High temperatures influence sexual development differentially in male and female tadpoles of the Indian skipper frog, Euphlyctis cyanophlyctis [0.03%]
高温通过不同方式影响印度隐士蛙(Euphlyctis cyanophlyctis)雄蛙和雌蛙的性发育
Samadhan Krushna Phuge
Samadhan Krushna Phuge
Although sex determination in amphibians is believed to be a genetic process, environmental factors such as temperature are known to influence the sex differentiation and development. Extremely low and high temperatures influence gonadal de...
Cinnamomum osmophloeum Kanehira ethanol extracts prevents human liver-derived HepG2 cell death from oxidation stress by induction of ghrelin gene expression [0.03%]
姜柳提取物通过诱导ghrelin基因表达预防氧化压力引起的肝癌细胞凋亡
Shu-Ying Liu,Chih-Hao Huang,Jia-Ching Shieh et al.
Shu-Ying Liu et al.
Diabetes patients associated with liver disease carry a significant risk of morbidity and mortality. Cinnamon has been reported to reduce fructose-induced oxidative stress in the rat liver. However, the mechanism by which cinnamon protects ...
Cholesterol-lowering drug, in combination with chromium chloride, induces early apoptotic signals in intracellular L. donovani amastigotes, leading to death [0.03%]
他汀类药物联合氯化铬诱导溶组织内阿米巴包囊早期凋亡信号导致致死效应
Amit Kumar Verma,Bhakti Laha,Monika Pandey et al.
Amit Kumar Verma et al.
Leishmania establishes a successful parasitism by evading both oxidative and non-oxidative killing pathways, and its drug resistance against the currently available therapeutics demands for a safe and cheap drug. Since the parasite synthesi...
Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer [0.03%]
靶向敲低切割多聚腺苷酸化特异因子1抑制人卵巢癌细胞增殖
Beiguang Zhang,Ying Liu,Donghui Liu et al.
Beiguang Zhang et al.
Cleavage and polyadenylation specificity factor 1 (CPSF1), a member of CPSF complex, has been reported to play a key role in pre-mRNA 3'-end formation, but its possible role in ovarian cancer remains unclear. In the present study, we found ...
Knockdown of Cripto-1 inhibits the proliferation, migration, invasion, and angiogenesis in prostate carcinoma cells [0.03%]
下调原癌基因Cripto-1可抑制前列腺癌细胞的增殖、迁移、侵袭和血管生成作用
Ding Wu,Zhan Shi,Hao Xu et al.
Ding Wu et al.
Cripto-1 (CR-1) is a member of the epidermal growth factor-Cripto-1/FRL1/Cryptic gene family that plays a key role in the various malignant cancers. However, the role of CR-1 in prostate carcinoma (PCa) remains limited. The expression of CR...
miR-200a-3p promotes b-Amyloid-induced neuronal apoptosis through down-regulation of SIRT1 in Alzheimer's disease [0.03%]
miR-200a-3p通过下调SIRT1促进β淀粉样蛋白诱导的阿尔茨海默病神经元凋亡
Qi-Shun Zhang,Wei Liu,Guang-Xiu Lu
Qi-Shun Zhang
The aberrantly expressed microRNAs (miRNAs) including miR-200a-3p have been reported in the brains of Alzheimer's disease (AD) patients in recent researches. Nevertheless, the role of miR-200a-3p in AD has not been characterized. The purpos...
Protein complex finding and ranking: An application to Alzheimer's disease [0.03%]
蛋白质复合物寻找与排序及其在阿尔茨海默病中的应用
Pooja Sharma,Dhruba K Bhattacharyya,Jugal K Kalita
Pooja Sharma
Protein complexes are known to play a major role in controlling cellular activity in a living being. Identifying complexes from raw protein-protein interactions (PPIs) is an important area of research. Earlier work has been limited mostly t...
Differential reduction of reactive oxygen species by human tissuespecific mesenchymal stem cells from different donors under oxidative stress [0.03%]
人组织特异性间充质干细胞在氧化应激下产生反应性氧族自由基的差异减少作用不同供者之间的比较研究
Swati Paliwal,Anupama Kakkar,Rinkey Sharma et al.
Swati Paliwal et al.
Clinical trials using human Mesenchymal Stem Cells (MSCs) have shown promising results in the treatment of various diseases. Different tissue sources, such as bone marrow, adipose tissue, dental pulp and umbilical cord, are being routinely ...
Amalaki Rasayana improved memory and neuronal metabolic activity in AbPP-PS1 mouse model of Alzheimer's disease [0.03%]
阿姆拉查汗对APP/PS1阿尔茨海默病小鼠模型的改善记忆和神经元代谢活性的影响
Vivek Tiwari,Kamal Saba,Pandichelvam Veeraiah et al.
Vivek Tiwari et al.
Alzheimer's disease (AD) is the most common neurodegenerative disorder characterized by progressive loss of memory and cognitive function. The cerebral metabolic rate of glucose oxidation has been shown to be reduced in AD. The present stud...
What history tells us XLIII Bacteriophage: The contexts in which it was discovered [0.03%]
噬菌体的发现历程与发展环境
Michel Morange
Michel Morange