Breviscapine suppresses the growth of non-small cell lung cancer by enhancing microRNA-7 expression [0.03%]
益气迷仙术通过增强microRNA-7表达抑制非小细胞肺癌生长
Jian Zeng,Shunv Cai
Jian Zeng
Breviscapine (BVP) has previously been shown to inhibit the proliferation of hepatocellular carcinoma cells. However, little is known about the effects of BVP on non-small cell lung cancer (NSCLC) growth. Here, we aimed to study the effects...
Molecular analysis of the human faecal archaea in a southern Indian population [0.03%]
南部印度人群中人体粪便古菌的分子分析
Sandya B Rani,Ramadass Balamurugan,Balakrishnan S Ramakrishna
Sandya B Rani
Archaea are an important constituent of the human gut microbiota, but there is no information on human gut archaea in an Indian population. In this study, faecal samples were obtained from different age groups (neonatal babies, preschool ch...
MicroRNA-144 inhibits hepatocellular carcinoma cell proliferation, invasion and migration by targeting ZFX [0.03%]
微小核糖核酸-144通过靶向锌指蛋白同源盒基因抑制肝癌细胞增殖、侵袭和迁移
Hongbin Bao,Xinguo Li,Hengli Li et al.
Hongbin Bao et al.
MicroRNA 144 (miR-144), a small non-coding RNA, is frequently dysregulated in human several tumour progression, but its role and the underlying mechanisms in hepatocellular carcinoma (HCC) is poorly investigated. In the present study, the e...
Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status [0.03%]
不同TP53状态的膀胱癌细胞中白蜡素的细胞毒性和毒性基因组效应
Daiane Teixeira DE Oliveira,Andre Luiz Ventura Savio,Joao Paulo DE Castro Marcondes et al.
Daiane Teixeira DE Oliveira et al.
Silibinin is a natural phenol found in the seeds of the milk thistle plant. Recent data have shown its effectiveness for preventing/treating bladder tumours. Therefore, in this study we investigated the cytotoxic and toxicogenetic activity ...
Genetic architecture of seed longevity in bread wheat (Triticum aestivum L.) [0.03%]
面包小麦(Triticum aestivum L。)种子长寿的遗传结构
Mian Abdur Rehman Arif,Manuela Nagel,Ulrike Lohwasser et al.
Mian Abdur Rehman Arif et al.
The deterioration in the quality of ex situ conserved seed over time reflects a combination of both physical and chemical changes. Intraspecific variation for longevity is, at least in part, under genetic control. Here, the grain of 183 bre...
Extra-oviductal expression of oviductal glycoprotein 1 in mouse: Detection in testis, epididymis and ovary [0.03%]
小鼠输卵管糖蛋白1的非输卵表达：在睾丸、附睾和卵巢中的检测
Saniya Laheri,Deepak Modi,Purvi Bhatt
Saniya Laheri
Oviductal glycoprotein 1 (OVGP1), also called oviductin, is an oviduct-specific protein and is suggested to play a role in fertilization. Traditionally, Ovgp1 has been shown to be exclusively expressed by the oviduct; however, recent studie...
AtMBD6, a methyl CpG binding domain protein, maintains gene silencing in Arabidopsis by interacting with RNA binding proteins [0.03%]
甲基化CpG结合域蛋白ATMBD6通过与RNA结合蛋白相互作用在拟南芥中维持基因沉默
Adwaita Prasad Parida,Amrapali Sharma,Arun Kumar Sharma
Adwaita Prasad Parida
DNA methylation, mediated by double-stranded RNA, is a conserved epigenetic phenomenon that protects a genome from transposons, silences unwanted genes and has a paramount function in plant or animal development. Methyl CpG binding domain p...
Wulong Liang,Minping Zheng,Changlei Bao et al.
Wulong Liang et al.
The Golgi apparatus and its resident proteins are utilized and regulated by viruses to facilitate their proliferation. In this study, we investigated Classical swine fever virus (CSFV) proliferation when the function of the Golgi was distur...
Constitutively activated ERK sensitizes cancer cells to doxorubicin: Involvement of p53-EGFR-ERK pathway [0.03%]
ERK的组成型活化增强癌细胞对阿霉素的敏感性：p53-EGFR-ERK途径参与其中
Ratna Kumari,Surbhi Chouhan,Snahlata Singh et al.
Ratna Kumari et al.
The tumour suppressor gene p53 is mutated in approximately 50% of the human cancers. p53 is involved in genotoxic stress-induced cellular responses. The role of EGFR and ERK in DNA-damage-induced apoptosis is well known. We investigated the...
Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction [0.03%]
hsa-miR-939过表达通过NGFR下调和减少细胞凋亡实现肿瘤促进作用
Fahimeh Hosseini Aghdaei,Bahram M Soltani,Sadat Dokanehiifard et al.
Fahimeh Hosseini Aghdaei et al.
Neurotrophin receptors play a crucial role in neuronal survival, differentiation and regeneration. Nerve growth factor receptor (NGFR) or P75NTR is a neurotrophin receptor that is involved in many pathological conditions including cancers. ...