Mitochondrial distribution violation and nuclear indentations in neurons differentiated from iPSCs of Huntington's disease patients
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AIM: Huntington's disease (HD) is an inherited disease caused by an expansion of cytosine-adenine-guanine (CAG) repeats in the huntingtin gene (HTT) that ultimately leads to neurodegeneration. To study the molecular basis of this disease, induced pluripotent s... ...