (cbMNC...
Bone Marrow-derived Osteoblasts in the Management of Ovariectomy induced Osteoporosis in Rats [0.03%]
骨髓来源的成骨细胞在治疗卵巢切除诱导的实验性大鼠骨质疏松症中的应用研究
Mir Sadat-Ali,Haifa A Al-Turki,Sadananda Acharya et al.
Mir Sadat-Ali et al.
Background: The objective of this study is to assess if infusion of osteoblasts can temporarily reverse osteoporosis in rats. Methods: Osteoporosis was induced in 20 female Sprague-Dawley rats by performing ovariectomy (OVX) that was carrie...
Granulation tissue-derived mesenchymal stromal cells: a potential application for burn wound healing in pediatric patients [0.03%]
来源于肉芽组织的间充质基质细胞在儿童烧伤创面修复中的应用前景研究
Gloria Pelizzo,Maria Antonietta Avanzini,Melissa Mantelli et al.
Gloria Pelizzo et al.
Objective: Multipotential cells are mobilized into peripheral blood in response to trauma, in particular in severe burns. These cells migrate to the site of injury in response to chemotactic signals to modulate inflammation, repair damaged ...
Proliferation, migration and differentiation potential of human mesenchymal progenitor cells derived from osteoarthritic subchondral cancellous bone [0.03%]
取自骨关节炎松质骨的间充质前体细胞的增殖、迁移及分化潜能
Jan Philipp Krüger,Andreas Enz,Sylvia Hondke et al.
Jan Philipp Krüger et al.
Background: For regenerative therapies in the orthopedic field, one prerequisite for therapeutic success in the treatment of cartilage defects is the potential of body's own cells to migrate, proliferate and differentiate into functional ce...
Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors [0.03%]
通过非病毒表达谱系因子从成人人体细胞衍生的诱导神经前体生成多巴胺神经元样细胞
Rebecca Playne,Kathryn Jones,Bronwen Connor
Rebecca Playne
Reprogramming technology holds great promise for the study and treatment of Parkinson's disease (PD) as patient-specific ventral midbrain dopamine (vmDA) neurons can be generated. This should facilitate the investigation of early changes oc...
Cardiomyogenic Heterogeneity of Clonal Subpopulations of Human Bone Marrow Mesenchymal Stem Cells [0.03%]
人骨髓间充质干细胞克隆亚群的心肌细胞分化差异性研究
Naresh Kumar Tripathy,Syed Husain Mustafa Rizvi,Saurabh Pratap Singh et al.
Naresh Kumar Tripathy et al.
We have evaluated the cardiomyogenic potential of clonal populations of human bone marrow mesenchymal stem cells (BM-MSC). Four rapidly proliferating clones of BM-MSC were obtained from the BM of a healthy donor which were then treated with...