Isolation of a novel marine Aspergillus fumigatus strain AFK11 and inhibition of inflammatory mediators [0.03%]
一株新型海洋烟曲霉菌AFK11的分离及其对炎症介质的抑制作用
Kranti Kiran Reddy Ealla,Neema Kumari,Se-Kwon Kim et al.
Kranti Kiran Reddy Ealla et al.
Marine fungi are the leading producers of bioactive metabolites with medicinal properties against several diseases. However, since marine species survive in diverse climates, they are usually difficult to culture in laboratory setups, makin...
Germline loss diminishes somatic mitochondria but confers preservation of respiratory function during aging and hypothermia [0.03%]
生殖系损耗降低了体细胞线粒体的数量，但可以在衰老和低温时保持呼吸功能的稳定
Hye Jin Hwang,Francis R G Amrit,Brandon J Berry et al.
Hye Jin Hwang et al.
Reproductive status influences metabolism and health across the lifespan in diverse ways, and mitochondrial function plays a critical role in mediating this relationship. Using the Caenorhabditis elegans germline ablation model, we investig...
Assay medium composition affects Caenorhabditis elegans thermotaxis behaviours [0.03%]
培养基成分影响秀丽隐杆线虫的热趋性行为
Yanshu Zhang,Masami Shima,Yuki Aoki et al.
Yanshu Zhang et al.
Animals exhibit behavioural responses to environmental stimuli. To date, various experimental assays have been conducted to investigate the molecular and neural mechanisms underlying behavioural responses in Caenorhabditis elegans. However,...
Pan-cancer analysis of cancer-specific transcript isoforms reveals the regulatory impact of isoform switching on the alteration of the interplay between RBPs and miRNAs in cancers [0.03%]
泛癌分析癌症特异性转录本异构体揭示异构体转换对癌症中RBPs和miRNA之间相互作用改变的调控影响
Sukhen DAS Mandal,Sumit Mukherjee
Sukhen DAS Mandal
The switch in the predominantly expressed transcript isoform of the same gene has been identified as a significant factor in the progression of various types of cancer. These switches can impact the gain or loss of different 3'UTRs, which a...
Evolution of body size and selfhood: Size-scaling from selfless reproduction to enhanced self-preservation [0.03%]
身体大小和自我意识的进化：从无私繁殖到增强自我保护的规模调整规律
Douglas S Glazier
Douglas S Glazier
Our knowledge of how and why various biological and ecological traits relate (scale) to body size has grown at a rapid pace. In this exploratory analysis, I aim to further advance our knowledge of biological scaling by arguing that individu...
Review
Journal of biosciences. 2025:50:30. DOI: 2025
What keeps Caenorhabditis elegans precise: The spatiotemporal regulation of defecation [0.03%]
调控秀丽隐杆线虫精确排泄的时空机制研究
Qiang Liu,Louis Tao
Qiang Liu
Rhythmic behaviors controlled by internal biological clocks are universal among living organisms, ranging from single cells to humans. The inner workings and modulations of the intrinsic oscillatory activities that underlie these rhythmic b...
Review
Journal of biosciences. 2025:50:29. DOI: 2025
A jack of all trades: Hermaphrodite-specific serotonergic neuron in C. elegans [0.03%]
多重身份的调节者：秀丽隐杆线虫的雄性特异性血清素能神经元
Patrick Laurent
Patrick Laurent
How does a single neuron type shape both short- and long-term behavior? A study reveals how co-transmission by two hermaphrodite-specific neurons (HSNs) of Caenorhabditis elegans produces both transient and long-lasting effects on its egg-l...
Identifying trials run in India, registered with ClinicalTrials.gov, is not straightforward [0.03%]
在ClinicalTrials.gov网站上识别在美国境外开展的临床试验——以印度为例
Anwesha Dhal Samanta,Jaishree Mendiratta,Gayatri Saberwal
Anwesha Dhal Samanta
Clinical trial registries are invaluable resources for many stakeholders. However, these registries often require customized methodologies to identify studies of interest. To determine what steps it would take to catalog every trial that ha...
Why does community ecology need chemistry? Because keystone molecules can govern food webs [0.03%]
为什么群落生态学需要化学？因为关键分子可以调控食物网
Renee M Borges
Renee M Borges
In an earlier editorial (Borges 2022), I had talked about the keystone concept formulated by Robert Paine. This important concept (Paine 1966) emphasised the idea that biodiversity is maintained by a top-down process in which the removal of...
Dipankar Nandi,Nikita S Ramteke
Dipankar Nandi
The immune system is our defence network and primarily geared to protect us from pathogens and tumors. This aspect is evident in people who lack or possess a compromised immune system and are, therefore, highly susceptible to infections and...
Review
Journal of biosciences. 2025:50:25. DOI: 2025