The many roads to C. elegans dauer arrest: A review and perspective [0.03%]
关于秀丽隐杆线虫幼虫二龄站停留(dauer)的多条途径——综述与观点
Kavinila Selvarasu,Abhishiktha Godthi,Veena Prahlad
Kavinila Selvarasu
The Caenorhabditis elegans dauer stage is an alternative developmental stage to the third larval stage of the nematode. The decision to enter the dauer stage instead of continuing development into reproductive adults is triggered during the...
Review
Journal of biosciences. 2025:50:41. DOI: 2025
ARP2/3 regulates cell surface dynamics of CeTOCA-1 in C. elegans zygotes [0.03%]
C.elegans受精卵中CeTOCA-1细胞表面动态由ARP2/3调节
Aadya Nageswaran,Promiti Mitra,Megha Rai et al.
Aadya Nageswaran et al.
Polymerization of branched actin networks by the ARP2/3 complex plays a critical role in diverse cellular processes. ARP2/3 activity is tightly controlled by the upstream CDC-42 GTPase and effectors such as the Wiscott-Aldrich syndrome prot...
Pharmaceutical adoption of microphysiological systems in India is contingent on their economics among other aspects [0.03%]
印度药企采用微生理系统取决于其经济性等多重因素
Kasturi Mahadik,Surat Parvatam,Nalam Madhusudhana Rao
Kasturi Mahadik
Microphysiological systems (MPS) have enabled a paradigm shift from reliance on animals to human-relevant tools for drug development. Following progressive regulations by USA, Europe, Canada, and other nations, India authorized the use of M...
Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder [0.03%]
慢性注射吗啡可诱发海洛因成瘾者产生抗吗啡抗体并导致免疫抑制
Sidhanta Nanda,Mohammad Adeel Zafar,Sanpreet Singh et al.
Sidhanta Nanda et al.
Globally, opioid use disorder (OUD) presents a significant public health challenge linked to high mortality and disability rates. Heroin and other morphine derivatives are prevalent among abused opioids. Prolonged exposure to these substanc...
Changes in c-Fos protein expression in telencephalic hemispheres of a neotropical fish Piaractus orinoquensis after exposure to a glyphosate-based herbicide [0.03%]
一种热带鱼类Piaractus orinoquensis暴露于草甘膦除草剂后的大脑半球c-Fos蛋白表达变化
Iveth Caroline Ocampo Rincón,Sergio Conde Ocazionez,Hernán Hurtado Giraldo et al.
Iveth Caroline Ocampo Rincón et al.
Glyphosate-based herbicides (GBHs) can be found in waterbodies and may affect aquatic populations, resulting in physiological and behavioral impairments. In Colombia, white cachama (Piaractus orinoquensis) are frequently found in areas subj...
Ex vivo expansion of human disc chondrocytes from surgically removed disc tissue: Post-operative tissue stability [0.03%]
人椎间盘软骨细胞的体外扩增：术后组织稳定性研究
Ankita Bendre,Rohini Lad,Sharwani Dole et al.
Ankita Bendre et al.
Cell therapy using autologous, ex vivo expanded chondrocytes from surgically removed disc tissues has emerged as a promising treatment option for patients with degenerated intervertebral discs. One critical aspect of this is the requirement...
Whole exome sequencing reveals novel and rare variants in nonsyndromic hearing loss-related genes: A focus on GPSM2 compound heterozygosity [0.03%]
全外显子组测序在非综合征性听力损失相关基因中发现新的罕见变异突变体：GPSM2复合杂合突变体的聚焦研究
Sudipta Chakraborty,Sukanya Mitra,Arnab Ghosh et al.
Sudipta Chakraborty et al.
Non-syndromic hearing loss (NSHL) is a genetically heterogeneous disorder affecting millions worldwide. Recent advances in genetic technologies have expanded our understanding of its molecular basis, but challenges remain in identifying and...
Isolation of a novel marine Aspergillus fumigatus strain AFK11 and inhibition of inflammatory mediators [0.03%]
一株新型海洋烟曲霉菌AFK11的分离及其对炎症介质的抑制作用
Kranti Kiran Reddy Ealla,Neema Kumari,Se-Kwon Kim et al.
Kranti Kiran Reddy Ealla et al.
Marine fungi are the leading producers of bioactive metabolites with medicinal properties against several diseases. However, since marine species survive in diverse climates, they are usually difficult to culture in laboratory setups, makin...
Germline loss diminishes somatic mitochondria but confers preservation of respiratory function during aging and hypothermia [0.03%]
生殖系损耗降低了体细胞线粒体的数量，但可以在衰老和低温时保持呼吸功能的稳定
Hye Jin Hwang,Francis R G Amrit,Brandon J Berry et al.
Hye Jin Hwang et al.
Reproductive status influences metabolism and health across the lifespan in diverse ways, and mitochondrial function plays a critical role in mediating this relationship. Using the Caenorhabditis elegans germline ablation model, we investig...
Assay medium composition affects Caenorhabditis elegans thermotaxis behaviours [0.03%]
培养基成分影响秀丽隐杆线虫的热趋性行为
Yanshu Zhang,Masami Shima,Yuki Aoki et al.
Yanshu Zhang et al.
Animals exhibit behavioural responses to environmental stimuli. To date, various experimental assays have been conducted to investigate the molecular and neural mechanisms underlying behavioural responses in Caenorhabditis elegans. However,...