Classical swine fever virus non-structural protein 4B binds tank-binding kinase 1 [0.03%]
经典猪瘟病毒非结构蛋白4B结合肿瘤坏死因子受体关联激酶1
Huifang Lv,Wang Dong,Zhi Cao et al.
Huifang Lv et al.
Classical swine fever (CSF) is a contagious disease with a high mortality rate and is caused by classical swine fever virus (CSFV). CSFV non-structural protein 4B (NS4B) plays a crucial role in CSFV replication and pathogenicity. However, p...
Is divalent magnesium cation the best cofactor for bacterial β-galactosidase? [0.03%]
二价镁离子是细菌β-半乳糖苷酶的最佳辅助因子吗？
Goutam Banerjee,Atish Ray,Kazi Nurul Hasan
Goutam Banerjee
β-Galactosidase is a metal-activated enzyme, which breaks down the glucosidic bond of lactose and produces glucose and galactose. Among several commercial applications, preparation of lactose-free milk has gained special attention. The pre...
Profile of pterostilbene-induced redox homeostasis modulation in cardiac myoblasts and heart tissue [0.03%]
pterostilbene诱导的心肌细胞和心脏组织红氧平衡调节机制研究
G K Couto,R O Fernandes,D Lacerda et al.
G K Couto et al.
This study was designed to investigate the effect of pterostilbene (PTS) on cardiac oxidative stress in vitro, as this is a simple and promising methodology to study cardiac disease. Cardiac myoblasts (H9c2 cells) and homogenised cardiac ti...
Primary study on the hypoglycemic mechanism of 5rolGLP-HV in STZ-induced type 2 diabetes mellitus mice [0.03%]
5 rol GLP HV对STZ诱导的Ⅱ型糖尿病小鼠的降糖机制初探
Yanan Wang,Minggang Li,Zaizhong Ni
Yanan Wang
5rolGLP-HV is a promising dual-function peptide for the treatment of diabetes and thrombosis simultaneously. For investigating the therapeutic mechanism of 5rolGLP-HV for type 2 diabetes mellitus (T2DM), STZ-induced diabetic mice were estab...
MiR-92a inhibits fibroblast-like synoviocyte proliferation and migration in rheumatoid arthritis by targeting AKT2 [0.03%]
miR-92a通过靶向Akt2抑制滑膜成纤维细胞的增殖和迁移以治疗类风湿性关节炎
Fang-Yuan Yu,Cong-Qin Xie,Chang-Liang Jiang et al.
Fang-Yuan Yu et al.
Growing data have indicated that the miR-17-92 cluster is implicated in inflammatory response and rheumatoid arthritis (RA). This study was aimed to investigate the effects of miR-92a on the proliferation and migration of rheumatoid arthrit...
Neuroectodermal stem cells: A remyelinating potential in acute compressed spinal cord injury in rat model [0.03%]
神经外胚层干细胞：在急性脊髓损伤大鼠模型中具有脱髓鞘再生潜能
Wafaa S Ramadan,Ghada A Abdel-Hamid,Saleh Al-Karim et al.
Wafaa S Ramadan et al.
The outcomes of compressed spinal cord injury (CSCI) necessitate radical treatment. The therapeutic potential of neuroectodermal stem cells (NESCs) in a rat model of CSCI in acute and subacute stages was assessed. White Wistar rat were divi...
Decreased PGC1- α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism [0.03%]
甲状腺功能亢进相关心脏肥厚中PGC1- α水平降低和促凋亡蛋白信号增加有关
Rayane Brinck Teixeira,Tatiane Evelyn Barboza,Carla Cristina DE Araujo et al.
Rayane Brinck Teixeira et al.
Hyperthyroidism can lead to the activation of proteins which are associated with inflammation, apoptosis, hypertrophy, and heart failure. This study aimed to explore the inflammatory and apoptotic proteins involved in the hyperthyroidism-in...
Trait anxiety and neural efficiency of abstract reasoning: An fMRI investigation [0.03%]
特质焦虑与抽象推理的神经效率：一项fMRI研究
Shilpi Modi,Mukesh Kumar,Sanjeev Nara et al.
Shilpi Modi et al.
Worries preoccupy the working memory capacity in anxious individuals, thereby affecting their performance during tasks that require efficient attention regulation. According to the attentional control theory (ACT), trait anxiety affects the...
Synaptojanin regulates Hedgehog signalling by modulating phosphatidylinositol 4-phosphate levels [0.03%]
synaptojanin通过调节磷脂酰肌醇4-磷酸的水平来调控Hh信号通路
Shital Sarah Ahaley
Shital Sarah Ahaley
In Hedgehog (Hh) signalling, Hh ligand concentration gradient is effectively translated into a spatially distinct transcriptional program to give precisely controlled context dependent developmental outcomes. In the absence of Hh, the recep...
Ursolic acid stimulates UCP2 expression and protects H9c2 cells from hypoxia-reoxygenation injury via p38 signaling [0.03%]
乌索酸通过p38信号刺激UCP2的表达并保护H9c2细胞免受缺氧/复氧损伤
Min Chen,Xiaodong Wang,B O Hu et al.
Min Chen et al.
Oxidative stress and apoptosis is involved in hypoxia-reoxygenation (H/R) induced myocardial injury. Increased expression of uncoupling protein 2 (UCP2), a cationic carrier protein, has protective effect against H/R injury. The present stud...