G-quadruplex forming region within WT1 promoter is selectively targeted by daunorubicin and mitoxantrone: A possible mechanism for anti-leukemic effect of drugs [0.03%]
鬼臼类拓扑异构酶Ⅱ抑制剂选择性结合WT1启动子区G-四链体：潜在的抗白血病作用机制
Saeedeh Ghazaey Zidanloo,Abasalt Hosseinzadeh Colagar,Hossein Ayatollahi et al.
Saeedeh Ghazaey Zidanloo et al.
Wilms tumor 1 (WT1) has long been overexpressed in acute myeloid leukemia and has a prognostic value in its diagnosis. Lately, the formation of G-quadruplexes in oncogenic promoters like (WT1) has been widely investigated since stabilizatio...
Identification of the miRNA-mRNA regulatory network of antler growth centers [0.03%]
鹿茸生长中心的miRNA-mRNA调控网络识别
Baojin Yao,Mei Zhang,Meixin Liu et al.
Baojin Yao et al.
Antler growth is a unique event compared to other growth and development processes in mammals. Antlers grow extremely fast during the rapid growth stage when growth rate peaks at 2 cm per day. Antler growth is driven by a specific endochond...
Measles virus phosphoprotein inhibits apoptosis and enhances clonogenic and migratory properties in HeLa cells [0.03%]
麻疹病毒磷蛋白可抑制细胞凋亡并增强HeLa细胞的集落形成能力和迁移能力
Sankhajit Bhattacharjee,Rishi Kumar Jaiswal,Pramod Kumar Yadava
Sankhajit Bhattacharjee
Measles virus is the causative agent of measles, a major cause of child mortality in developing countries. Two major proteins, coded by the viral genome, are nucleocapsid protein (N) and phosphoprotein (P). The N protein protects the viral ...
Construction of a dietary-cure Saccharomyces cerevisiae expressing long-acting glucagon-like peptide-1 and investigation of its hypoglycemic activity in type 2 diabetes mellitus mouse model [0.03%]
具有长效胰高血糖素样肽-1分泌功能的食疗酵母酿酒酵母菌株的构建及其降糖作用探讨
Pingzhe Jiang,Chao Ma,Junfeng Hao et al.
Pingzhe Jiang et al.
Bio-drug is a new type of beneficial biology expressing therapeutic peptides (protein) as orally administrated medicine to treat diseases, in particular, chronic diseases like diabetes. In order to develop recombinant yeast strains as a bio...
Influence of some environmental variables and addition of r-lysozyme on efficacy of Vibrio harveyi phage for therapy [0.03%]
环境变量及r-lysostaphin添加对哈维氏弧菌噬菌体治疗效果的影响研究
Tanmoy Gon Choudhury,Biswajit Maiti,M N Venugopal et al.
Tanmoy Gon Choudhury et al.
Bacteriophage therapy is a viable proposition for controlling luminous vibriosis caused by Vibrio harveyi in shrimp aquaculture. However, environmental factors influence the growth and activity of phage and affect its efficiency in controll...
Isolation of a putative virulence agent, cytotoxic serine-elastase, from a newly isolated Pseudomonas aeruginosa ZuhP13 [0.03%]
铜绿假单胞菌ZuhP13毒力因子细胞毒丝氨酸弹性蛋白酶的鉴定与纯化
Essam Kotb,Yehia A El-Zawahry,Ghadeer E Saleh
Essam Kotb
A 48 kDa ZuhP13 elastase from P. aeruginosa isolated from a urine sample was successfully purified to 8.8-fold and 39% recovery by DEAE-Sepharose CL-6B and Sephadex G-100 chromatography. Its ideal reaction values were pH 7.5 and 40°C. It s...
Carbohydrates and polyphenolics of extracts from genetically altered plant acts as catalysts for in vitro synthesis of silver nanoparticle [0.03%]
转基因植物提取物中的碳水化合物和多酚类物质可作为体外合成银纳米粒子的催化剂
Abhishek Kumar,Aaram A Kumar,Aditya P Nayak et al.
Abhishek Kumar et al.
Eco-friendly biosynthetic approach for silver nanoparticles production using plant extracts is an exciting advancement in bio-nanotechnology and has been successfully attempted in nearly 41 plant species. However, an established model plant...
MusatransSSRDB (a transcriptome derived SSR database) - An advanced tool for banana improvement [0.03%]
banana微卫星登陆簿(MusatransSSRDB)(一个基于转录组的SSR登录簿)-香蕉改良的强大工具
Suthanthiram Backiyarani,Arumugam Chandrasekar,Subbaraya Uma et al.
Suthanthiram Backiyarani et al.
Availability of transcriptome datasets for use in accelerated molecular-based breeding in Musa species is limited. Illumina Hiseq technology was employed to determine differential gene expression between the contrasting cultivars for three ...
D-Tryptophan governs biofilm formation rates and bacterial interaction in P. mendocina and S. aureus [0.03%]
D-色氨酸可调控植物乳杆菌和金黄色葡萄球菌生物被膜形成及细菌相互作用
Saheli Ghosh,Asifa Qureshi,Hemantj Purohit
Saheli Ghosh
Biofilm genesis by Pseudomonasand Staphylococcus sp is associated with biofouling in natural settings. D-Tryptophan (D-Trp) inhibits bacterial biofilms and have been proposed for biofouling control applications. In this study, D-Trp signifi...
Bone marrow mesenchymal stem cells protect lungs from smoke inhalation injury by differentiating into alveolar epithelial cells via Notch signaling [0.03%]
骨髓间充质干细胞通过Notch信号分化为肺泡上皮细胞以保护吸入烟雾损伤的肺
Yuan Liang,Cunping Yin,X I Lu et al.
Yuan Liang et al.
To examine the protective effect of transplanting bone marrow mesenchymal stem cells (BMSCs) in treating lung injuryinduced by smoke exposure and to investigate the underlying mechanisms of this protection. SD rats were randomlydivided into...