Jagmohan Singh
Jagmohan Singh
Raju Kumar,Murali D Bashyam
Raju Kumar
β-Catenin is essential for embryonic development and required for cell renewal/regeneration in adult life. Cellular β-catenin exists in three different pools: membranous, cytoplasmic and nuclear. In this review, we focus on functions of t...
Indrani Bose,Mainak Pal
Indrani Bose
Cell differentiation is an important process in living organisms. Differentiation is mostly based on binary decisions with the progenitor cells choosing between two specific lineages. The differentiation dynamics have both deterministic and...
MiR-876-5p suppresses epithelial-mesenchymal transition of lung cancer by directly down-regulating bone morphogenetic protein 4 [0.03%]
微RNA-876-5p通过直接下调骨形态发生蛋白4抑制肺癌上皮间质转化
Liang Bao,Lei Lv,Jinping Feng et al.
Liang Bao et al.
Lung cancer is the leading cause of cancer-related death throughout the world. We aimed to investigate the role of a novel microRNA-876-5p and its potential molecular target bone morphogenetic protein 4 (BMP-4), in the epithelial-mesenchyma...
Enthalpy-entropy compensation and the isokinetic temperature in enzyme catalysis [0.03%]
焓熵补偿及酶催化的等速率温度效应
Athel Cornish-Bowden
Athel Cornish-Bowden
Enthalpy-entropy compensation supposes that differences in activation enthalpy ΔH++ for different reactions (or, typically in biochemistry, the same reaction catalysed by enzymes obtained from different species) may be compensated for by d...
In vitro leishmanicidal, antibacterial and antitumour potential of anhydrocochlioquinone A obtained from the fungus Cochliobolus sp [0.03%]
从轮枝孢菌中获得的无水壳休奎农酮A的体外抗利什曼病、抗菌和抗肿瘤潜能
Fernanda F Campos,Jonas P Ramos,Djalma M DE Oliveira et al.
Fernanda F Campos et al.
The bioassay-guided fractionation of the ethyl acetate extract of the fungus Cochliobolus sp. highlighted leishmanicidal activity and allowed for anhydrocochlioquinone A (ANDC-A) isolation. MS, 1D and 2D NMR spectra of this compound were in...
IGF1 stimulates differentiation of primary follicles and their growth in ovarian explants of zebrafish (Danio rerio) cultured in vitro [0.03%]
胰岛素样生长因子1通过体外培养促进斑马鱼始基卵泡的分化及生长发育
Pancharatna A Katti,Sheetal S Narvekar,Basavaraj B Goundadkar et al.
Pancharatna A Katti et al.
The present study is an attempt to elucidate the involvement of insulin-like growth factor (IGF1) in the differentiation and growth of primary follicles in ovarian explant cultures of zebrafish. Ovaries from adult females were cultured in t...
MicroRNA-146 protects A549 and H1975 cells from LPS-induced apoptosis and inflammation injury [0.03%]
microRNA-146通过抑制NF-κB信号通路保护A549和H1975细胞免受LPS诱导的炎症损伤及细胞凋亡
Qiang Wang,Dagang Li,Yuquan Han et al.
Qiang Wang et al.
Pneumonia is an inflammatory condition affecting the lungs, in which pro-inflammatory cytokines are secreted. It has been shown that microRNA-146 (miR-146) is involved in the regulation of immune and inflammatory responses. The present stud...
Klebsiella pneumoniae antibiotic resistance identified by atomic force microscopy [0.03%]
原子力显微镜识别肺炎克雷伯氏菌的抗生素抗性
Vincenzo Ierardi,Paolo Domenichini,Silvia Reali et al.
Vincenzo Ierardi et al.
In the last decade the detection of the resistance of bacteria to antibiotics treatment, developed by different kind of bacteria, is becoming a huge problem. We hereby present a different approach to the current problem of detection of bact...
Small phosphatidate phosphatase (TtPAH2) of Tetrahymena complements respiratory function and not membrane biogenesis function of yeast PAH1 [0.03%]
短链磷脂酸磷酸酶(TtPAH2)可互补酵母PAH1的呼吸功能而不能互补其膜生物发生功能
Anoop Narayana Pillai,Sushmita Shukla,Sudhanshu Gautam et al.
Anoop Narayana Pillai et al.
Phosphatidate phosphatases (PAH) play a central role in lipid metabolism and intracellular signaling. Herein, we report the presence of a low-molecular-weight PAH homolog in the single-celled ciliate Tetrahymena thermophila. In vitro phosph...