Tetrahymena dynamin-related protein 6 self-assembles independent of membrane association [0.03%]
无膜相互作用的tetrahymena dynamin相关蛋白6自我装配
Usha P Kar,Himani Dey,Abdur Rahaman
Usha P Kar
Self-assembly on target membranes is one of the important properties of all dynamin family proteins. Drp6, a dynaminrelated protein in Tetrahymena, controls nuclear remodelling and undergoes cycles of assembly/disassembly on the nuclear env...
Blocking dephosphorylation at Serine 120 residue in t-SNARE SNAP-23 leads to massive inhibition in exocytosis from mast cells [0.03%]
阻断t-SNARE衔接蛋白-23天冬氨酸/赖氨酸激活蛋白酶1磷酸化位点丝氨酸120导致肥大细胞出胞反应大量受抑
Pieu Naskar,Nilofer Naqvi,Niti Puri
Pieu Naskar
Mast cells (MCs) respond to allergen challenge by release of pre-stored inflammatory mediators from their secretory granules, on cross-linking of Fc(epsilon) receptor I (Fc(epsilon)RI) receptors. The target-SNARE (t-SNARE) SNAP-23 has been ...
Glucohexaose-induced protein phosphatase 2C regulates cell redox status of cucumber seedling [0.03%]
葡萄糖六酸诱导的蛋白磷酸酶2C调控黄瓜幼苗细胞氧化还原状态
Q M Chen,Y Yu,C M Lin et al.
Q M Chen et al.
Protein Phosphatase 2C (PP2C) is an important phosphatase-like protein in eukaryotic organisms that can negatively regulate protein kinase cascade abscisic acid (ABA) signal system through phosphorylation and carry out vital roles in variou...
Root transcripts associated with arsenic accumulation in hyperaccumulator Pteris vittata [0.03%]
蜈蚣草砷超积累的根部转录组分析
Rasika M Potdukhe,Priyanka Bedi,Bijaya K Sarangi et al.
Rasika M Potdukhe et al.
Hyperaccumulation of arsenic (As) by brake fern Pteris vittata has been described as an important genetic trait that provides an option for development of a sustainable phytoremediation process for As mitigation. Accumulation of very high c...
Target-specific delivery of doxorubicin to human glioblastoma cell line via ssDNA aptamer [0.03%]
通过单链DNA适配体向人脑胶质母细胞瘤细胞系特异性递送阿霉素
Abdullah Tahir Bayrac,Oya Ercan Akca,Fusun Inci Eyidogan et al.
Abdullah Tahir Bayrac et al.
Targeted drug delivery approaches have been implementing significant therapeutic gain for cancer treatment since last decades. Aptamers are one of the mostly used and highly selective targeting agents for cancer cells. Herein, we address a ...
Acute pharmacogenetic activation of medial prefrontal cortex excitatory neurons regulates anxiety-like behaviour [0.03%]
急性药理遗传学活化内侧前额叶皮层兴奋性神经元可调节类似焦虑的行为
Sthitapranjya Pati,Ankit Sood,Sourish Mukhopadhyay et al.
Sthitapranjya Pati et al.
The medial prefrontal cortex (mPFC) is implicated in anxiety-like behaviour. In rodent models, perturbations of mPFC neuronal activity through pharmacological manipulations, optogenetic activation of mPFC neurons or cell-type specific pharm...
PAX6 can substitute for LHX2 and override NFIA-induced astrogliogenesis in developing hippocampus in vivo [0.03%]
PAX6可以替代LHX2并抑制NFIA诱导的海马体在体星形胶质细胞分化
Veena Kinare,Ashwin S Shetty,Agasthya Suresh et al.
Veena Kinare et al.
In the developing central nervous system, transcription factors play a crucial role in the regulation of cell fate. Previously we demonstrated that LHX2 is a critical regulator of the neuron-glia cell fate switch in the developing mouse hip...
Thalassiosira mala (Bacillariophyta), a potentially harmful, marine diatom from Chilka Lake and other coastal localities of Odisha, India: Nomenclature, frustule morphology and global biogeography [0.03%]
印度奥迪沙邦奇尔卡湖和其它沿海地点的一种潜在有害海洋颗虫藻——塔拉西奥西拉马ла（Bacillariophyta）：命名法、壳体形态及全球生物地理分布
Akshinthala K S K K S K Prasad,James A Nienow,Eric Lochner
Akshinthala K S K K S K Prasad
An individual-level selection model for the apparent altruism exhibited by cellular slime moulds [0.03%]
一个解释细胞变形虫表现出来的利他行为的个体选择模型
Amotz Zahavi,Keith D Harris,Vidyanand Nanjundiah
Amotz Zahavi
In Dictyostelium discoideum, cells that become part of the stalk or basal disc display behaviour that can be interpreted as altruistic. Atzmony et al. (Curr Sci 72:142-145, 1997) had hypothesised that this behaviour could be the outcome of ...
ATR kinase regulates its attenuation via PPM1D phosphatase recruitment to chromatin during recovery from DNA replication stress signalling [0.03%]
DNA复制胁迫信号传导期间ATR激酶通过招募PPM1D磷酸酶到染色质调节其衰减作用
Debadrita Bhattacharya,Disha Hiregange,Basuthkar J Rao
Debadrita Bhattacharya
In eukaryotes, in response to replication stress, DNA damage response kinase, ATR is activated, whose signalling abrogation leads to cell lethality due to aberrant fork remodelling and excessive origin firing. Here we report that inhibition...