Independent control of functional rewiring after axon injury by let-7 miRNA and insulin/insulin-like growth factor signaling pathways [0.03%]
胰岛素和let-7通路独立调控神经损伤修复过程中的突触重建
Sruthy Ravivarma,Sibaram Behera,Dipanjan Roy et al.
Sruthy Ravivarma et al.
The capability of neurons to regenerate after injury becomes poor in adulthood. Previous studies indicated that loss of either let-7 miRNA or components of insulin/insulin-like growth factor signaling (IIS) can overcome age-related decline ...
Exploring mitochondrial dynamics and localization under cellular stress: A comprehensive insight [0.03%]
探讨细胞应激下的线粒体动力学和定位：全面透视
Saloni Agarwal,Kavikumar Angamuthu Karuppusamy,Abhishek K Gupta
Saloni Agarwal
Within a cell, the mitochondrion serves various functions, including ATP synthesis, generation of reactive oxygen species, maintenance of iron and calcium ion homeostasis, and apoptosis, all of which are essential for the cell's function. R...
Review
Journal of biosciences. 2025:50:23. DOI: 2025
Fatty acid composition, oil yield, and oil content of sunflower (Helianthus annuus L.) across different pollination treatments [0.03%]
不同授粉处理对向日葵（Helianthus annuus L.）脂肪酸组成、出油率和含油量的影响
Kasim Roba Jilo,Mohammed Abu Edeo,Tedale Alemu Hunde et al.
Kasim Roba Jilo et al.
Sunflower oil, widely used in daily human nutrition and in various industrial applications, is economically important. Sunflower seeds are a rich source of healthy unsaturated fats. Fatty acid composition, particularly the ratio of unsatura...
Discovery of potent inhibitors from traditional rice varieties targeting α-amylase: A computational approach and in vitro validation [0.03%]
基于计算方法和体外验证的传统水稻品种中α-淀粉酶作用位点的高效抑制剂的发现
Priya Dharshini Veeraragavan,M Karunanithi,Sathya Albert
Priya Dharshini Veeraragavan
Diabetes involves complex metabolic dysregulation and necessitates approaches such as α-amylase inhibition to moderate postprandial glucose spikes and hyperglycemia. Thus, this study scrutinizes the α-amylase inhibitory potential of selec...
Kinome-wide RNAi screening in Caenorhabditis elegans reveals new modulators of insulin signaling and longevity [0.03%]
基于秀丽隐杆线虫的激酶组RNAi筛选发现胰岛素信号传导和寿命的新调节因子
Manish Chamoli,Anna Foulger,Prachi Singh et al.
Manish Chamoli et al.
The insulin/IGF-I-like signaling (IIS) pathway is a highly conserved signaling cascade that plays a crucial role in regulating longevity across species. Given its significance in aging, identifying novel kinases interacting with the IIS pat...
Meta-analysis of QTLs for drought, heat, and salinity tolerance identifies high-confidence MQTLs and candidate genes in chickpea (Cicer arietinum L.) [0.03%]
基于干旱、高温和盐胁迫的抗性QTL荟萃分析鉴定了高可信度的多环境QTL和候选基因
Shubham Sharma,Jatin Sharma,Shayla Bindra et al.
Shubham Sharma et al.
A meta-analysis of 712 quantitative trait loci (QTLs) associated with traits conferring tolerance to drought, heat, and salinity stress was conducted in chickpea. Of these, 588 QTLs were successfully projected onto a high-density consensus ...
Meta-Analysis
Journal of biosciences. 2025:50:19. DOI: 2025
O-GlcNAc transferase promotes synaptic assembly independent of catalytic activity in C. elegans [0.03%]
O-乙酰葡糖胺转移酶在C. elegans中通过非催化活性促进突触组装
Mengting Wu,Huihui Jiang,Qian Li et al.
Mengting Wu et al.
Synapses are specialized intercellular connections where neurons transfer information, and they are funda mental for complex brain functions. Synaptic assembly is precisely regulated, and its dysfunction often leads to neurodevelopmental di...
Role of public DNA-Seq data in mitogenomics research: A case study on the flying fish family (Beloniformes: Exocoetidae) [0.03%]
公共DNA-Seq数据在线粒体基因组学研究中的作用：以飞鱼科（Beloniformes: Exocoetidae）为例
Iuri Batista DA Silva,Igor Henrique Rodrigues-Oliveira,Karine Frehner Kavalco et al.
Iuri Batista DA Silva et al.
Flying fishes (Exocoetidae) are a highly specialized group of Beloniformes, with 4 subfamilies, 7 genera, and 78 species. However,only a small number of species of flying fishes have the mitochondrial genome described sof ar. Considering th...
C. elegans wired and wireless connectome: insights into principles of nervous system structure and function [0.03%]
C.elegans的有线和无线联结组：对神经系统结构与功能原理的洞见
Keertana Venkatesh,Lidia Ripoll -Sánchez,Isabel Beets et al.
Keertana Venkatesh et al.
Caenorhabditis elegans is one of the primary model organisms for neuroscience research due to its well annotated and compact nervous system. Being the first organism with a mapped connectome, published nearly 40 years ago, it holds a critic...
Review
Journal of biosciences. 2025:50:16. DOI: 2025
Innate immune and endoplasmic reticulum unfolded protein response pathways protect Caenorhabditis elegans against chloroquine toxicity [0.03%]
先天免疫和内质网未折叠蛋白反应途径保护秀丽隐杆线虫免受氯喹毒性的伤害
Rajneesh Rao,Jogender Singh
Rajneesh Rao
Chloroquine (CQ) is a 4-aminoquinoline that has historically been used as an anti-malarial drug. It has also been used to treat several autoimmune diseases, cancers, and viral infections. Most of the effects of CQ are mediated through its a...